Fluzin 10 Mg Tablet 10

Fluzin 10 Tablet 10

Knoll Healthcare Pvt. Ltd.

Strip of 10 Units

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MRP ~~₹53.7~~

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₹5.37/Units

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Composition

Flunarizine (10 Mg)

Strength:

5 MG 10 MG

Fluzin-10 Tablet is primarily used to manage migraine headaches. This medicine belongs to a group of medications known as selective calcium channel blockers.

In addition to its main use, this tablet also aids in reducing the frequency, severity, and duration of migraine attacks. However, it's important to note that this medicine does not have immediate effects on an ongoing migraine attack.

Before you start taking this medicine, ensure you consult your doctor for the correct dosage and frequency according to your health condition. Inform your doctor if you have any pre-existing conditions or are on any other medications. If you notice any side effects while taking this medicine, immediately inform your doctor. It's crucial to continue taking the medicine for the entire duration prescribed by your doctor for optimal results.

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Prevention of migraine headaches: This medicine reduces the frequency, severity and duration of migraines in adults.
Management of vasospasm: Fluzin-10 Tablet helps relax blood vessels in the brain, thus managing vasospasms which can trigger migraines.

Directions for Use of Fluzin 10 Tablet 10

Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
Avoid crushing or chewing the tablet.
Do not take more than your doctor has advised.
It's essential not to stop taking this medicine without consulting your doctor first.

Fluzin-10 Tablet is taken orally.

Drowsiness, fatigue, lethargy
Weight gain, increased appetite
Mood changes
Extrapyramidal symptoms: You may experience involuntary movements, tremors or muscle stiffness, which are known as extrapyramidal symptoms.
Gastrointestinal disturbances: These include nausea, heartburn, and bloating.
Dry mouth
Dizziness
Headache

Managing the Side Effects:

Drowsiness: Consider taking Fluzin-10 Tablet at night if it causes you drowsiness during the day.
Gastrointestinal disturbances: If you experience nausea or bloating, take this medicine after meals to lessen this effect.

Fluzin-10 Tablet consists of flunarizine (10 mg), which works as follows:

Blocking Voltage-Gated Calcium Channels: Flunarizine works by blocking certain channels in your brain that allow calcium ions to pass through. These channels are located in cerebral blood vessels and neurons.
Relaxing Cerebral Blood Vessels: By blocking these calcium channels, Flunarizine relaxes the blood vessels in your brain, reducing vasospasm, which often contributes to migraines.
Preventing Abnormal Neuronal Activity: This process also prevents abnormal neuronal activity that can trigger migraines.
Antihistamine and Antiserotoninergic Properties: Furthermore, Flunarizine has properties that work against histamine and serotonin, which may contribute to its ability to prevent migraines.

Pregnancy

Fluzin-10 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Fluzin-10 Tablet is contraindicated for breastfeeding/lactating women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol when taking Fluzin-10 Tablet as it might increase drowsiness and impair your alertness.

Liver

Caution is advised while taking Fluzin-10 Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting Fluzin-10 Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Fluzin-10 Tablet if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Fluzin-10 Tablet can cause drowsiness which may affect your ability to drive or operate machinery. Please be cautious about engaging in such activities until you know how the medicine affects you.

Allergy

Do not take Fluzin-10 Tablet if you have known hypersensitivity to flunarizine or any other components of the tablet. If you suspect an allergic reaction after taking the tablet, seek medical help immediately.

Children

Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Fluzin-10 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Central Nervous System (CNS) depressants: When taken with medications such as diazepam or phenobarbitone, Fluzin-10 Tablet can increase their sedative effects.
Dopaminergic antiparkinsonian medications: Medications used for Parkinson's disease like levodopa might have their effects reduced when taken with Fluzin-10 Tablet.
CYP2D6 inhibitors: Certain medicines like quinidine, fluoxetine, or paroxetine can increase the levels of flunarizine in your body when taken together with Fluzin-10 Tablet.

Drug-Food Interactions

Consuming large quantities of grapefruit juice may increase the oral bioavailability of flunarizine in Fluzin-10 Tablet, potentially leading to increased side effects.

Drug-Disease Interactions

Depressive illness: Those with a history of depression should use caution as Fluzin-10 Tablet may exacerbate depressive symptoms.
Parkinson's disease: If you have pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders, taking Fluzin-10 Tablet may worsen these conditions.

Daily Dose

The daily dose of Fluzin-10 Tablet should be taken as prescribed by your doctor. The dosage may vary based on factors like the severity of your condition and how you respond to the medicine. It's crucial to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In case of an overdose, you may experience symptoms such as excessive drowsiness, confusion, or involuntary bodily movements. If you've taken too much Fluzin-10 Tablet and notice these symptoms, it's important to inform your doctor.

Missed Dose

If you forget to take Fluzin-10 Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double up on doses without consulting your doctor.

Store Fluzin-10 Tablet under 30°C, ideally in a cool, dry place.
Shield the medicine from direct sunlight and moisture to retain its efficacy.
Keep it safely out of reach and sight of children to prevent accidental ingestion.
Always check the expiry date on the pack before use; do not consume post-expiry.

Regular aerobic exercise can help decrease the frequency and severity of migraines. Aim for at least 150 minutes per week spread across most days.
Certain foods such as aged cheese, chocolate, and citrus fruits can trigger migraines in some individuals. Try maintaining a food diary to identify potential triggers and avoid them accordingly.

Fact Box

Drug Category	Calcium Channel Blocker
Therapeutic Category	Migraine Preventive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Migraine Prophylaxis

What is Fluzin-10 Tablet used for?

Fluzin-10 Tablet is used to prevent migraine headaches by reducing their frequency, severity and duration.

How does Fluzin-10 Tablet work?

The active ingredient in Fluzin, flunarizine, relaxes blood vessels in the brain, reducing abnormal activity that triggers migraines.

How long does it take for Fluzin-10 Tablet to start working?

Fluzin may take up to 6-8 weeks to show full effects in reducing migraine frequency and severity.

Can I stop taking Fluzin-10 Tablet abruptly?

No, abrupt discontinuation should be avoided. Consult your doctor for advice on gradually reducing the dose.

Can pregnant or breastfeeding women take Fluzin-10 Tablet?

No, Fluzin is contraindicated during pregnancy and lactation due to potential harm to the baby.

Are there any side effects of taking Fluzin-10 Tablet?

Common side effects include drowsiness, weight gain, mood changes and gastrointestinal disturbances among others.

Can I take other medicines while on Fluzin-10 Tablet?

Some medicines may interact with Fluzin. Always consult your doctor before starting any new medication.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Sibelium. (n.d.). PACKAGE LEAFLET: INFORMATION FOR THE USER - Sibelium 5 mg Tablets. https://www.hpra.ie/img/uploaded/swedocuments/bc725729-1dcc-48c0-b451-a3149ca2f886.pdf
AA PHARMA INC. (2010). PRODUCT MONOGRAPH FLUNARIZINE. https://www.aapharma.ca/downloads/en/PIL/2016/Flunarizine-PM.pdf
National Institute of Child Health and Human Development. (2022, November 30). Flunarizine. Drugs and Lactation Database (LactMed®) - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK525505/
PubChem. (n.d.). Flunarizine. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Flunarizine
Flunarizine: uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04841

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