Terbinafine
ANTIFUNGALUses of Terbinafine
- Terbinafine is an antifungal medication used to treat various fungal infections. It is effective in treating fungal infections of the scalp, body, groin (jock itch), feet (athlete's foot), toenails, and fingernails.
- It helps reduce symptoms such as itching, burning, redness, and scaling, providing relief from the discomfort caused by these infections.
Side effects of Terbinafine
The side effects of Terbinafine are:
- Loss of appetite
- Stomach pain
- Feeling bloated or sick
- Diarrhoea
- Indigestion
- Headache
- Itching
- Joint and muscle pain
How Terbinafine works
- Terbinafine works by inhibiting the enzyme squalene monooxygenase, which is crucial for the synthesis of ergosterol, a key component of fungal cell membranes.
- Ergosterol is essential for maintaining the integrity and function of the fungal cell wall. By inhibiting this enzyme, terbinafine prevents the formation of ergosterol, leading to an accumulation of squalene, which is toxic to fungal cells.
- The lack of ergosterol results in the disruption of the cell membrane, causing cell death and effectively stopping the growth and multiplication of fungi. This action leads to the resolution of fungal infections.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Teribnafine can be taken orally (tablet) and applied topically (cream).
Age and Dose Restrictions
- It is intended to be used by adults and children above two years of age.
Contraindications
- It is contraindicated in patients with a history of hypersensitivity to Terbinafine. It is also contraindicated in patients with facial rashes, psoriasis, liver disease, kidney disease, joint pain, muscle disorder, cutaneous and systemic lupus erythematosus.
Other Medications To Avoid With This Medicine
- Avoid taking antimicrobials (rifampicin), H2 blockers (cimetidine), immunosuppressants (cyclosporine), tricyclic antidepressants (despiramine), oral contraceptives (ethinylestradiol), other antifungals (ketoconazole), beta-blockers (metoprolol), and anttitussives (dextromethorphan). These medications may alter the safety and effectiveness of Terbinafine.
Overdose and Missed Dose
- Overdose can cause headache, stomach pain, feeling sick, or dizziness. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
- If you miss a dose of Terbinafine, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.
Use In Driving And Operating Machinery
- It may cause dizziness. Therefore, drive only if you alert after taking it.
Use in Pregnancy and Lactation
- It is not recommended during pregnancy and breastfeeding.
Caution In Other Conditions
- Caution is advised in older adults and patients with heart conditions.
Special Dietary & Lifestyle Recommendation
- Wash the affected area daily with mild soap and water, then thoroughly dry it.
- After showering or bathing, ensure you dry your skin completely, paying extra attention to the areas between toes or skin folds.
- Choose moisture-wicking fabrics for underwear and socks to help keep the affected areas dry.
- Tight clothing can trap moisture, creating an environment conducive to fungal growth. Opt for loose-fitting attire, especially in the affected areas.
- As your doctor recommends, apply antifungal powders or sprays to help keep the area dry and inhibit fungal growth.
- Do not share towels, socks, or other personal items that come into contact with the affected areas to prevent the spread of infection.
- Keep your feet clean and dry, especially between the toes.
- Change shoes and socks regularly, and allow your shoes to air out between uses.
Frequently asked questions
Is Terbinafine a steroid?
No, it is not a steroid. It belongs to the group of antifungal agents.
Is Terbinafine safe for children?
It is not recommended for children below two years of age.
How often should Terbinafine be taken?
The recommended dose of this medication should be taken as your doctor prescribes. The dosage may change based on individual factors such as age, severity of the condition, and response to treatment.
Is Terbinafine safe?
Yes, it is generally considered safe when used as prescribed by the doctor. However, like any medication, it may cause side effects in some individuals.
Can Terbinafine be safe for use in patients with liver cirrhosis?
Terbinafine is an antifungal medication used to treat fungal and yeast infections. Liver injury is a potential side effect, but liver failure is rare. Patients with liver diseases should consult doctor before taking this medicine.
Can I drink tea or coffee while taking Terbinafine?
There are no specific interactions between terbinafine and tea/coffee. However, it’s always best to consult your doctor to avoid food medicine interaction.
Does Terbinafine cause any skin reactions?
Terbinafine when applied topically as cream may cause skin irritation, itching, or blistering at the application site. Serious allergic reactions are rare but seek medical attention if you experience severe symptoms.
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