Aqsusten 50 Mg Injection 1

Aqsusten 50 Injection 2.237ml

Sun Pharmaceutical Industries Ltd

Vial of 2.237 ML

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MRP ~~₹212.00~~

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Composition

Natural Micronised Progesterone (50 Mg)

Aqsusten 50 Injection is primarily used for supplementing and replacing progesterone, a vital hormone in various gynaecological and obstetric conditions. This medication falls in the category of progestin.

In addition to this main use, this injection also supports the luteal phase in infertility treatments like in-vitro fertilisation, helps manage dysfunctional uterine bleeding and secondary amenorrhoea due to progesterone deficiency, and is an essential part of hormone replacement therapy for managing symptoms of menopause.

Before starting this medicine, it's important to consult your doctor about the appropriate dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications you're taking. On experiencing any side effects while on this medication, immediately let your doctor know. For optimal results, continue taking the medicine for the entire duration prescribed by your doctor.

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Aqsusten 50 Injection is used for the following:

Supporting the luteal phase during fertility treatment
Management of threatened or recurrent miscarriages related to progesterone deficiency
Controlling irregular uterine bleeding and secondary amenorrhea due to a lack of progesterone.
Used alongside estrogens in hormone replacement therapy for menopause symptoms.

Directions for Use of Aqsusten 50 Injection 2.237ml

Administer Aqsusten 50 Injection as follows:

The medicine is administered via an intramuscular injection.
Ensure the area of injection is clean before administering the medicine.
The medicine should be administered by a trained healthcare professional.
For any specific information or concerns, it's recommended to consult your doctor.

Aqsusten 50 Injection is administered via an intramuscular route.

Side Effects of Aqsusten 50 Injection 2.237ml

Aqsusten 50 Injection might have the following common side effects:

Injection site reactions: This can include pain, swelling, or redness at the spot where the injection was administered.
Breast tenderness or enlargement
Headache
Dizziness
Nausea and abdominal cramps: You may experience discomfort in your stomach area, along with a feeling of wanting to vomit.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Aqsusten 50 Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and abdominal cramps: Try lying down and avoid consuming heavy meals until the feeling subsides.
Dizziness: Avoid sudden movements and try to sit or lie down when you feel dizzy.

How Aqsusten 50 Injection 2.237ml Works?

Aqsusten 50 Injection contains progesterone (50 mg) which works on your body as follows:

Uterus Preparation: Progesterone transforms the proliferative endometrium into a secretory one, preparing it for blastocyst implantation.
Pregnancy Maintenance: By suppressing myometrial contractility, progesterone promotes uterine quiescence, which is crucial for maintaining pregnancy.
Immune Response Modulation: Progesterone modulates immune responses, allowing maternal immune tolerance to the embryo.
Early Embryonic Development Support: Progesterone supports early embryonic development until the placenta takes over production.

Pregnancy

Caution is advised while administering Aqsusten 50 Injection if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

If you are breastfeeding, it's crucial to discuss the benefits and risks of Aqsusten 50 Injection with your doctor before starting this medicine.

Alcohol

The interaction of Aqsusten 50 Injection with alcohol is unknown. Please consult your doctor about consuming alcohol while receiving this medicine.

Liver

If you have mild to moderate liver health issues, please use Aqsusten 50 Injection with caution. This medicine is not recommended if you have severe liver disease. Discuss your health concerns with your doctor prior to starting this medicine.

Kidney

Before administering Aqsusten 50 Injection, it's advisable to consult your doctor if you have a history of kidney problems.

Using Machines & Driving

Aqsusten 50 Injection can cause dizziness or drowsiness. Hence, avoid driving or operating heavy machinery after administering this medicine.

Allergy

This medicine should not be used if you are hypersensitive to progesterone or any other ingredients in the formulation. If you experience allergic reactions, stop using Aqsusten 50 Injection and promptly consult your doctor.

Children

Aqsusten 50 Injection is meant for adult use. Always consult your doctor before giving any medicine to children under 18 years of age.

Older Patients

Older patients may be more susceptible to side effects of Aqsusten 50 Injection and should administer it under medical supervision. Your doctor will guide you based on your health status.

