Silymarin + Ursodeoxycholic Acid

Dosage forms available

• Silymarin + Ursodeoxycholic Acid is available as tablets and capsules to be taken orally.

Age and dose restrictions

• This medication is intended for use in adults and children over the age of 12 years.

Contraindications

• Silymarin + Ursodeoxycholic Acid is contraindicated in patients with known allergies to silymarin or Ursodeoxycholic acid.

• It should not be used in patients with bile duct obstruction or intestinal disorders that impair absorption.

Other medications to avoid

• This combination may interact with cytochrome P450 enzyme system metabolisers anti-arrhythmic medication (such as amiodarone), anti-ulcer medication (such as cimetidine), bile acid sequestrants (such as cholestyramine and colestipol) and antidiabetic agents (such as insulin and metformin).

Overdose and missed dose

• Overdose of this combination can lead to symptoms such as severe stomach pain, nausea, vomiting, and jaundice. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it's nearing the time of your next dose, skip the missed one and continue with your regular dosing schedule. Do not double up on the doses.

Management of side effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water may help manage any gastrointestinal symptoms, such as nausea or diarrhoea.

• Taking the medication with food can help minimise stomach discomfort.

Use in driving and operating machinery

• This medication does not usually affect your ability to drive or operate heavy machinery. However, if you experience side effects such as dizziness or fatigue, avoid these activities.

Use in pregnancy and lactation

• It is advisable to consult your doctor before using Silymarin + Ursodeoxycholic Acid during pregnancy or breastfeeding.

Caution in other conditions

• Patients with gallbladder disease or those with severe liver disease should take caution while using this medicine.

Special dietary and lifestyle recommendations

• Maintain a balanced diet, low in saturated fats and high in fruits, vegetables and whole grains, to support overall liver health.

• Moderate exercise can help maintain a healthy weight and improve liver function.

• Avoid the use of illegal substances and unnecessary medications as they can potentially damage the liver.