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Ofloxacin + Satranidazole

Uses of Ofloxacin + Satranidazole

  • Ofloxacin + Satranidazole is primarily used to manage various bacterial infections and belongs to the group of antibiotics.

  • It is also utilised for the management of gastrointestinal infections, gynaecological infections, respiratory tract infections, urinary tract infections, skin and soft tissue infections, and surgical prophylaxis and postoperative infections.

Side effects of Ofloxacin + Satranidazole

  • Nausea

  • Vomiting

  • Abdominal pain

  • Diarrhoea

  • Rash

How Ofloxacin + Satranidazole works

  • Ofloxacin + Satranidazole is a combination of two types of antibiotics.

  • Ofloxacin is a fluoroquinolone antibiotic. It works by blocking the action of enzymes called DNA gyrase and topoisomerase IV in bacteria. These enzymes are necessary for the bacteria to reproduce and repair themselves. Blocking them leads to disruption of DNA replication, transcription, repair, and recombination in the bacteria, causing their death.

  • Satranidazole is a nitroimidazole derivative. It works by getting reduced inside susceptible protozoa and anaerobic bacteria by an enzyme called ferredoxin. Its reduced form damages the DNA, RNA, and proteins in these microorganisms, leading to their death.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ofloxacin + Satranidazole can be taken orally (tablets).

Age and Dose Restrictions

  • This medicine is meant for adults and children who are older than the age where rapid bone growth occurs.

Contraindications

  • This medicine is contraindicated in patients with known allergies to quinolones or nitroimidazoles.

  • It is also contraindicated in growing adolescents, whose bone growth might be affected.

Other Medications to Avoid

  • This combination may interact with several medications, including other antibiotics (such as ciprofloxacin), antacids (like magnesium or aluminum hydroxide), and medications that affect liver enzymes (such as rifampin or phenytoin).

Overdose and Missed Dose

  • An overdose of Ofloxacin + Satranidazole may lead to symptoms such as drowsiness, confusion, dizziness, tremors, or seizures. In such cases, supportive care should be provided including maintaining adequate hydration and monitoring vital signs. Activated charcoal might be considered if ingestion was recent.

  • If a dose is missed, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • To manage nausea or stomach upset, consider taking the medication with food.

  • If experiencing mild diarrhoea, ensure adequate fluid intake to prevent dehydration.

Use in Driving and Operating Machinery

  • This medication might impair your ability to drive or operate machinery. If you experience symptoms like dizziness or seizures, avoid engaging in tasks that require alertness.

Use in Pregnancy and Lactation

  • Ofloxacin + Satranidazole is contraindicated during pregnancy and lactation. The effects on the developing fetus or nursing infant are potentially harmful.

  • Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Exercise caution when using Ofloxacin + Satranidazole if you have renal (kidney) or hepatic (liver) impairment as dose adjustments may be necessary.

  • Patients with known heart conditions such as arrhythmias should use this medicine with caution due to the risk of QT prolongation.

Special Dietary and Lifestyle Recommendations

  • Maintain adequate hydration especially if gastrointestinal symptoms such as diarrhoea occur.

  • Consider eating smaller, more frequent meals if experiencing nausea or abdominal discomfort.

  • Avoid excessive exposure to sunlight or UV light; wear protective clothing and use sunscreen when outdoors to manage photosensitivity reactions.

  • It is important to observe good personal hygiene to help control infection spread especially in gastrointestinal infections.

Frequently asked questions

No, Ofloxacin + Satranidazole is not a steroid. It is a combination of two antibiotics, belonging to the fluoroquinolone and nitroimidazole classes respectively.

There are no known effects of Ofloxacin + Satranidazole on fertility. However, if you have concerns about fertility or are planning a pregnancy, consult with your doctor before starting this medication.

There is no direct evidence to suggest that Ofloxacin + Satranidazole affects sleep. However, some patients may experience insomnia as a side effect. It is important to report any sleep disturbances to your doctor.

No particular diet restrictions are required during the use of Ofloxacin + Satranidazole. However, it is always good to maintain a balanced and healthy diet while under any kind of medication.

Ofloxacin + Satranidazole is safe for daily use if prescribed by your doctor.

Ofloxacin is rapidly absorbed and reaches its peak serum levels within 1-2 hours after oral administration. However, the time it takes for the medicine to show its effect can vary depending on the severity and type of infection.

The best time to take Ofloxacin + Satranidazole will be prescribed by your doctor.

Terms & Conditions


Available medicines for OFLOXACIN + SATRANIDAZOLE
Satrogyl O Dry Syrup 30ml
Satrogyl O Dry Syrup 30ml
Alkem Laboratories Ltd.
Pack of 30 ML
₹58.22
MRP ₹71.00
18.00% OFF
Satromax O 300/200 MG Tablet 10
Satromax O 300/200 MG Tablet 10
Indchemie Health Specialities Pvt. Ltd.
Pack of 10 Units
₹67.05
MRP ₹81.77
18.00% OFF
Satrogyl O Tablet 10
Satrogyl O Tablet 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹147.60
MRP ₹180.00
18.00% OFF
Satrogyl O Dry Syrup 60ml
Satrogyl O Dry Syrup 60ml
Alkem Laboratories Ltd.
Pack of 60 ML
₹102.50
MRP ₹125.00
18.00% OFF

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