Cefsafe 500 Mg Tablet 10

Cefsafe 500 Tablet 10

Khandelwal Laboratories Ltd

STRIP of 10 Units
Pack of 4 Units

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MRP ~~₹349.57~~

₹286.65

₹34.96/Units

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Composition

Cefuroxime (500 Mg)

Strength:

500 MG 250 MG

Cefsafe 500 Tablet 10 is primarily used to manage a variety of bacterial infections. This medicine belongs to the category of antibiotics known as cephalosporins.

This medication is also used to manage respiratory tract infections such as bronchitis and sinusitis, ear infections, skin and soft tissue infections, urinary tract infections, Lyme disease, and gonorrhoea.

Before you start taking this medicine, consult your doctor for the correct dosage and frequency based on your health condition and response to treatment. Also, inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Cefsafe 500 Tablet 10 is used for the following:

Managing respiratory tract infections like bronchitis, sinusitis, and tonsillitis
Controlling ear infections, specifically otitis media
Handling skin and soft tissue infections
Controlling urinary tract infections
Taking care of Lyme disease
Keeping gonorrhoea in check

Directions for Use of Cefsafe 500 Tablet 10

Swallow the tablet as a whole with a glass of water.
The tablet should not be crushed or chewed.
Taking this medicine with food is crucial to improve absorption and minimise side effects.
Always consult your doctor before making any changes to your medicine schedule.

Cefsafe 500 Tablet 10 is taken orally.

Cefsafe 500 Tablet 10 may cause the following side effects:

Nausea
Vomiting
Diarrhoea
Abdominal Pain
Dizziness
Drowsiness

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when the use of Cefsafe 500 Tablet 10 is discontinued. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Cefsafe 500 Tablet 10 contains cefuroxime (500 mg), which works in the body as follows:

Hydrolysis into Active Form: After oral administration, cefuroxime is rapidly converted into its active form by enzymes in your intestines and blood.
Inhibition of Cell Wall Synthesis: Cefuroxime works by inhibiting the synthesis of bacterial cell walls. This disruption causes the bacteria to die, helping to clear up the infection.
Stability against Beta-lactamases: Cefuroxime shows stability against many bacterial beta-lactamases. These are enzymes that can destroy many other antibiotics before they can take effect. This stability enhances cefuroxime's effectiveness in managing bacterial infections.

Pregnancy

Caution is advised while taking Cefsafe 500 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Cefsafe 500 Tablet 10 passes into the breast milk. If you are breastfeeding, it's important to consult your doctor before starting this medicine.

Alcohol

The interaction of Cefsafe 500 Tablet 10 with alcohol may lead to drowsiness or dizziness. It's advisable to limit your alcohol intake while on this medication.

Liver

If you have a history of liver problems, caution is recommended when taking Cefsafe 500 Tablet 10. This medicine may affect liver function, so it's important to discuss your liver health with your doctor before starting this medication.

Kidney

Cefsafe 500 Tablet 10 should be used with caution if you have kidney issues. Your doctor may need to adjust the dosage based on your kidney health.

Using Machines & Driving

This medicine might cause dizziness or drowsiness. Avoid driving or using heavy machinery until you know how Cefsafe 500 Tablet 10 affects you.

Allergy

If you are allergic to cefuroxime or other cephalosporins, do not take Cefsafe 500 Tablet 10. Before starting this medication, discuss any allergies with your doctor.

Children

Cefsafe 500 Tablet 10 is typically not recommended for children under 12 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Cefsafe 500 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Cefsafe 500 Tablet 10 may interact with the following medicines:

Gout medications like probenecid can increase the blood levels of Cefsafe 500 Tablet 10, possibly leading to more side effects.
Oral contraceptives: Cefsafe 500 Tablet 10 may reduce the effectiveness of birth control pills, increasing the risk of unwanted pregnancy.
Antacids containing magnesium or aluminium can decrease the absorption of Cefsafe 500 Tablet 10, reducing its effectiveness.
Certain diabetes medications: Cefsafe 500 Tablet 10 may cause false-positive urine glucose tests. Effect of medications like metformin and gliclazide may be affected.

