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Ofloxacin + Sodium Chloride

Uses of Ofloxacin + Sodium Chloride

  • Ofloxacin + Sodium Chloride is primarily used for managing a variety of bacterial infections and belongs to the class of fluoroquinolone antibiotics and saline infusions.

  • It is indicated for managing infections in different parts of the body, including respiratory tract infections like pneumonia and bronchitis, skin and skin structure infections, urinary tract infections, prostatitis (infection of the prostate gland), and sexually transmitted diseases like gonorrhoea.

Side effects of Ofloxacin + Sodium Chloride

  • Nausea and vomiting

  • Diarrhoea

  • Headache and dizziness

  • Insomnia

  • Injection site reactions such as pain, redness, or burning

How Ofloxacin + Sodium Chloride works

  • Ofloxacin + Sodium Chloride is an antibiotic combination.

  • Ofloxacin, part of the fluoroquinolone class of antibiotics, works by inhibiting vital enzymes in the bacteria known as DNA gyrase and topoisomerase IV. By blocking these enzymes, it hinders the bacteria's ability to replicate and multiply. In simpler terms, it stops the growth and spread of bacteria.

  • Sodium Chloride (commonly known as salt) is used primarily for its properties as an electrolyte and osmotic agent. When administered in combination with ofloxacin, sodium chloride helps to maintain hydration and electrolyte balance in the body during antibiotic treatment.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ofloxacin + Sodium Chloride is available for administration as an intravenous infusion, which means it is administered directly into a vein using a drip.

  • This combination is specifically designed for use in a hospital or clinical setting where the infusion can be monitored by medical professionals.

Age and Dose Restrictions

  • This medicine is meant for use in adults. It has not been established as safe or effective for children.

Contraindications

  • Ofloxacin + Sodium Chloride is contraindicated in patients with known allergies to ofloxacin or other quinolone antibiotics.

  • It is also contraindicated in individuals with epilepsy and other central nervous system disorders.

  • This combination should not be used by individuals with myasthenia gravis, due to the potential worsening of muscle weakness.

  • Patients with a history of tendon disorders induced by quinolones should avoid this medication.

Other Medications to Avoid

  • This combination may interact with antacids containing magnesium or aluminium, iron supplements (such as ferrous sulfate), zinc supplements (like zinc gluconate), anticoagulants (such as warfarin), bronchodilators (including theophylline), anti-inflammatory medications (like ibuprofen and celecoxib), and diabetes medications (such as insulin or metformin).

Overdose and Missed Dose

  • In case of an overdose, the infusion should be stopped immediately, and supportive care should be provided. Ofloxacin + Sodium Chloride is not effectively removed by dialysis; treatment focuses on managing symptoms and supportive care.

  • If a dose is missed, it should be administered as soon as possible unless it is nearly time for the next scheduled dose. Do not double doses to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage nausea, try taking the infusion slowly while lying down.

  • If experiencing dizziness, resting and avoiding sudden movements can help.

  • For mild headaches or dizziness, ensuring adequate hydration by drinking plenty of water might provide relief.

Use in Driving and Operating Machinery

  • Ofloxacin + Sodium Chloride may cause dizziness or visual disturbances. You are advised to avoid driving or operating heavy machinery until you know how this medicine affects you.

Use in Pregnancy and Lactation

  • Ofloxacin + Sodium Chloride should only be used during pregnancy or while breastfeeding if clearly needed and recommended by a doctor. The potential risks should be weighed against the benefits in such cases.

Caution in Other Conditions

  • This medicine should be used with caution by patients with kidney disease or impaired kidney function, as it may require adjustment of dosage.

  • Individuals with G6PD deficiency should also use this medication cautiously due to potential hemolytic reactions.

Special Dietary and Lifestyle Recommendations

  • Patients being treated with Ofloxacin + Sodium Chloride for bacterial infections should ensure adequate hydration to help reduce the risk of crystalluria (presence of crystals in urine) and support overall health.

  • It is recommended to maintain a balanced diet rich in nutrients which can support immune function during treatment.

  • Managing stress through relaxation techniques such as yoga or meditation can help cope with the illness and aid recovery.

  • Adequate rest is crucial; ensure that you get sufficient sleep to aid your body’s healing process.

  • Avoiding excessive caffeine and spicy foods may help mitigate some gastrointestinal side effects like nausea or diarrhoea linked to this medicine.

Frequently asked questions

The length of time that Ofloxacin + Sodium Chloride stays in the body can vary depending on several factors, including dosage, metabolism, and individual health conditions. For specific information, you should consult your doctor.

