Cofryl Syrup 100 Ml

Cof Ryl Syrup 100ml

Cipla Ltd.

Bottle of 100 ML

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MRP ~~₹99.82~~

₹49.81

₹1.00/ML

50.1% off

*MRP inclusive of all taxes

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Prescription required for this medicine

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Composition

Ammonium Chloride (138 Mg) + Diphenhydramine (14.08 Mg) + Sodium Citrate (57.03 Mg)

Cof-Ryl Syrup is a prescription cough medicine primarily used to manage coughs associated with respiratory tract conditions. This syrup is a combination medicine, and is part of the group of expectorants and antihistamines.

In addition to managing coughs, this syrup is also used to alleviate the symptoms of colds, allergies, inhaled irritants, bronchitis, and bronchial asthma. It assists in making your cough more productive by loosening mucus and phlegm, and provides relief from runny nose, sneezing, and itchy, watery eyes that accompany allergies and colds.

This medicine should be taken orally as directed by your doctor. Before you start taking this medicine, it’s crucial to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. To ensure optimal results, continue taking the syrup for the duration prescribed by your doctor.

Cof-Ryl Syrup is used for managing the following health conditions:

Relieving irritating, nonproductive cough associated with colds.
Alleviating cough symptoms in allergies.
Controlling cough due to inhaled irritants.
Managing cough related to bronchitis.
Treating bronchial asthma-induced cough.
Easing runny nose, sneezing and itchy, watery eyes linked with allergies and colds.

Directions for Use of Cof Ryl Syrup 100ml

To use Cof-Ryl Syrup correctly, please follow these steps:

Shake the bottle well before each use.
You can take this medicine with or without food.
This is a sugar-based medicine; if you have diabetes, consult your doctor before taking it.
Remember to store the bottle at room temperature, away from heat and direct light.
Once opened, use within a month.

Cof-Ryl Syrup is taken orally.

Cof-Ryl Syrup may have the following common side effects:

Drowsiness
Dizziness
Headache
Thickening of Bronchial Secretions: This refers to an increase in the thickness of mucus in the airways.
Stomach Upset
Nausea
Dry mouth, nose, and throat: This can make your mouth, nose, and throat feel very dry.
Constipation
Blurred Vision

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Cof-Ryl Syrup. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Thickening of bronchial secretions: Try drinking plenty of fluids to thin the mucus.
Stomach upset and nausea: Consider taking Cof-Ryl Syrup with food to lessen these effects.

Cof-Ryl Syrup contains three active ingredients:

Diphenhydramine (14.08 mg): This ingredient is an antihistamine that blocks the effects of histamine, thereby providing relief from symptoms like runny nose, sneezing, itching, and watery eyes. Additionally, it has a mild sedating effect that suppresses the cough reflex.
Ammonium chloride (138 mg): Acting as an expectorant, ammonium chloride helps to thin and loosen mucus in your airways, making it easier to cough up phlegm. It achieves this by increasing the pH of mucus, effectively liquefying it.
Sodium citrate (57.03 mg): Sodium citrate also possesses expectorant properties. It functions by increasing the volume and reducing the viscosity of respiratory tract secretions, which promotes the drainage of mucus.

Pregnancy

Caution is advised while taking Cof-Ryl Syrup if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Cof-Ryl Syrup should be used with caution while breastfeeding. Make sure you discuss this with your doctor before starting this medicine.

Alcohol

Alcohol interacts with Cof-Ryl Syrup and may increase drowsiness and dizziness. Hence, alcohol consumption should be avoided while taking this medicine.

Liver

If you have liver problems, it is advised to discuss them with your doctor before starting Cof-Ryl Syrup. This medicine may affect liver function.

Kidney

Caution is advised before using Cof-Ryl Syrup if you have a history of any kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

Cof-Ryl Syrup may cause drowsiness and dizziness. Avoid driving or operating machinery until you know how this medicine affects you.

Allergy

Cof-Ryl Syrup is contraindicated in patients with known hypersensitivity to any of the ingredients. If you have known allergies, consult your doctor before starting this medication.

Children

Cof-Ryl Syrup should be used with caution in children above 6 years of age, under medical supervision. It is not recommended for children under 6 years of age.

