Norflox Tz Rf Tablet 10

Cipla Ltd.

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Composition

Norfloxacin (400 Mg) + Tinidazole (600 Mg)

Norflox-TZ RF Tablet is an antibiotic combination used to treat various bacterial and parasitic infections. It contains Norfloxacin, a fluoroquinolone antibiotic, and Tinidazole, an antiparasitic. Norfloxacin works by preventing bacterial cell division, while Tinidazole kills parasites by damaging their DNA. This tablet is commonly prescribed for urinary tract infections, diarrhoea, dysentery, and severe stomach infections.

Norflox should not be used in patients who are allergic to fluoroquinolone antibiotics or in children under 18 years of age, as it may cause joint and tendon problems. It is also not recommended for use in pregnant or breastfeeding women unless absolutely necessary.

Norflox-TZ RF Tablet treats bacterial infections, including urinary tract infections (UTIs) and bacterial gastroenteritis causing loose motion.

Directions for Use of Norflox Tz Rf Tablet 10

Norflox-TZ RF tablet is an antibiotic medication commonly used to treat bacterial infections such as urinary tract infections, respiratory tract infections, gastrointestinal infections, and skin and soft tissue infections. It works by inhibiting bacterial DNA replication, ultimately leading to the bacteria's death.

Here are the general directions for using Norflox-TZ RF Tablet:

Norflox-TZ RF Tablet should be swallowed whole with a full glass of water and taken with food.
Do not crush, chew, or break the Norflox-TZ RF Tablet.
It would be best to take it at a fixed time for optimal results.
It would be best if you consumed what your doctor prescribes.

It is essential to follow these directions and consult your doctor and pharmacist for instructions regarding using Norflox-TZ RF Tablet for your particular condition.

Norflox-TZ RF Tablet is primarily available in tablet form and is meant to be taken orally.

Here are some potential Norflox-TZ RF side effects:

Nausea, vomiting, diarrhoea, stomach pain, and loss of appetite are common side effects of Norflox-TZ RF Tablet.
Headache, dizziness, and fatigue may also occur.
Rash or itching may occur in some people who take Norflox-TZ RF Tablet.
Norflox-TZ RF Tablet may also cause joint pain or swelling, particularly in elderly patients.

Managing the Side Effects:

Like all medications, Norflox may cause side effects in some people. Here are some tips on managing the side effects of Norflox-TZ RF Tablet:

Nausea and vomiting: If you experience nausea and vomiting while taking Norflox-TZ RF Tablet, try taking the medication with food. Avoid spicy or fatty foods and stick to bland, easy-to-digest foods like toast, crackers, and soup. If your symptoms persist or become severe, contact your healthcare provider.
Diarrhoea: Diarrhoea is a common side effect of Norflox-TZ RF Tablet. It is important to drink plenty of fluids to stay hydrated and avoid dehydration. Avoid anti-diarrheal medications unless prescribed by your healthcare provider, as they can make the condition worse.
Dizziness and headache: If you experience dizziness or headache while taking Norflox-TZ RF Tablet, avoid driving or operating heavy machinery. Resting and taking over-the-counter pain relievers may help relieve the symptoms.
Abdominal pain: Abdominal pain is a common side effect of Norflox-TZ RF Tablet. Resting and applying heat compress on the affected area may help to relieve the pain. Over-the-counter pain relievers may also help relieve the symptoms.
Allergic reactions: Allergic reactions to Norflox-TZ RF Tablet are rare but can be serious. Seek emergency medical attention if you experience symptoms such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.

Norflox-TZ RF Tablet is an antibiotic medication that works by interfering with the DNA replication process of bacteria, ultimately leading to their death. The active ingredient in Norflox-TZ RF Tablet, Norfloxacin, is a fluoroquinolone antibiotic effective against many bacterial infections. Tinidazole is an antiprotozoal / antibiotic medication.

Norfloxacin inhibits the activity of two enzymes, DNA gyrase and topoisomerase IV, essential for bacterial DNA replication. By inhibiting these enzymes, Norflox-TZ RF Tablet prevents the bacteria from multiplying and spreading. This ultimately helps control bacterial infection and relieves fever, pain, and inflammation symptoms. Tinidazole, on the other hand, interferes with the DNA synthesis of bacteria and protozoa, leading to their death.

Norflox-TZ RF Tablet is particularly effective against Gram-negative bacteria such as E. coli, Salmonella, and Shigella, commonly associated with gastrointestinal infections. It is also effective against some Gram-positive bacteria, such as Staphylococcus aureus.

