Clovis P 50325 Mg Tablet 10

Clovis P 50/325 MG Tablet 10

Dolvis Bio Pharma Pvt Ltd

Pack of 10 Units

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Composition

Diclofenac (50 Mg) + Paracetamol/acetaminophen (325 Mg)

Clovis P 50/325 MG Tablet 10 is primarily used to manage acute pain and inflammation associated with various conditions. This combination medicine belongs to a class of medications known as nonsteroidal anti-inflammatory drugs (NSAIDs) and analgesics.

Besides its primary use, this tablet is also effective in relieving discomfort caused by headaches, toothaches, menstrual cramps, muscle aches, and arthritis. It offers symptomatic relief from pain in these conditions, making it useful for managing different types of acute pain.

Before you start taking this medicine, remember to consult your doctor for the correct dosage and frequency. It's crucial to inform your doctor about any pre-existing conditions or ongoing medications you are on. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Clovis P 50/325 MG Tablet 10 is used for managing the following conditions:

Acute pain and inflammation associated with headaches, including migraines and tension headaches
Dental pain and discomfort after tooth extraction
Painful menstrual cramps, also known as dysmenorrhoea
Musculoskeletal discomfort such as sprains, strains, and backache
Post-operative and post-traumatic pain management
Pain and inflammation due to arthritis conditions, including osteoarthritis and rheumatoid arthritis

Directions for Use of Clovis P 50/325 MG Tablet 10

Here are some guidelines on how to take Clovis P 50/325 MG Tablet 10:

Swallow the tablet whole with some water.
Do not chew or crush the tablet.
It's best to take the medicine with or after meals.
Avoid taking more than your doctor's recommended dose.
Always consult your doctor before stopping this medicine.

Clovis P 50/325 MG Tablet 10 is taken orally.

Side Effects of Clovis P 50/325 MG Tablet 10

Clovis P 50/325 MG Tablet 10 may have the following side effects:

Abdominal pain
Nausea
Diarrhoea
Flatulence
Dizziness
Insomnia (trouble falling asleep or staying asleep)
Erythema (skin redness caused by increased blood flow to the skin surface)
Elevated liver enzymes (a potential issue with your liver function)

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Clovis P 50/325 MG Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Clovis P 50/325 MG Tablet 10 contains two active ingredients:

Diclofenac (50 mg): This ingredient is part of a group known as NSAIDs. It works by inhibiting enzymes called cyclooxygenase (COX) that are responsible for producing substances causing pain, inflammation, and fever in the body. By reducing these substances, diclofenac provides relief from these symptoms.
Paracetamol/Acetaminophen (325 mg): This is an analgesic and antipyretic component. It blocks pain impulses by inhibiting COX enzymes in the central nervous system. It also reduces fever by acting on the brain's heat-regulating center.
The combination of diclofenac and paracetamol in Clovis P 50/325 MG Tablet 10 effectively relieves acute pain and inflammation through their complementary mechanisms of action.

Pregnancy

Clovis P 50/325 MG Tablet 10 is warned against use during the third trimester of pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking this medicine if you are breastfeeding. It is best to consult your doctor to better understand any risks involved.

Alcohol

Combining alcohol and Clovis P 50/325 MG Tablet 10 might increase the risk of liver damage. It's recommended to limit your alcohol intake while taking this medicine.

Liver

Caution is advised while taking Clovis P 50/325 MG Tablet 10 in case of mild to moderate liver impairment. This medicine is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medication. The medicine may affect liver function.

Kidney

If you have a history of kidney problems, consult your doctor before taking Clovis P 50/325 MG Tablet 10. Special care might be needed in such cases.

Using Machines & Driving

Clovis P 50/325 MG Tablet 10 may cause side effects like dizziness or drowsiness that could affect your ability to drive or operate machinery. Avoid these activities if you experience such symptoms.

Allergy

Clovis P 50/325 MG Tablet 10 is not recommended if you have known allergies to diclofenac, paracetamol, or any other ingredients in the tablet. Discuss any past allergic reactions with your doctor before starting this medication.

Children

Clovis P 50/325 MG Tablet 10 is not recommended for use in children under 12 years of age due to a lack of safety and efficacy data. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Clovis P 50/325 MG Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age, as they might be on other medications. Your doctor will guide you based on your health status.

Interactions of Clovis P 50/325 MG Tablet 10

Drug-Drug Interactions

Clovis P 50/325 MG Tablet 10 interacts with the following medicines:

Anticoagulants such as warfarin or heparin when taken with diclofenac in Instagesic tablet may increase the risk of bleeding.
SSRIs (selective serotonin reuptake inhibitors) such as fluoxetine, which are anti-depressants, could interact with diclofenac, increasing the risk of stomach bleeding.
Anti-platelet medicines such as aspirin and clopidogrel might interact with diclofenac, leading to an increased risk of bleeding.
Anti-hypertensives (ACE inhibitors) like lisinopril or beta-blockers like atenolol may have their blood pressure-lowering effects reduced by diclofenac.
Nephrotoxic Medications: Diclofenac could potentially increase the risk of kidney damage when taken with cyclosporine or tacrolimus.
Hepatotoxic medications: When taken with other liver-damaging medications or alcohol, paracetamol in Clovis P 50/325 MG Tablet 10 can increase the risk of liver toxicity.

