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Pentosan Polysulphate Sodium

Uses of Pentosan Polysulphate Sodium

  • Pentosan Polysulphate Sodium is primarily used to manage the symptoms of interstitial cystitis, a chronic condition characterized by bladder pain and discomfort. This medicine belongs to the group of heparinoid drugs.

Side effects of Pentosan Polysulphate Sodium

  • Hair loss

  • Diarrhea

  • Nausea and upset stomach

  • Heartburn

  • Headache

How Pentosan Polysulphate Sodium works

  • Pentosan Polysulphate Sodium is a semi-synthetic medicine known as a heparinoid. It acts by binding itself to the lining of the bladder, forming a protective barrier. This shield works like a coat of armor, protecting the bladder wall from harmful substances present in urine that can cause irritation.

  • Apart from this, Pentosan Polysulphate Sodium also possesses mild anticoagulant properties. In simpler terms, it helps thin the blood and may assist in the prevention of blood clots from forming.

Certified content

Written By

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Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Reviewed By

Dr. Michelle Frank
Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Expert Advice

Dosage Forms Available

  • Pentosan Polysulphate Sodium is available through the oral route (tablets).

Age and Dose Restrictions

  • This medicine is meant for adults only. It is not recommended for use in children or adolescents under the age of 16.

Contraindications

  • Pentosan Polysulphate Sodium is contraindicated in patients with a known allergy to the medicine itself.

  • It should not be used by patients with a history of heparin-induced thrombocytopenia (low platelet count caused by heparin) or any bleeding disorders.

Other Medications to Avoid

  • Pentosan Polysulphate Sodium may interact with anticoagulants (such as warfarin), aspirin, and nonsteroidal anti-inflammatory medicines (like ibuprofen and naproxen).

Overdose and Missed Dose

  • An overdose of Pentosan Polysulphate Sodium may cause symptoms such as bleeding, bruising, or changes in stool color. If you suspect an overdose, consult your doctor immediately.

  • If you forget to take a dose, take it as soon as you remember. But if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Never take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help manage side effects like diarrhea and an upset stomach.

  • Taking the medication with food may help reduce nausea.

Use in Driving and Operating Machinery

  • Pentosan Polysulphate Sodium may cause dizziness in some individuals. If you experience this, avoid driving and operating heavy machinery.

Use in Pregnancy and Lactation

  • It is advisable to consult your doctor before using Pentosan Polysulphate Sodium during pregnancy or lactation.

Caution in Other Conditions

  • Patients with a history of aneurysms or liver disease should exercise caution when using Pentosan Polysulphate Sodium and inform their doctor about these conditions before starting the medication.

Special Dietary and Lifestyle Recommendations

  • Maintain a regular schedule for taking the medicine to ensure consistent effects.

  • Try to include more fiber in your diet to manage symptoms of diarrhea.

  • Limit intake of caffeinated drinks as they may aggravate bladder symptoms.

  • Practice bladder training or pelvic floor muscle exercises to help manage symptoms of interstitial cystitis.

Frequently asked questions

Pentosan Polysulphate Sodium can cause mood changes in some individuals. If you notice any significant changes in your mood or behavior while taking this medicine, you should consult your doctor.

Pentosan Polysulphate Sodium is generally not available over the counter and typically requires a prescription from your doctor.

Sleep disturbances are a possible side effect of Pentosan Polysulphate Sodium.  If you experience any sleep disturbances while taking this medication, consult your doctor.

Generally, Pentosan Polysulphate Sodium is considered safe for long-term use when taken as prescribed by a doctor. However, regular follow-up appointments are necessary to monitor for any potential side effects or complications.

Do not stop taking Pentosan Polysulphate Sodium without consulting your doctor first, even if your symptoms improve. Abruptly stopping the medication may lead to a recurrence of symptoms.

No, Pentosan Polysulphate Sodium is a semi-synthetic medicine known as a heparinoid, which is primarily used to manage interstitial cystitis, a condition associated with bladder pain and discomfort.

There might be other medicines that manage interstitial cystitis, but their effectiveness and safety may vary. Always consult your doctor for the best medicine suited for your condition.

Terms & Conditions

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