Febrinil Injection 21 Ml

Febrinil Injection 21ml

Maneesh Pharmaceuticals Ltd

Vial of 21 ML

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MRP ~~₹82.09~~

₹67.31

₹3.91/ML

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Composition

Benzyl Alcohol (2 %) + Paracetamol/acetaminophen (0.15 Gm)

Febrinil Injection is primarily used for the short-term management of moderate pain, especially following surgery. Additionally, it's an effective tool in managing fever when intravenous administration is considered necessary by your healthcare professional. This medicine is part of a group known as analgesics and antipyretics.

This injection is also used when oral administration isn't viable due to clinical conditions. It offers temporary relief from discomfort and helps lower body temperature in cases of fever, providing comfort during recovery.

Before you start administering this injection, it's important that you consult your doctor for proper dosage guidelines. Make sure to inform your doctor about any pre-existing conditions or ongoing medications to avoid potential complications. If you experience any side effects while using this medicine, inform your doctor promptly. For optimal results, continue using the medicine for the duration prescribed by your doctor.

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Febrinil Injection is used for the following:

Managing moderate pain, particularly after surgical procedures
Controlling fevers when oral administration isn't feasible.

Directions for Use of Febrinil Injection 21ml

Administer Febrinil Injection as follows:

This medicine is administered intravenously, that is, directly injected into your vein.
Make sure it's given as a 15-minute intravenous infusion.
Do not self-administer; it should be given by a medical professional or under their supervision.
Remember to consult your doctor for any specific instructions.

Febrinil Injection is administered intravenously.

Febrinil Injection might lead to the following common side effects:

Nausea
Vomiting
Headache
Insomnia: This refers to difficulty falling asleep or staying asleep.
Hypersensitivity reactions: This could be an allergic reaction, like rash or itching.
Local site reactions: You may experience pain, redness, swelling or burning at the injection site.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Febrinil Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are a couple of guidelines for managing common side effects:

Nausea: Administer Febrinil Injection with meals to help reduce these effects.
Insomnia: Consider having Febrinil Injection administered earlier in the day to lessen its impact on your sleep.

Febrinil Injection contains paracetamol (150 mg), which works on your body as follows:

Prostaglandin Synthesis Inhibition: Paracetamol primarily works by inhibiting the synthesis of prostaglandins in the central nervous system. Prostaglandins are substances in your body that cause feelings of pain and trigger fever.
Fever Reduction: The medicine also reduces fever by acting on the heat-regulating centres located in a part of your brain known as the hypothalamus. By doing so, it helps bring down your body temperature when you have a fever.
Pain Management: As an analgesic, paracetamol can help manage moderate pain effectively, especially post-surgical discomfort, by blocking pain signals to the brain.

Pregnancy

Febrinil Injection should only be used in pregnancy if the potential benefit justifies the possible risk to the foetus. Always consult your doctor before using this medicine.

Breastfeeding

Paracetamol is excreted in breast milk, but usually in low quantities that are unlikely to affect nursing infants. However, caution is advised while administering Febrinil Injection if you are breastfeeding.

Alcohol

Using alcohol while on Febrinil Injection can potentially harm your liver. It's recommended to limit or avoid alcohol consumption when taking this medicine.

Liver

Febrinil Injection is contraindicated for individuals with severe liver impairment or active liver disease. If you have a history of liver health problems, it is best to consult your doctor before using this medicine.

Kidney

Caution is advised when using Febrinil Injection if you have any kidney health concerns. Always consult your doctor before starting this medication.

Using Machines & Driving

If you feel unwell or experience side effects like dizziness, avoid these activities and consult your doctor.

Allergy

If you are allergic to paracetamol or any other ingredients in Febrinil Injection, do not use this medicine. If you experience symptoms like skin rash or breathing difficulties, seek immediate medical attention.

Children

Febrinil Injection can be administered safely to children aged 2 years and older for pain and fever management. However, always consult a doctor before giving this medicine to a child.

