R-fsh
Uses of R-fsh
- R-Fsh is used to manage infertility in both men and women. It belongs to the class of medicines known as gonadotropins.
- In women, R-Fsh is used to stimulate the development and release of eggs from the ovaries, particularly in cases involving assisted reproductive technologies like in-vitro fertilisation. For men diagnosed with hypogonadotropic hypogonadism, R-Fsh is used to stimulate sperm production.
Side effects of R-fsh
- Abdominal pain or bloating
- Mood changes
- Headache
- Injection site reactions
- Nausea or vomiting
How R-fsh works
- R-Fsh is a recombinant follicle-stimulating hormone. It acts by binding to the FSH receptors in the ovaries, just like the body's own FSH. This stimulates the growth and maturity of ovarian follicles, which are small pockets in the ovaries that contain eggs.
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Written By
Bachelor of Dental Surgery
Reviewed By
Doctor of Medicine
Expert Advice
Dosage Forms Available
- R-Fsh is available as a powder to be mixed with a diluent for use as a subcutaneous or intramuscular injection.
Age and Dose Restrictions
- R-Fsh is meant for use in adults of reproductive age.
Contraindications
- R-Fsh is contraindicated in patients with known hypersensitivity to FSH preparations or any component. It is also contraindicated in patients with high levels of FSH indicating primary ovarian failure, uncontrolled thyroid or adrenal dysfunction, ovarian or sex hormone-dependent tumours, and intracranial lesions like pituitary tumours.
Other Medications to Avoid
- R-Fsh may interact with other agents that stimulate ovarian follicular development (such as clomiphene citrate).
Overdose and Missed Dose
- Overdosing on R-Fsh can potentially lead to OHSS, characterised by symptoms like abdominal pain, bloating, nausea, vomiting, and rapid weight gain. In such cases, immediate medical attention is required.
- If you miss a dose of R-Fsh, inform your doctor immediately. Failure to administer the medicine as instructed could disrupt the treatment cycle.
Management of Side Effects
- Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
- Applying ice and rotating injection sites can help reduce injection site reactions such as redness, pain, and bruising.
- Regular rest and intake of fluids can help manage mild symptoms like headache and nausea.
Use in Driving and Operating Machinery
- There are no specific restrictions on driving or operating machinery while on R-Fsh therapy unless you experience side effects that may impair your ability to do so safely.
Use in Pregnancy and Lactation
- R-Fsh is not recommended for use in pregnancy. The safety of R-Fsh during lactation is not established. Breastfeeding mothers should consult their doctor before starting R-Fsh therapy.
Caution in Other Conditions
- Caution is advised for patients with a history of ovarian torsion or ectopic pregnancy.
- Special Dietary and Lifestyle Recommendations
- Adequate rest and stress management may help improve overall well-being and potentially improve response to fertility treatment.
Frequently asked questions
Does R-Fsh have any effect on appetite?
No, It’s not typically associated with effects on appetite, R-Fsh mimics the effects of natural follicle-stimulating hormone (FSH), which plays a crucial role in both female and male reproductive functions.
Is there any natural alternative to R-Fsh?
No known natural alternative provides the same effects as this medicine.
Is R-Fsh a steroid?
No, R-Fsh is not a steroid. It’s a type of hormone used in fertility treatments and is a synthetic version of the naturally occurring follicle-stimulating hormone.
How does R-Fsh differ from the natural FSH produced by the body?
R-Fsh, or Recombinant Follicle Stimulating Hormone, is identical in structure and function to the endogenous FSH produced by our body. However, it is synthesised using recombinant DNA technology, ensuring high purity and consistency across batches, unlike earlier FSH preparations derived from urine.
What is the typical duration of R-Fsh treatment?
The length of R-Fsh treatment is based on individual response. The progress of the treatment is closely monitored via transvaginal ultrasound and serum estrogen levels to prevent potential complications.
Will my insurance cover my R-Fsh treatment?
Coverage for infertility treatments such as R-Fsh varies between insurance providers and plans. It would be prudent to check with your insurance provider for the specifics of your policy. Some insurance plans may require prior authorisation or impose lifetime limits on Assisted Reproductive Technology (ART) cycles.
What is the best time to administer R-Fsh?
The ideal time to administer R-Fsh injection will be decided by your doctor based on your individual needs and treatment plan.
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