Cardinol Plus 5/50 MG Tablet 10

Hab Pharmaceuticals

Pack of 10 Units

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Composition

Amlodipine (5 Mg) + Atenolol (50 Mg)

Cardinol Plus 5/50 MG Tablet 10 is primarily used for managing high blood pressure, also known as hypertension. It is a combination medication that belongs to the category of antihypertensive medicines. This dual-action tablet helps maintain a healthy blood pressure level, promoting overall cardiovascular health.

This medicine also manages the associated symptoms of hypertension. It aids in reducing the risk of severe conditions such as heart attacks and strokes caused by prolonged hypertension. This medicine plays a vital role in maintaining a balanced blood flow and ensuring your body's vital organs receive sufficient oxygen and nutrients.

While taking this medicine, it's essential to follow your doctor's prescribed dosage and frequency. Inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while on this medicine, notify your doctor immediately. Take the tablet for the duration prescribed by your doctor for optimal results.

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Cardinol Plus 5/50 MG Tablet 10 is beneficial for managing the following conditions:

Lowering high blood pressure levels, also known as hypertension
Initial therapy for those likely to need multiple medicines to achieve their blood pressure goals
Add-on therapy for patients whose blood pressure is not adequately controlled with either amlodipine or atenolol alone

Directions for Use of Cardinol Plus 5/50 MG Tablet 10

To use Cardinol Plus 5/50 MG Tablet 10 correctly, follow these instructions:

Swallow the tablet whole with water.
The tablet can be taken with or without food.
Always take this medicine exactly as your doctor has advised.
It's important not to stop taking this medicine without consulting your doctor first.

Cardinol Plus 5/50 MG Tablet 10 is taken orally.

Side Effects of Cardinol Plus 5/50 MG Tablet 10

Cardinol Plus 5/50 MG Tablet 10 might have the following common side effects:

Fatigue
Dizziness
Nausea
Diarrhoea
Constipation
Shortness of breath
Hypotension, or low blood pressure
Peripheral oedema, that is swelling of ankles and feet

Managing the Side Effects:

Most side effects are temporary, generally mild, and resolve upon stopping the use of Cardinol Plus 5/50 MG Tablet 10. However, if you experience serious side effects or worsening of any symptoms, consult your doctor.

Here are a couple of tips on how to manage some common side effects:

Nausea and diarrhoea: Try taking Cardinol Plus 5/50 MG Tablet 10 with food to reduce stomach upset.
Dizziness: Consider taking this medicine at bedtime to reduce daytime dizziness.

How Cardinol Plus 5/50 MG Tablet 10 Works?

Cardinol Plus 5/50 MG Tablet 10 is composed of two active ingredients:

Amlodipine (5 mg): This ingredient falls under the category of calcium channel blockers. Its primary action is restricting the movement of calcium ions into the heart and vascular smooth muscle cells. By doing so, it helps widen your blood vessels and improve the supply of blood and oxygen to your heart. This action effectively lowers high blood pressure.
Atenolol (50 mg): As a beta blocker, atenolol specifically targets beta-1-adrenergic receptors in your heart and vascular smooth muscle. By blocking these receptors, it reduces the effects of chemicals that can increase heart rate and blood pressure. This action helps slow down your heart rate and decrease blood pressure.

These combined mechanisms contribute effectively to managing hypertension by reducing both peripheral resistance and cardiac output.

Pregnancy

Caution is advised while taking Cardinol Plus 5/50 MG Tablet 10 if you are pregnant. Consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, discuss this with your doctor before starting Cardinol Plus 5/50 MG Tablet 10.

Alcohol

While on Cardinol Plus 5/50 MG Tablet 10, avoid consuming alcohol as it may intensify some side effects of the medication.

Liver

Cardinol Plus 5/50 MG Tablet 10 should be used with caution if you have liver issues. Since amlodipine undergoes extensive metabolism in the liver, consultation with your doctor is advised.

Kidney

Be cautious if you have a history of kidney problems. Atenolol, one of the components of this medicine, is excreted via the kidneys therefore, prior consultation with your doctor is advised.

Using Machines & Driving

Since dizziness can occur while taking Cardinol Plus 5/50 MG Tablet 10, caution is advised when driving or operating machinery.

Allergy

If you have known allergies to amlodipine, atenolol or any other component of the formulation, avoid taking this medicine.

Children

Cardinol Plus 5/50 MG Tablet 10 is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Cardinol Plus 5/50 MG Tablet 10 under medical supervision. They might be more susceptible to its side effects.

