Artinex 80480 Mg Tablet 10

Artinex 80/480 MG Tablet 10

Senate Laboratories

Pack of 10 Units

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Composition

Artemether (80 Mg) + Lumefantrine (480 Mg)

Artinex 80/480 MG Tablet 10 is used to manage acute, uncomplicated malaria infections caused by the Plasmodium falciparum parasite. It is a combination medicine that belongs to antimalarial agents.

This tablet is particularly effective in cases where the parasite has developed resistance to other antimalarial medicines. However, it's not intended to prevent malaria or treat severe or complicated cases.

Before you start taking this medicine, consult your doctor about your dosage and timing. Be sure to notify them about any pre-existing conditions you have and any other medications you're currently on. If you experience any side effects while using this medication, inform your doctor promptly. It's important to use this medicine for the full duration prescribed by your doctor to ensure optimal results.

Artinex 80/480 MG Tablet 10 is used for the following:

Managing acute, uncomplicated malaria infections caused by Plasmodium falciparum: This is a specific type of malaria parasite that can lead to serious illness.
Combatting malaria in areas where the parasite has developed resistance to other antimalarial medicines: Sometimes, malaria parasites can become resistant to certain types of medication, and Artinex 80/480 MG Tablet 10 can be effective against these.

Directions for Use of Artinex 80/480 MG Tablet 10

Here are some simple guidelines on how to take Artinex 80/480 MG Tablet 10:

Swallow the whole tablet with a fat-containing drink, such as milk. This can help your body absorb the medicine better.
Avoid crushing or chewing the tablet. This could affect how well the medicine works.
Don't take more than your doctor has recommended. If you're unsure about how much to take, ask your doctor.
Ensure you complete the full course of medication, even if you start to feel better before it's finished. This helps to fully clear the infection from your body.

Artinex 80/480 MG Tablet 10 is taken orally.

Side Effects of Artinex 80/480 MG Tablet 10

Artinex 80/480 MG Tablet 10 may have the following common side effects:

Headache
Dizziness
Fatigue
Muscle pain
Joint pain
Cough
Nausea
Vomiting
Abdominal pain
Rash
Sleep disturbances
Decreased appetite or lack of desire to eat
Palpitations

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Artinex 80/480 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and Vomiting: Try taking Artinex 80/480 MG Tablet 10 with food or drinks containing fat, such as milk, for better absorption and to lessen the impact of these side effects.
Sleep Disturbances: If you find it hard to sleep after taking this medicine, consider adjusting your dosage schedule so that you take it earlier in the day.

Artinex 80/480 MG Tablet 10 contains two active ingredients:

Artemether (80 mg): Artemether acts swiftly and effectively to clear parasites from your blood. It targets a specific stage of the P. falciparum life cycle within red blood cells, which helps control the infection's spread.
Lumefantrine (480 mg): Lumefantrine works at a different stage of the parasite's life cycle, eliminating residual parasites and preventing recurrence, ensuring that no remaining parasites can trigger a new round of infection.
Together, these components work synergistically to inhibit the growth and reproduction of malarial parasites, managing the infection effectively.

Pregnancy

Artinex 80/480 MG Tablet 10 is not recommended during the first trimester of pregnancy unless the benefits outweigh the risks. If you are pregnant or planning to conceive, it's best to discuss this with your doctor before starting on this medicine.

Breastfeeding

Artinex 80/480 MG Tablet 10 is not recommended for breastfeeding women. Inform your doctor that you are breastfeeding if this medicine is prescribed to you.

Alcohol

It is advised not to consume alcohol if this medicine is prescribed to you to avoid any adverse effects.

Liver

Artinex 80/480 MG Tablet 10 is not recommended for those with severe liver diseases. If you have liver problems, it's advisable to discuss them with your doctor before starting this medication.

Kidney

In cases of severe kidney impairment, caution is advised while taking Artinex 80/480 MG Tablet 10. Consult your doctor if you have any kidney issues before taking this medicine.

Using Machines & Driving

This medicine could cause side effects like dizziness and fatigue, which may affect your ability to drive or operate machinery. Be cautious if these symptoms occur.

Allergy

Artinex 80/480 MG Tablet 10 is warned against use for anyone allergic to artemether or lumefantrine, or any other components of the tablet. Consult your doctor if you have known allergies before starting this medicine.

