Piperazine

Dosage Forms Available

• Piperazine can be taken orally (tablets, capsules, syrup, and suspension). It can also be used as an enema for rectal administration.

Age and Dose Restrictions

• This medicine is suitable for adults and children over 2 years of age.

Contraindications

• Piperazine is contraindicated in individuals with a known hypersensitivity to the medicine or any of its components.

• It is also contraindicated in patients with a history of seizures, epilepsy or brain lesions.

Other Medications to Avoid

• Piperazine may interact with central nervous system depressants (like benzodiazepines and barbiturates) and anticonvulsant medicines (like phenytoin and carbamazepine).

Overdose and Missed Dose

• Overdose of Piperazine could lead to adverse neurological effects including seizures, particularly in patients with a history of epilepsy or brain lesions. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of Piperazine, take it as soon as you remember. But if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

• For gastrointestinal disturbances such as nausea or vomiting, taking Piperazine with meals may help alleviate these symptoms.

• If you experience drowsiness or dizziness after taking this medicine, avoid activities that require mental alertness until these symptoms subside.

Use in Driving and Operating Machinery

• Piperazine may cause drowsiness, dizziness, or other side effects that might impair your reactions or ability to drive. Therefore, avoid driving or operating machinery until you know how this medication affects you.

Use in Pregnancy and Lactation

• Piperazine is pregnancy category C. It is not known if Piperazine is excreted in human breast milk. Therefore, expectant or breastfeeding mothers should consult their doctor before using this medicine.

Caution in Other Conditions

• Caution is advised when using Piperazine in patients with hepatic or renal impairment, as the medicine is metabolised by the liver and excreted by the kidneys.

• Patients with a history of seizures, epilepsy or brain lesions should also use Piperazine with caution due to its potential neurological effects.

Special Dietary and Lifestyle Recommendations

• Maintain a healthy diet to support your immune system and help prevent parasitic infections.

• Regular hand washing can reduce your risk of contracting parasitic infections which Piperazine is used to manage.