Interactions of Cardinol Plus 5/50 MG Tablet 10

Drug-Drug Interactions

Cardinol Plus 5/50 MG Tablet 10 interacts with these medicines:

Antihypertensives: Other blood pressure-reducing medicines like prazosin or terazosin may interact with Cardinol Plus 5/50 MG Tablet 10, potentially leading to extremely low blood pressure.
Non-Steroidal Anti-Inflammatory Medication (NSAIDs): Medicines such as ibuprofen or naproxen may decrease the blood pressure-lowering effect of atenolol in this medicine.
Cardiac glycosides: Medicines like digoxin may interact with Cardinol Plus 5/50 MG Tablet 10, increasing the risk of slow heart rate.
CYP3A4 inhibitors: Medicines such as erythromycin or clarithromycin may increase the level of amlodipine in your body and possibly increase the side effects.

Drug-Food Interactions

Cardinol Plus 5/50 MG Tablet 10 interacts with the following foods:

Grapefruit juice: Drinking grapefruit juice while taking this medicine might increase amlodipine levels in your body.

Drug-Disease Interactions

Cardinol Plus 5/50 MG Tablet 10 interacts with the following diseases:

Diabetes: This medicine can mask symptoms of low blood sugar (hypoglycaemia) and also prolong hypoglycaemic episodes, so exercise caution if you have diabetes.
Liver disease: Patients with severe liver disease should be cautious as amlodipine is metabolised in the liver.
Kidney disease: One of the active ingredients, atenolol, is excreted through the kidneys. If you have kidney problems, use this medicine carefully.

Dosage of Cardinol Plus 5/50 MG Tablet 10

Daily Dose

Take your daily dose of Cardinol Plus 5/50 MG Tablet 10 as instructed by your doctor. Your dosage might be adjusted according to your response to the medicine and the severity of your condition. Always adhere to the prescribed dosage and never increase it without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Cardinol Plus 5/50 MG Tablet 10, you may experience common side effects like dizziness or fatigue in a more pronounced manner. If such symptoms persist or worsen, inform your doctor.

Missed Dose

In case you miss a regular dose of Cardinol Plus 5/50 MG Tablet 10, take it when you remember. But if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Don't adjust your dosage without consulting with your doctor.

Store Cardinol Plus 5/50 MG Tablet 10 in a cool, dry place at room temperature.
Avoid exposure to light and moisture.
Keep the medicine out of reach of children.
Always check the expiration date on the package before use.

Since this medicine is used to manage high blood pressure, reducing your salt intake can help control hypertension.
Engage in moderate physical activity, like walking or cycling, to help lower blood pressure by strengthening your heart and making it more efficient at pumping blood.

Fact Box

Drug Category	Calcium Channel Blocker, Beta-1 Receptor Antagonist
Therapeutic Category	Antihypertensives
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension

What is Cardinol Plus 5/50 MG Tablet 10 used for?

This medicine is used to manage hypertension (high blood pressure), helping to reduce the risk of strokes and heart attacks.

How does Cardinol Plus 5/50 MG Tablet 10 work?

It contains two active ingredients, amlodipine and atenolol. Amlodipine relaxes blood vessels, while atenolol reduces heart rate, together lowering blood pressure.

Can I take this medicine with or without food?

You can take Cardinol Plus 5/50 MG Tablet 10 either with or without food.

Who should not take Cardinol Plus 5/50 MG Tablet 10?

Individuals with conditions like bradycardia, severe hypotension, uncontrolled heart failure or known hypersensitivity to its components should not use this medicine.

What are some side effects of Cardinol Plus 5/50 MG Tablet 10?

Common side effects may include fatigue, dizziness, low blood pressure, nausea, and diarrhoea.

Can I stop taking this medicine suddenly?

No, stopping this medicine abruptly may cause adverse effects. If you wish to discontinue it, consult your doctor.

Are there any specific precautions while using this medicine?

Caution is advised for diabetic patients and those with impaired kidneys or liver. Always consult your doctor for personalised advice.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

References

U.S. Food and Drug Administration. (2007, Sep). Amlodipine tablets label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/022026lbl.pdf
U.S. Food and Drug Administration. (2011, Jul). Tenormin tablets label. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018240s031lbl.pdf
National Center for Biotechnology Information (2024). PubChem compound summary for CID 2162, amlodipine. https://pubchem.ncbi.nlm.nih.gov/compound/Amlodipine
National Center for Biotechnology Information (2024). PubChem compound summary for CID 2249, atenolol. https://pubchem.ncbi.nlm.nih.gov/compound/Atenolol
DrugBank Online. (2024, May 28). Amlodipine. https://go.drugbank.com/drugs/DB00381
DrugBank Online. (2024, May 28). Atenolol. https://go.drugbank.com/drugs/DB00335
National Health Service. (n.d.). Amlodipine. https://www.nhs.uk/medicines/amlodipine/
National Health Service. (n.d.). Atenolol. https://www.nhs.uk/medicines/atenolol/

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