Older Patients

Older patients should administer Febrinil Injection under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Febrinil Injection interacts with the following medicines:

Hepatotoxic Medicines: When combined with Febrinil Injection, medications such as carbamazepine and isoniazid that are known to affect the liver may increase the risk of liver damage. It's important to monitor liver function if you're taking these medicines.
Anticoagulants: Medicines like warfarin, an anticoagulant, may have their effects increased when administered with Febrinil Injection. This could potentially increase the risk of bleeding.
Uricosuric Agents: Medications such as probenecid, which is used to treat gout and hyperuricemia, can increase and prolong the therapeutic effect of paracetamol, the active ingredient in Febrinil Injection.

Drug-Food Interactions

Febrinil Injection does not have any known interactions with food.

Drug-Disease Interactions

Febrinil Injection interacts with the following diseases:

Liver Disease: If you have severe hepatic impairment or active liver disease, use of Febrinil Injection is contraindicated, as it could exacerbate your condition.
Alcohol Dependence: As paracetamol, a component of Febrinil Injection, is metabolised by the liver, excessive alcohol consumption can increase the risk of liver damage. Therefore, caution is advised if you're a heavy drinker.

Daily Dose

The daily dose of Febrinil Injection should be administered as prescribed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In case of an accidental overdose, you might experience symptoms such as nausea, vomiting, or headache. If this happens, ensure you inform your doctor to get the right advice and medical care.

Missed Dose

If you forget to administer your regular dose of Febrinil Injection, do it as soon as you remember. However, if it's almost time for your next dose, skip the missed one now and resume your regular dosage schedule. Never increase your dosage without consulting your doctor.

Store your Febrinil Injection in a cool and dry place, ideally at a temperature below 30°C.
Keep the vials away from direct light and moisture.
Ensure it is kept out of reach and sight of children.

If you're managing pain, consider incorporating foods rich in omega-3 fatty acids like fish and nuts into your diet. These nutrients may help reduce inflammation, which can contribute to discomfort.
As Febrinil Injection is used to manage fever, staying well-hydrated is crucial. Include fluids like water, soup, and fruit juices in your regular intake to replace the fluids lost due to fever.

Fact Box

Drug Category	Prostaglandin Synthesis Inhibitor
Therapeutic Category	Analgesic and Antipyretic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Post-Surgery Pain, Fever

What is Febrinil Injection used for?

Febrinil Injection is used to manage moderate pain, particularly after surgery, and fever when oral administration isn't possible.

How does Febrinil Injection work?

It contains paracetamol, which reduces pain and fever by blocking the production of certain chemicals in the brain that trigger pain and heat.

Can I use Febrinil Injection if I have liver disease?

No, it's not advisable for those with severe liver disease or active liver issues as paracetamol is metabolised in the liver.

Are there any side effects of Febrinil Injection?

Yes, common side effects include nausea, vomiting, headache, insomnia, and reactions at the injection site like pain or redness.

What precautions should be taken while using Febrinil Injection?

Avoid exceeding the recommended daily dose as it may lead to liver damage. Also, stop its use immediately if a serious skin reaction occurs.

Can pregnant or nursing women use Febrinil Injection?

The safety of this medicine during pregnancy or lactation isn't well-studied. It should be used only when necessary, upon consulting a doctor.

What happens if someone overdoses on Febrinil Injection?

Overdosing can cause liver injury. In such cases, immediately seek emergency medical attention and contact poison control.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 5 years

MBBS

Check out Editorial Policy

Manufacturer details

29/33 , Ancillary Industrial Plots, Govandi Mumbai Mumbai City - 400043 Maharashtra - India

Country of origin: INDIA

References

Acetaminophen. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00316
Acetaminophen. (2022, June 9). U.S. Food and Drug Administration. https://www.fda.gov/drugs/information-drug-class/acetaminophen
Acetaminophen: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a681004.html
Acetaminophen - StatPearls - NCBI bookshelf. (2023, June 20). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK482369/
PubChem. (n.d.). Acetaminophen. https://pubchem.ncbi.nlm.nih.gov/compound/Acetaminophen

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