Drug-Food Interactions

Clovis P 50/325 MG Tablet 10 doesn't have any specific known food interactions.

Drug-Disease Interactions

Clovis P 50/325 MG Tablet 10 interacts with the following diseases:

Heart Disease: The diclofenac component may increase the risk of heart attack or stroke in people with pre-existing heart conditions.
Peptic Ulceration or Gastrointestinal Bleeding: Clovis P 50/325 MG Tablet 10 can worsen these conditions due to its diclofenac content.
Liver Disease: Paracetamol in this medicine can potentially exacerbate liver disease.
Renal Failure: This tablet should be used cautiously in patients with kidney disease as both diclofenac and paracetamol can affect kidney function.
Asthma: Patients with aspirin-sensitive asthma could have an allergic reaction to diclofenac in this tablet.

Daily Dose

The dose of this medicine should be as prescribed by your doctor. The dosage can vary based on the severity of your condition and your response to the medicine. Always stick to the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, please refer to the package insert.

Over Dose

If you accidentally take more than the prescribed dose, you might experience symptoms like nausea, dizziness, and abdominal pain. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take a dose of your medication, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Clovis P 50/325 MG Tablet 10 at room temperature, ideally between 15-30°C.
Keep the medicine in a dry place, away from light and moisture.
You should not expose the medicine to extreme heat or cold.
Always keep this medicine out of reach of children for safety.
Remember to use Clovis P 50/325 MG Tablet 10 before its expiry date.

If you're managing conditions like arthritis or toothache with Clovis P 50/325 MG Tablet 10, consider including omega-3 rich foods like fish and walnuts in your diet. These can help reduce inflammation and enhance the effectiveness of the medicine.
Regular low-impact exercises such as swimming or cycling can be beneficial for people living with musculoskeletal pain or arthritis. Physical activity helps keep your joints flexible and could potentially decrease your pain levels.

Fact Box

Drug Category	COX inhibitor
Therapeutic Category	Analgesic/antipyretic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Headache, Dental pain, Arthritis

What is Clovis P 50/325 MG Tablet 10 used for?

Clovis P 50/325 MG Tablet 10 is used to manage acute pain and inflammation in conditions such as headaches, dental pain, menstrual cramps, muscle aches, and arthritis.

How does Clovis P 50/325 MG Tablet 10 work?

Clovis P 50/325 MG Tablet 10 contains diclofenac and paracetamol, which work together to decrease pain and inflammation by reducing the production of certain chemicals in the body.

Can I take Clovis P 50/325 MG Tablet 10 if I have a peptic ulcer?

No, Clovis P 50/325 MG Tablet 10 is not advisable if you have active peptic ulceration or gastrointestinal bleeding. Always consult your doctor before taking any medication.

Could there be any side effects with Clovis P 50/325 MG Tablet 10?

Yes, some common side effects can include abdominal pain, dizziness, headache, rash, and elevated liver enzymes. If you experience any adverse effects, consult your doctor promptly.

Is it safe to take Clovis P 50/325 MG Tablet 10 during pregnancy?

It's best to avoid taking Clovis P 50/325 MG Tablet 10 during pregnancy, particularly in the third trimester. Please consult your doctor for advice appropriate to your situation.

Can I drink alcohol while taking Clovis P 50/325 MG Tablet 10?

Paracetamol in Clovis P 50/325 MG Tablet 10 may increase the risk of liver damage when combined with alcohol. It's advisable to limit or avoid alcohol consumption while on this medication.

How should I store Clovis P 50/325 MG Tablet 10?

Store Clovis P 50/325 MG Tablet 10 at room temperature (15-30°C) in a dry place, protected from light and moisture, and keep out of reach of children.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

scf -265, 2nd floor, motor market, manimajra, manimajra, chandigarh, haryana 160101

References

NHS UK. (n.d.). Diclofenac: medicine to relieve pain and swelling. NHS. Retrieved from https://www.nhs.uk/medicines/diclofenac/
U.S. National Library of Medicine. (2021, October 15). Acetaminophen: MedlinePlus Drug Information. MedlinePlus. Retrieved from https://medlineplus.gov/druginfo/meds/a681004.html
U.S. Food and Drug Administration. (2009). Clinical pharmacology and biopharmaceutics review(s). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2009/022165s000MedR.pdf
U.S. Food and Drug Administration. (2006). Labeling-Package Insert. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/040330s015,040341s013,040434s003lbl.pdf
Diclofenac: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a689002.html
PubChem. (n.d.-l). Diclofenac. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/diclofenac

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