Pregnancy

Norflox-TZ RF Tablet in pregnancy should be avoided unless it is absolutely necessary, especially during the first trimester.

Breastfeeding

Norfloxacin passes into breast milk and may harm the nursing baby. Therefore, using Norflox-TZ RF Tablet while breastfeeding is generally not recommended. However, if it is necessary to use the tablet, it is advised to stop breastfeeding during the course of treatment. Consult your doctor before taking the Norflox-TZ RF Tablet.

Alcohol

It is not recommended to consume alcohol while taking the Norflox-TZ RF Tablet. Alcohol can increase the risk of side effects such as dizziness, confusion, and nausea.

Liver

Norflox-TZ RF Tablet is primarily metabolized in the liver, so it is important to be cautious while using this medication. If you have liver disease, it is essential to consult a doctor before using the tablet.

Kidney

Norflox-TZ RF Tablet is excreted through the kidneys, so it is important to monitor kidney function while taking this medication. If you have kidney disease, your doctor may need to adjust your dosage or avoid using Norflox-TZ RF Tablet altogether.

Using Machines & Driving

Norflox-TZ RF Tablet may cause dizziness or confusion, so it is essential to avoid driving or operating heavy machinery until you know how the medication affects you.

Allergy

If you are allergic to Norflox-TZ RF Tablet or any other fluoroquinolone antibiotics, you should not take this medication as it can cause serious allergic reactions. Signs of an allergic reaction may include rash, itching, swelling, dizziness, or difficulty breathing. If you experience any of these symptoms, seek medical attention immediately.

Children

Norflox-TZ RF Tablet is generally not recommended for children under 18 years of age due to the potential risk of adverse effects on bone and joint development.

Older Patients

Older patients may be more susceptible to the side effects of Norflox-TZ RF Tablet, particularly tendon problems. It is important to monitor older patients closely while they are taking the tablet.

Drug-Drug Interactions

Norflox-TZ RF Tablet may interact with other medications that you are taking, including.

Antacids
Iron supplements
Probenecid
Certain anticoagulants such as Warfarin.
Theophylline
NSAIDs

You must inform your doctor about all the medications you are taking before starting the Norflox-TZ RF Tablet. Your doctor may need to adjust your dosage or avoid using certain medications while you are taking the tablet.

Drug-Food Interactions

Norflox-TZ RF Tablet should be taken on an empty stomach at least 1 hour before or 2 hours after a meal. This is because food can decrease the absorption of Norflox-TZ RF Tablet into the bloodstream. Foods that can interact with Norflox-TZ RF Tablet are:

Dairy products: Calcium-containing foods like milk, cheese, and yogurt
Caffeine

Drug-Disease Interactions

Norflox-TZ RF Tablet may be contraindicated or require special precautions in patients with certain medical conditions, such as:

Central nervous system disorders
Renal impairment
QT prolongation

Daily Dose

The recommended daily dose of Norflox-TZ RF Tablet is once a day, with food, as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

An overdose of Norflox-TZ RF Tablet can cause serious side effects such as seizures, hallucinations, confusion, and arrhythmias. If you suspect an overdose, seek medical attention immediately. It is essential to avoid taking more than the prescribed dose of Norflox-TZ RF tablet.

Missed Dose

If you miss a dose of Norflox-TZ RF Tablet, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose. If you are unsure about what to do, consult your healthcare provider.

You must follow the dosage instructions provided by the doctor and take Norflox-TZ RF Tablet as directed for the entire duration of treatment. Do not adjust your dosage or stop taking Norflox-TZ RF Tablet without consulting your doctor.

Here are some essential points to keep in mind regarding the storage of Norflox-TZ RF Tablet:

Store Norflox-TZ RF Tablet at room temperature (between 20-25°C).
Protect the tablets from moisture and direct sunlight.
Keep Norflox-TZ RF Tablet out of the reach of children and pets.

In addition to taking medication as prescribed by your doctor, some diet and lifestyle considerations can help improve the effectiveness of Norflox-TZ RF Tablet and reduce the risk of side effects. Here are some general guidelines to follow while taking Norflox-TZ RF Tablet:

Drink plenty of fluids as it is vital to stay hydrated while taking Norflox-TZ RF Tablet to help flush the medication out of your system and reduce the risk of side effects. Aim for 8-10 glasses of water at least per day.
Avoid alcohol as it can interfere with the effectiveness of Norflox-TZ RF Tablet and increase the risk of side effects. It is recommended to avoid alcohol while taking this medication.
Follow a healthy diet. Eating a well-balanced diet can help boost your immune system and support your overall health while taking Norflox-TZ RF Tablet.
Avoid high-fat meals with Norflox-TZ RF Tablet. As it should be taken on an empty stomach or along a light meal to help improve absorption.
Regular exercise can help improve overall health and boost the immune system. However, it is important to avoid strenuous exercise while taking Norflox-TZ RF Tablet to reduce the risk of tendon damage.
Always take Norflox-TZ RF Tablet as prescribed, and do not change the dosage or frequency of administration without consulting the doctor.