Ofloxacin + Sodium Chloride infusion contains sodium. If you are on a low-sodium diet, it is important to discuss this with your doctor before starting the medication.

Unusual changes in mood or behaviour are considered serious side effects of Ofloxacin + Sodium Chloride. If you experience such changes while on the medication, seek immediate medical attention.

Natural alternatives may not be as effective or safe as prescribed medications in treating certain bacterial infections. Therefore, it is recommended to take the medication as prescribed by your doctor.

If you have a known allergy to ofloxacin, other quinolone antibiotics, or any of the components of the infusion, using Ofloxacin + Sodium Chloride is contraindicated.

Ofloxacin + Sodium Chloride is an antibiotic medication and does not cause dependency or withdrawal symptoms. However, if you have concerns about these issues, you should consult your doctor.

No data suggests that Ofloxacin + Sodium Chloride affects menstruation. However, if you notice any changes during your period while taking this medication, it is recommended to consult your doctor.

Terms & Conditions


Ofloxacin + Sodium Chloride in other salts

CEFIXIME + OFLOXACINCIPROFLOXACINOFLOXACINOFLOXACIN + METRONIDAZOLEOFLOXACIN + ORNIDAZOLEOFLOXACIN + ORNIDAZOLE + ITRACONAZOLE + CLOBETASOLCEFPODOXIME + OFLOXACINLEVOFLOXACINCLOBETASOL PROPIONATE + OFLOXACIN + ORNIDAZOLE + TERBINAFINECIPROFLOXACIN + CLOTRIMAZOLE + FLUOCINOLONECIPROFLOXACIN + CLOBETASOL PROPIONATE + METRONIDAZOLE + TERBINAFINECLOBETASOL PROPIONATE + ITRACONAZOLE + OFLOXACIN + ORNIDAZOLECLOBETASOL + OFLOXACIN + ORNIDAZOLE + TERBINAFINEDEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINCIPROFLOXACIN + DEXAMETHASONECALCIUM CHLORIDE + POTASSIUM IODIDE + SODIUM CHLORIDEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONESODIUM CHLORIDEOFLOXACIN + PREDNISOLONEBECLOMETHASONE DIPROPIONATE + CLOTRIMAZOLE + LIDOCAINE / LIGNOCAINE + OFLOXACINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINCEFIXIME + LACTOBACILLUS + OFLOXACINOFLOXACIN + RACECADOTRILNITAZOXANIDE + OFLOXACINOFLOXACIN + SATRANIDAZOLEOFLOXACIN + ORNIDAZOLE + RACECADOTRILKETOROLAC + OFLOXACINCALCIUM CHLORIDE + METHYL PARABEN + POTASSIUM IODIDE + PROPYL PARABEN + SODIUM CHLORIDEBETAMETHASONE + OFLOXACINPHENYLMERCURIC NITRATE + SODIUM CHLORIDECALCIUM CHLORIDE + PHENYLMERCURIC NITRATE + POTASSIUM IODIDE + SODIUM CHLORIDEBETAMETHASONE + CIPROFLOXACINDEXTROSE + POTASSIUM CHLORIDE + SODIUM CHLORIDE + SODIUM CITRATECIPROFLOXACIN + ORNIDAZOLEDEXTROSE + SODIUM CHLORIDECIPROFLOXACIN + TINIDAZOLESODIUM BICARBONATE + SODIUM CHLORIDEPOLYETHYLENE GLYCOL + POTASSIUM CHLORIDE + SODIUM BICARBONATE + SODIUM CHLORIDECALCIUM LACTATE + DEXTROSE + MAGNESIUM SULPHATE + POTASSIUM CHLORIDE + SODIUM CHLORIDE + SODIUM CITRATE + TAURINEMETRONIDAZOLE + OFLOXACIN + SIMETHICONEOFLOXACIN + TINIDAZOLECIPROFLOXACIN + METRONIDAZOLELACTOBACILLUS + OFLOXACINAZITHROMYCIN + OFLOXACINAZITHROMYCIN + LEVOFLOXACINCEFPODOXIME PROXETIL + LEVOFLOXACINFLAVOXATE + OFLOXACINBALOFLOXACINAMBROXOL + LEVOFLOXACINLACTOBACILLUS + OFLOXACIN + ORNIDAZOLELACTOBACILLUS + LEVOFLOXACINDEXTROSE + LEVOFLOXACIN
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