Drug-Food Interactions

Food interactions with Cefsafe 500 Tablet 10 are not significant. However, to enhance absorption and minimise gastrointestinal side effects, it's recommended that this medicine be taken with food.

Drug-Disease Interactions

Cefsafe 500 Tablet 10 can interact with the following diseases:

Gastrointestinal diseases: If you have a history of conditions like colitis, caution is advised as this medicine could trigger severe diarrhoea.
Kidney disease: The dosage of Cefsafe 500 Tablet 10 may need adjusting in patients with impaired kidney function.
Liver disease: Patients with liver problems should use this medicine cautiously as it can exacerbate their condition.

Daily Dose

Your doctor will advise you on how often you should take Cefsafe 500 Tablet 10. This can vary based on factors like the severity of your condition and how you respond to the medicine. Always stick to the dosage your doctor prescribes. For further details, read the package insert.

Over Dose

If you inadvertently take more Cefsafe 500 Tablet 10 than recommended, you might experience symptoms such as nausea, vomiting, or dizziness. If these become severe or persist, consult your doctor.

Missed Dose

If you forget to take your Cefsafe 500 Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Cefsafe 500 Tablet 10 at room temperature, ideally around 25°C.
Keep the medicine away from direct light and moisture.
Ensure the tablet is well-sealed in its original packaging.
Always keep this medication out of reach of children.
Please check the expiry date before use and refrain from using it if it has expired.

If you're managing a urinary tract infection with Cefsafe 500 Tablet 10, ensure you drink plenty of water. This helps flush bacteria out of your urinary system.
Maintaining good personal hygiene is crucial for those with skin infections. Wash your hands regularly and keep the infected area clean to prevent the infection from spreading.

Fact Box

Drug Category	Antibiotic
Therapeutic Category	Antibacterial
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Respiratory tract infections, Urinary tract infections, Lyme disease

What type of infections does Cefsafe 500 Tablet 10 manage?

Cefsafe 500 Tablet 10 manages a variety of bacterial infections like respiratory tract, ear, skin, urinary tract infections, Lyme disease and gonorrhoea.

Is it safe to drive or operate machinery after taking Cefsafe 500 Tablet 10?

If dizziness or drowsiness occurs after taking the medicine, avoid driving or operating machinery until you are sure these effects have passed.

Can I stop taking Cefsafe 500 Tablet 10 once I feel better?

No, always complete the full course prescribed by your doctor to ensure complete management of the infection and prevent relapse.

What should I do if I miss a dose of Cefsafe 500 Tablet 10?

Take the missed dose as soon as you remember. If it's nearly time for your next dose, skip the missed one and resume your regular schedule.

Does Cefsafe 500 Tablet 10 interact with any other medications?

Yes, therefore, it is wise to inform your doctor about all other medications you're taking. Cefsafe 500 Tablet 10 can interact with certain medicines like probenecid and oral contraceptives.

Is it safe to consume alcohol while taking Cefsafe 500 Tablet 10?

Alcohol may increase side effects like dizziness and drowsiness. It's best to consult your doctor on this matter.

Can pregnant or breastfeeding women take Cefsafe 500 Tablet 10?

Cefuroxime passes into breast milk and should be used with caution during pregnancy. Always consult your doctor before starting any medication if you're pregnant or breastfeeding.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 7 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

References

U.S. National Library of Medicine. (2022, February 15). Cefuroxime. MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a601206.html
Cefuroxime: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01112
U.S. Food and Drug Administration. (2007). Label: Cefuroxime- cefuroxime axetil tablet, film coated. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050605s042lbl.pdf
Brogden, R., Heel, R., Speight, T., & Avery, G. (1979, April 1). Cefuroxime. Drugs. https://doi.org/10.2165/00003495-197917040-00001
Cefuroxime: antimicrobial activity, Pharmacology, and clinical efficacy. (1983, June 1). PubMed. https://pubmed.ncbi.nlm.nih.gov/6349019/
NHS. (2023, April 12). Cefalexin: Antibiotic used for infections such as pneumonia. nhs.uk. https://www.nhs.uk/medicines/cefalexin/

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