Interactions of Aqsusten 50 Injection 2.237ml

Drug-Drug Interactions

Aqsusten 50 Injection interacts with the following medicines:

CYP3A4 Inhibitors: Medicines like ketoconazole and erythromycin may increase progesterone levels when administered alongside Aqsusten 50 Injection.
CYP3A4 Inducers: Certain medications, such as rifampin and carbamazepine, can decrease progesterone levels when given in combination with this injection.

Drug-Food Interactions

No specific food interactions have been reported for Aqsusten 50 Injection.

Drug-Disease Interactions

Aqsusten 50 Injection interacts with the following diseases:

Liver Disease: Individuals with severe liver impairment should avoid using this injection as it could worsen their condition.
Breast or Genital Tract Cancers: People suffering from breast or genital tract cancers should not use this medicine due to potential risks.
Cardiovascular Disorders: Those with cardiovascular disorders should exercise caution when using this injection as it might complicate their condition.
Thrombophlebitis: Patients with a history of arterial or severe thrombophlebitis should avoid using Aqsusten 50 Injection.

Daily Dose

The daily dosage of Aqsusten 50 Injection should be administered as directed by your doctor. The dosage may vary based on factors like the severity of your condition and how you respond to the medicine. Remember, it's crucial to stick to the prescribed dosage and not alter it without consulting your doctor.

Over Dose

In the event of an overdose of Aqsusten 50 Injection, you might experience excessive sleepiness, dizziness, and vaginal bleeding. If these symptoms persist or worsen, it's important to inform your doctor.

Missed Dose

If you forget to administer a dose of Aqsusten 50 Injection as scheduled, do it as soon as you remember. However, if it's almost time for your next dose, skip the one you missed and continue with your regular schedule. Do not double the dose. Always consult your doctor before altering your dosage in any way.

Store Aqsusten 50 Injection at a controlled room temperature below 30°C.
Keep it well protected from light and do not expose it to freezing conditions.
Keep this medicine out of the reach of children.
Use this medicine immediately after opening the vial and discard the unused portion.

Maintaining a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can support overall reproductive health if you're undergoing infertility treatment.
For those managing menopause symptoms, regular physical activity may help reduce hot flashes and mood changes.

Fact Box

Drug Category	Progesterone receptor agonist
Therapeutic Category	Progestogen
Available Dosage Types	Injection
Habit Forming	No
Ailment	Infertility, Miscarriage, Amenorrhoea

What exactly is an Aqsusten 50 Injection?

Aqsusten 50 Injection is an injectable medication containing natural micronized progesterone, a hormone vital for female reproductive health.

What are the primary uses of Aqsusten 50 Injection?

This medicine is used for supporting fertility treatments, managing recurrent miscarriages, correcting menstrual irregularities due to progesterone deficiency, and in hormone replacement therapy.

How does Aqsusten 50 Injection work?

Progesterone in Aqsusten 50 Injection binds with specific receptors in the body to regulate various reproductive functions like preparing the uterus for pregnancy and maintaining it.

Is it safe to use Aqsusten 50 Injection during breastfeeding?

Progesterone does pass into breast milk in small amounts. It's best to consult your doctor before using this medicine while breastfeeding.

Can I administer the Aqsusten 50 Injection myself?

Administering injections can be tricky and may require professional training. Always consult your doctor or a trained healthcare provider for injection procedures.

What should I do if I miss a dose of Aqsusten 50 Injection?

If you've missed a dose, administer it as soon as you remember. If it's nearly time for the next dose, skip the missed one and follow your regular schedule.

Are there any side effects associated with Aqsusten 50 Injection?

Common side effects include injection site reactions, breast tenderness, headache, dizziness, nausea, abdominal cramps, mood changes and weight gain. Consult your doctor if these persist.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

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Manufacturer details

SCO No. 14, Sector 5, Panchkula – 134114, Haryana

Country of origin: INDIA

References

Progesterone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00396
Progesterone: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a604017.html
DailyMed - CRINONE- progesterone gel. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2c8ffbd2-6b7a-42c7-b29e-e4de69dad9e6
Jewson, M., Purohit, P., & Lumsden, M. A. (2020). Progesterone and abnormal uterine bleeding/menstrual disorders. Baillière’s Best Practice & Research. Clinical Obstetrics & Gynaecology/Baillière’s Best Practice and Research in Clinical Obstetrics and Gynaecology, 69, 62–73. https://doi.org/10.1016/j.bpobgyn.2020.05.004
PubChem. (n.d.-d). Progesterone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/5994

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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