Strontium

Dosage Forms Available

• Strontium is available in various forms depending on its medical application. For treating cancer-related bone pain, strontium-89 chloride is used as an injection.

• The route of administration for strontium-89 injection is intravenous, meaning it is infused directly into a vein.

• Strontium ranelate, used for osteoporosis, comes in a powder form that is mixed with water to create an oral suspension.

Age and Dose Restrictions

• Strontium ranelate is intended for use in adults only. Specifically, it is indicated for postmenopausal women and adult men who are at high risk of fractures.

Contraindications

• This medicine is contraindicated in patients with severe kidney disease.

• It is also contraindicated in individuals with a history of blood clots or those who are immobile.

Other Medications to Avoid

• This medicine can interact with chemotherapy agents (such as doxorubicin and cyclophosphamide), radiotherapy treatments, and minerals (like calcium and magnesium supplements).

• Before starting any new medications, including over-the-counter choices or supplements, consulting a doctor is essential.

Overdose and Missed Dose

• An overdose of strontium can lead to abnormal heart rhythms and nervous system issues. Medical attention should be sought immediately if overdose is suspected.

• If a dose of strontium ranelate is missed, it should be taken as soon as remembered if it is still within 12 hours of the scheduled time. If more than 12 hours have passed, skip the missed dose and continue with the next scheduled dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea, consider taking the medication with a light snack or before bedtime.

• For diarrhea, ensure adequate hydration by drinking plenty of fluids.

Use in Driving and Operating Machinery

• Strontium ranelate may cause dizziness or headaches in some individuals, which could affect their ability to drive or operate heavy machinery. Caution should be exercised until you know how the medicine affects you.

Use in Pregnancy and Lactation

• Strontium ranelate is not recommended for use during pregnancy or breastfeeding. Safety in these conditions has not been established.

• Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

• Caution is advised when using strontium ranelate in individuals with current or past history of skin reactions.

• Those with abnormal bone growths should also use this medicine cautiously under medical supervision.

Special Dietary and Lifestyle Recommendations

• Individuals using strontium for osteoporosis should ensure adequate dietary calcium intake but avoid taking calcium supplements within two hours of strontium to avoid interference with absorption.

• A balanced diet rich in vitamin D, through exposure to sunlight and consuming vitamin D-rich foods like fatty fish and fortified cereals, can enhance overall bone health.

• Regular weight-bearing exercises such as walking, jogging, or yoga can help strengthen bones and improve mobility.