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Solifenacin + Tamsulosin

Uses of Solifenacin + Tamsulosin

  • Solifenacin + Tamsulosin is primarily used to manage symptoms of benign prostatic hyperplasia (BPH), a condition characterised by the enlargement of the prostate gland. This combination belongs to antimuscarinics and alpha-blockers respectively.

Side effects of Solifenacin + Tamsulosin

  • Dry mouth

  • Constipation

  • Dizziness

  • Headaches

  • Blurred vision

How Solifenacin + Tamsulosin works

  • Solifenacin belongs to the antimuscarinic class of medicines that primarily function to relax the muscles in the bladder. It achieves this by blocking muscarinic receptors that regulate muscle contractions, thereby reducing involuntary contractions and increasing the bladder's capacity to hold urine.

  • Tamsulosin is an alpha-blocker, works by blocking alpha receptors in the prostate and bladder neck muscles. This action relaxes these muscles, improving urine flow and reducing the frequent urge to urinate.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Solifenacin + Tamsulosin is available in tablet or capsule form for oral administration.

Age and Dose Restrictions

  • Solifenacin + Tamsulosin is intended for use in adults only. It is not for use in children or adolescents.

Contraindications

  • Solifenacin + Tamsulosin is contraindicated in individuals with known hypersensitivity to any of its ingredients.

  • It is also contraindicated in patients with urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, severe liver or kidney impairment, myasthenia gravis, severe constipation, and any obstruction in the digestive system.

Other Medications to Avoid

  • This medicine may interact with anticholinergics (e.g., atropine), alpha-blockers (e.g., prazosin), CYP3A4 inhibitors (e.g., ketoconazole), CYP3A4 inducers (e.g., rifampin), and antihistamines (e.g., diphenhydramine). Always consult your healthcare provider for guidance on medication interactions.

Overdose and Missed Dose

  • An overdose of Solifenacin + Tamsulosin may result in severe dizziness, fainting, severe constipation, difficulty urinating, and irregular heartbeat. Immediate medical attention or contact with a poison control center is crucial in case of overdose symptoms.

  • If you miss a dose of Solifenacin + Tamsulosin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Dry mouth can be managed by drinking plenty of fluids and chewing sugar-free gum.

  • Constipation might be alleviated by eating fiber-rich foods.

  • To manage dizziness, rise slowly from sitting or lying positions.

Use in Driving and Operating Machinery

  • This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness, blurred vision, sleepiness or drowsiness after taking this medicine.

Use in Pregnancy and Lactation

  • The safety of using Solifenacin + Tamsulosin during pregnancy and lactation has not been established. It is advised to consult your doctor before taking this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Individuals with liver or kidney conditions should use Solifenacin + Tamsulosin with caution. Monitoring by a doctor may be necessary due to potential health risks associated with these organs.

Special Dietary and Lifestyle Recommendations

  • Increase fluid intake unless otherwise advised by your doctor, to help manage dry mouth and constipation.

  • Incorporate a high-fibre diet to help alleviate constipation often caused by this medication.

  • Practice cautious movements from lying or seated positions to standing to minimize the risk of dizziness from sudden changes in blood pressure. This dietary adjustment helps manage blood pressure while on this medication.

  • Maintain a cool environment when possible, as Solifenacin + Tamsulosin can increase heat sensitivity.

Frequently asked questions

No, Solifenacin + Tamsulosin is not a steroid. It is a combination medicine used to manage benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged.

Solifenacin + Tamsulosin may cause drowsiness as one of its side effects. If you experience this, it is advisable to avoid activities that require alertness such as driving until you know how the medicine affects you.

Solifenacin and Tamsulosin are not typically associated with affecting fertility. Solifenacin is used for overactive bladder, and Tamsulosin is used for benign prostatic hyperplasia. However, if you have specific concerns about how these medications might impact your fertility, it's best to discuss them with your doctor.

You should avoid consuming grapefruit or grapefruit juice while taking this medication as it can increase the levels of Solifenacin in your body, potentially leading to increased side effects.

The safety of daily intake of Solifenacin + Tamsulosin depends on your individual health condition and the doctor's recommendation. Always follow your doctor's instructions regarding dosage and duration.

You may notice some improvement within the first week of taking Solifenacin + Tamsulosin, but full benefits are usually seen after about 4 weeks of consistent use.

The best time to take Solifenacin + Tamsulosin is as recommended by your doctor. The medication can be taken with or without food as per the doctor's instructions.

Terms & Conditions


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