Ramipril + S-amlodipine

Dosage Forms Available

• Ramipril + S-Amlodipine is available for use in the form of capsules.

• The route of administration is oral, where the capsules should be swallowed whole with water.

Age and Dose Restrictions

• This medicine is meant for use by adults only.

Contraindications

• Ramipril + S-Amlodipine is contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy.

• It is also contraindicated in patients with hereditary or idiopathic angioedema.

Other Medications to Avoid

• This combination may interact with diuretics and other antihypertensives (such as hydrochlorothiazide and losartan), potassium supplements/potassium-sparing diuretics (like spironolactone and triamterene), lithium, NSAIDs (including ibuprofen and naproxen), simvastatin, and antifungals (e.g., ketoconazole and itraconazole).

Overdose and Missed Dose

• An overdose of Ramipril + S-Amlodipine may result in excessive peripheral vasodilation, leading to marked hypotension, shock, bradycardia, electrolyte disturbances, and potential renal failure. Immediate medical attention is recommended in the event of an overdose.

• If you miss a dose of Ramipril + S-Amlodipine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• If experiencing dizziness or lightheadedness, try lying down until these feelings pass.

• Stay well hydrated to help manage any potential nausea or headaches.

Use in Driving and Operating Machinery

• Ramipril + S-Amlodipine may cause dizziness or drowsiness. If you experience these side effects, avoid driving or operating heavy machinery until you feel safe to do so.

Use in Pregnancy and Lactation

• Ramipril + S-Amlodipine is not recommended during pregnancy due to the risk of harm to the fetus. It should be discontinued as soon as pregnancy is detected.

• Consult your doctor before using this medicine during lactation, as both components are secreted into human milk.

Caution in Other Conditions

• Patients with impaired renal function or those undergoing major surgery that involves anesthesia should exercise caution when using Ramipril + S-Amlodipine.

• People with a history of heart failure or ischemic heart disease need careful monitoring while on this medication.

Special Dietary and Lifestyle Recommendations

• Maintain a diet low in sodium to help control blood pressure levels; avoid adding extra salt to meals.

• Include potassium-rich foods like bananas, oranges, and leafy greens in your diet unless otherwise advised by your doctor.

• Regular physical activity can help lower blood pressure naturally; aim for at least 30 minutes of moderate exercise, such as walking most days of the week.

• Manage stress through relaxation techniques such as deep breathing exercises, meditation, or yoga.

• Monitor your blood pressure regularly to keep track of your progress.