Some quick tips that you can keep in mind when taking Norflox-TZ RF Tablet include:

Norflox-TZ RF Tablet should be taken on an empty stomach or with a light meal, as high-fat meals can decrease effectiveness.
Drink plenty of fluids while taking Norflox-TZ RF Tablet to stay hydrated.
Avoid alcohol while taking Norflox-TZ RF Tablet, as it can interfere with the effectiveness of the medication and increase the risk of side effects.
Do not take antacids or mineral supplements within two hours before or after taking Norflox-TZ RF Tablet, as they can decrease its absorption.

Fact Box

Drug Category	Fluoroquinolone, Nitroimidazole
Therapeutic Category	Antibiotic
Available Dosage Types	Tablet, Oral Suspension, Eye Drops, Injection
Habit Forming	No
Ailment	Bacterial infections, UTI, Gastrointestinal infections

Is Norflox-TZ RF Tablet good for urine infection?

Yes, Norflox-TZ RF Tablet is used for treating urinary tract infections (UTIs) caused by susceptible bacteria. It works by preventing the growth and multiplication of bacteria in the urinary tract, thus helping to relieve the symptoms of the infection.

How many times should the Norflox-TZ RF Tablet be taken?

The dosage and duration of treatment with Norflox-TZ RF Tablet may vary depending on the severity of the infection and other individual factors. However, taking one Norflox-TZ RF tablet daily or as directed by a doctor is usually recommended.

Can Norflox-TZ RF Tablet be taken on an empty stomach?

Norflox-TZ RF Tablet can be taken with food. However, taking it with a full glass of water is recommended to avoid stomach upset, preferably after a meal.

Is Norfloxacin a strong antibiotic?

Norfloxacin is a broad-spectrum antibiotic that belongs to the class of fluoroquinolones. It is effective against many bacteria, including gram-negative and gram-positive bacteria. However, the strength of the antibiotic may depend on the specific infection being treated and other individual factors.

Can I take the Norflox-TZ RF Tablet twice a day?

It is recommended to take Norflox-TZ RF Tablet as prescribed by a healthcare provider. Typically, the dosage and frequency of taking the medication are determined by the severity of the infection and other individual factors. Therefore, it is important to consult with a doctor before making any changes to the dosage or frequency of taking Norflox-TZ RF Tablet.

What is the Norflox-TZ RF tablet used for?

Norflox-TZ RF Tablet combines Norfloxacin and Tinidazole to treat bacterial infections like UTIs and diarrhea. Norfloxacin prevents bacterial DNA replication, while Tinidazole targets and kills parasites and bacteria, making it effective against both bacterial and protozoal infections.

Can Norflox-TZ RF Tablet increase the risk of tendon rupture?

Yes, the use of the Norflox-TZ RF tablet may increase the risk of tendon rupture, particularly in elderly patients and in those who have a history of tendon disorders. Therefore, it is recommended to use the Norflox-TZ RF tablet cautiously and only as directed by the physician.

Last Updated On 18 Nov. 2024 | 2:02PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

Norfloxacin and Tinidazole Tablets. MedlinePlus. [Updated on 15th April 2022] [Accessed on 4th May 2023] https://medlineplus.gov/druginfo/meds/a601117.html
Norfloxacin and Tinidazole Tablets. National Health Service (NHS). [Updated on 26th January 2022] [Accessed on 4th May 2023] https://www.nhs.uk/medicines/norfloxacin-and-tinidazole-tablets/
Norfloxacin and Tinidazole Tablets. Drugs.com. [Updated on 14th April 2022] [Accessed on 4th May 2023] https://www.drugs.com/uk/norfloxacin-and-tinidazole-400-mg-600-mg-tablets-leaflet.html
Norfloxacin and Tinidazole Tablets. European Medicines Agency (EMA). [Updated on 23rd February 2021] [Accessed on 4th May 2023] https://www.ema.europa.eu/en/medicines/human/referrals/norfloxacin-tinidazole
Norfloxacin and Tinidazole Tablets. Mylan. [Accessed on 4th May 2023] https://www.mylan.com/en/products/product-catalog/norfloxacin-and-tinidazole-tablets

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