Children

Artinex 80/480 MG Tablet 10 can be given to children weighing 5 kg or more, as per a doctor's prescription. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Artinex 80/480 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Artinex 80/480 MG Tablet 10

Drug-Drug Interactions

Artinex 80/480 MG Tablet 10 can interact with the following medicines:

CYP3A4 inducers like rifampin, carbamazepine, phenytoin can decrease the efficacy of Artinex 80/480 MG Tablet 10.
Antiretrovirals like ritonavir used in HIV management can increase the concentrations of artemether and lumefantrine, leading to potential side effects.
Hormonal Contraceptives: The effectiveness of medicines like ethinylestradiol may be reduced when taken alongside Artinex 80/480 MG Tablet 10.

Drug-Food Interactions

The absorption and efficacy of Artinex 80/480 MG Tablet 10 are enhanced when it is taken with fatty foods or drinks like milk.

Drug-Disease Interactions

Artinex 80/480 MG Tablet 10 can interact with the following diseases:

Electrolyte Imbalances: Patients with conditions like hypokalaemia or hypomagnesemia should take precautions, as this can impact the QT interval.
Liver Disease: People with severe liver disease should avoid taking Artinex 80/480 MG Tablet 10 due to potential adverse effects.
Renal Impairment: This medicine is not advised for patients with severe kidney disease due ti its potential risk.

Daily Dose

The daily dose of Artinex 80/480 MG Tablet 10 should be taken as directed by your doctor. This may vary based on the severity of your condition and your response to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

Overdosing on Artinex 80/480 MG Tablet 10 could lead to symptoms such as dizziness, fatigue, and nausea. If you have accidentally taken more than the recommended dose, inform your doctor, especially if any symptoms persist or worsen.

Missed Dose

If you forget to take a dose of Artinex 80/480 MG Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without consulting your doctor.

Store your Artinex 80/480 MG Tablet 10 in its original packaging at room temperature.
Shield it from excessive heat and dampness.
Always place it out of the reach and sight of children.
Make sure you use this medicine before the expiry date marked on the pack.

Wear insect repellent or long-sleeved clothing, especially at dawn and dusk when mosquitoes are most active.
Include plenty of fruits, vegetables, and whole grains, which can help your body recover faster from a malaria infection.

Fact Box

Drug Category	Antimalarial Agents
Therapeutic Category	Antiparasitic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Acute Plasmodium falciparum malaria

What is Artinex 80/480 MG Tablet 10 used for?

It is a prescription medication used to manage acute, uncomplicated malaria caused by the Plasmodium falciparum parasite.

How does Artinex 80/480 MG Tablet 10 work against malaria?

This medicine contains artemether and lumefantrine, which work together to stop the growth and reproduction of the malarial parasite, effectively managing the infection.

Can Artinex 80/480 MG Tablet 10 be taken without food?

No, it should be taken with food or drinks high in fat, like milk, for better absorption of the active ingredients.

Is Artinex 80/480 MG Tablet 10 safe during pregnancy?

It is not recommended during the first trimester unless other treatment options are unavailable. Always consult your doctor first.

What should I do if I vomit after taking Artinex 80/480 MG Tablet 10?

If you vomit within an hour of taking the medicine, consult your doctor for the next dose or alternative medication.

Can Artinex 80/480 MG Tablet 10 cause any side effects?

Yes, common side effects include headache, dizziness, fatigue, muscle and joint pain, nausea, and vomiting. Consult your doctor if they persist or worsen.

Can I stop taking Artinex 80/480 MG Tablet 10 when my symptoms improve?

No, it's important to complete the full course even if symptoms improve earlier to prevent the recurrence of infection.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

SCF 36, 1ST FLOOR M.MARKET, MANIMAJRA, CHANDIGARH-160101

References

MedlinePlus. (n.d.). Artemether and Lumefantrine: MedlinePlus Drug Information. Retrieved from https://medlineplus.gov/druginfo/meds/a609024.html
U.S. Food and Drug Administration. (2018). Highlights of prescribing information. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/022268s019lbl.pdf
PubChem. (n.d.-g). Artemether. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Artemether
Artemether: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06697
PubChem. (n.d.-al). Lumefantrine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/lumefantrine
Lumefantrine: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06708

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