Older Patients

Older patients should take Cof-Ryl Syrup under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Cof-Ryl Syrup interacts with the following medicines:

Monoamine Oxidase Inhibitors (MAOIs): Medicines like phenelzine or isocarboxazid may interact with Cof-Ryl Syrup, potentially leading to a hypertensive crisis.
Central Nervous System Depressants: When taken with Cof-Ryl Syrup, sedatives and tranquilizers like diazepam and alprazolam can cause additive drowsiness and respiratory depression.
Anticholinergics: Medicines like atropine may interact with Cof-Ryl Syrup, leading to enhanced anticholinergic effects.
Antihypertensives: Concomitant use of medicines like amlodipine or lisinopril with Cof-Ryl Syrup may decrease their effectiveness.

Drug-Food Interactions

Drug-Disease Interactions

Cof-Ryl Syrup interacts with the following diseases:

Prostate enlargement or bladder neck obstruction: This medicine could exacerbate symptoms related to urinary retention.
Glaucoma: Patients with increased intraocular pressure should exercise caution while using this medicine as it could worsen their condition.
Asthma or Chronic Obstructive Pulmonary Disease (COPD): People suffering from breathing difficulties should use this medication carefully as it might lead to thickening of bronchial secretions.
Hypertension and heart diseases: Caution is recommended for individuals with high blood pressure or heart conditions as this medicine may cause fast or irregular heartbeat.
Hyperthyroidism: Those diagnosed with an overactive thyroid gland should consult their doctor before using this medicine as it might affect their medical condition.
Liver or Kidney Impairment: People with liver or kidney ailments should use this medicine cautiously, as it might influence their condition.

Daily Dose

Your doctor will prescribe the daily dose of Cof-Ryl Syrup based on your individual health condition and response to the medicine. It's crucial not to exceed this prescribed dosage without first consulting your doctor.

Over Dose

If you accidentally take more than your prescribed dose of Cof-Ryl Syrup, you may experience side effects such as drowsiness, dizziness, or an upset stomach. In such cases, it's advisable to inform your doctor.

Missed Dose

If you miss a dose of Cof-Ryl Syrup, take it as soon as you remember. But if it's nearly time for your next dose, skip the one you missed and continue with your regular schedule. Never double-up on doses without your doctor's advice.

Ensure to store Cof-Ryl Syrup at room temperature.
Keep it in a tightly closed container, safeguarded from light.
Make sure the syrup is kept out of reach of children.
Always use it before its expiry date.

Since Cof-Ryl Syrup is used to manage cough and respiratory issues, consider increasing your fluid intake. This can help thin down mucus, making it easier to cough up.
Avoid exposure to smoke and dust as these can irritate your airways and exacerbate symptoms.

Fact Box

Drug Category	Antihistamine, Expectorant
Therapeutic Category	Cough and Cold
Available Dosage Types	Syrup
Habit Forming	No
Ailment	Nonproductive Cough, Allergies

What is Cof-Ryl Syrup?

Cof-Ryl Syrup is a medicine that helps manage cough and symptoms associated with colds and allergies like a runny nose, sneezing, and itchy, watery eyes.

How does Cof-Ryl Syrup work?

The syrup contains three active ingredients, working together to block allergy-causing histamines, thin mucus in the airways, and suppress the cough reflex.

Can I take Cof-Ryl Syrup with food?

Yes, Cof-Ryl Syrup can be taken with or without food as it doesn't affect its efficacy.

What should I do if I experience side effects from Cof-Ryl Syrup?

Common side effects like drowsiness or stomach upset can be managed easily. However, if you experience serious side effects, consult your doctor immediately.

Can I take Cof-Ryl Syrup if I'm pregnant or breastfeeding?

Avoid taking Cof-Ryl Syrup if you're pregnant or breastfeeding unless your doctor advises that the benefits outweigh the risks.

Are there any specific precautions to consider while taking Cof-Ryl Syrup?

Yes, patients with certain conditions like glaucoma, asthma, heart disease, or liver impairment should use Cof-Ryl Syrup cautiously.

What happens if my cough persists even after taking Cof-Ryl Syrup?

If your cough lasts more than a week after starting the syrup or is accompanied by fever, rash or persistent headache, consult your doctor promptly.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

DIFENACOL. (2005). In Consumer Medicine Information. https://www.nps.org.au/assets/medicines/39a2e322-48df-42c7-9b08-a53300fece51.pdf
Ammonium chloride: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06767
Sodium citrate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09154
Diphenhydramine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01075

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