Norethisterone

Dosage Forms Available

• Norethisterone is available as oral tablets, injectable suspensions, and subdermal implants. It is taken orally or administered through intramuscular injections or implants.

Age and Dose Restrictions

• Norethisterone is typically prescribed for adult women.

Contraindications

• Norethisterone should be used with caution in patients with liver disease, a history of heart attack, stroke, or blood clots, breast cancer or other hormone-sensitive cancers, undiagnosed abnormal vaginal bleeding, porphyria (a blood disorder), diabetes, hypertension, or high cholesterol.
• This medicine is contraindicated in pregnant women as it may harm the foetus. It should also be avoided in women with known allergies to norethisterone or any of its components.

Other Medications to Avoid

• This drug may interact with antiretrovirals (such as ritonavir and efavirenz), antibiotics (like rifabutin and griseofulvin), anticoagulants (such as warfarin), and anti-seizure medications (including topiramate and phenobarbital).
• Before starting any prescription or over-the-counter medications, it's crucial to consult a doctor.

Overdose and Missed Dose

• In case of an overdose, contact your doctor immediately or seek emergency medical care if you experience severe symptoms.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Nausea and vomiting can often be managed by taking the medication with food. If these symptoms are severe, contact your doctor.

Use in Driving and Operating Machinery

• Norethisterone may cause dizziness in some people. Before you know how this medicine affects you, exercise caution while driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Norethisterone is contraindicated in pregnancy as it may cause foetal harm. It should only be used during breastfeeding if the potential benefits outweigh the risks.

Caution in Other Conditions

• Patients with liver disease should use norethisterone with caution and under close medical supervision.

Special Dietary and Lifestyle Recommendations

• Maintain a healthy lifestyle with regular exercise and a balanced diet to help manage menstrual and gynaecological disorders.
• Engage in stress-reducing activities like yoga, meditation, or deep breathing exercises, as stress can sometimes worsen menstrual symptoms.