Vinorelbine

Dosage Forms Available

• Vinorelbine is available as an injectable solution.

• It is administered intravenously by a healthcare professional.

Age and Dose Restrictions

• This medicine is primarily meant for adults.

• The specific dosage varies according to the type of cancer being managed and the patient's overall health and response to therapy.

Contraindications

• This medicine is contraindicated for patients with known hypersensitivity to Vinorelbine or any of its components.

• It should not be given to patients with severe bone marrow suppression.

Other Medications to Avoid

• Vinorelbine may interact with several medications, including antifungal medicines like ketoconazole, antibiotics such as erythromycin, and anticonvulsants like phenytoin. It can also interact with anticancer agents such as cisplatin or doxorubicin, calcium channel blockers like diltiazem, and immunosuppressants such as cyclosporine.

Overdose and Missed Dose

• If you suspect an overdose of Vinorelbine, contact your healthcare provider immediately. An overdose may cause severe side effects like bone marrow suppression leading to infections, bleeding or fatigue.

• If you miss a dose, contact your doctor right away for instructions. Do not double up on the next dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To reduce nausea and vomiting, try taking small frequent meals. Drink plenty of fluids to prevent dehydration.

• Try resting more if you experience fatigue or weakness.

• Proper oral hygiene can help manage mouth sores.

Use in Driving and Operating Machinery

• Vinorelbine may cause fatigue and weakness which can affect your ability to drive or operate machinery.

• Avoid driving or operating heavy machinery if you experience these side effects.

Use in Pregnancy and Lactation

• It is not recommended to use Vinorelbine during pregnancy as it may cause harm to the developing baby.

• Breastfeeding mothers should also avoid this medicine as it may pass into breast milk.

Caution in Other Conditions

• Use of Vinorelbine should be done with caution in patients with liver or kidney disease.

• It should also be used cautiously in patients with existing bone marrow suppression.

Special Dietary and Lifestyle Recommendations

• Eat a well-balanced diet rich in proteins, fruits, vegetables, and whole grains to help maintain your strength and immunity during cancer treatment.

• Avoid consuming alcohol as it can potentially aggravate the side effects of Vinorelbine.

• Rest and relaxation techniques such as meditation can help manage stress and fatigue associated with cancer treatment.