Pentanerv 300 Tablet 10

Alkem Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹278.00~~

₹230.74

₹27.80/Units

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Composition

Gabapentin (300 Mg)

Pentanerv 300 Tablet 10 is primarily used to manage neuropathic pain and certain types of seizures. As a member of the anticonvulsant class of medicines, it works effectively to control conditions linked with abnormal electrical activity in the brain.

In addition to these primary uses, this medicine is also beneficial for reducing neuropathic pain that typically follows a bout of shingles.

Before starting this medicine, it's important to consult your doctor for the correct dosage and frequency. Be sure to inform your doctor about any existing health conditions or ongoing medications you're taking. While on this medicine, keep an eye out for any side effects and report them to your doctor promptly. Continue taking the medicine for the duration prescribed by your doctor to ensure optimal results.

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Pentanerv 300 Tablet 10 is used for the following:

Managing postherpetic neuralgia, which is nerve pain caused by shingles
As an additional medication for controlling partial seizures in adults and children over 6 years of age

Directions for Use of Pentanerv 300 Tablet 10

Swallow the tablet whole with a glass of water.
Do not chew or crush the tablet.
Avoid exceeding the recommended dose without your doctor's guidance.
It's important not to stop taking this medicine without consulting your doctor first.

Pentanerv 300 Tablet 10 is taken orally.

Taking Pentanerv 300 Tablet 10 may result in some common side effects. These include:

Dizziness
Fatigue
Nausea
Vomiting

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Pentanerv 300 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here's how you can manage some common side effects:

Dizziness: If this medicine makes you feel dizzy, consider taking it before bedtime.
Nausea and Vomiting: Try taking Pentanerv 300 Tablet 10 with food or after meals to lessen this effect.

Pentanerv 300 Tablet 10 contains gabapentin (300 mg). Here's how it acts within your body:

Prevention of Allodynia and Hyperalgesia: Gabapentin works by suppressing these two conditions, which are associated with neuropathic pain. Allodynia involves a heightened sensitivity where even mild touch can cause pain, while hyperalgesia is an increased response to painful stimuli.
Anticonvulsant Activity: This medication also prevents seizures by controlling the abnormal electrical activity in your brain, which often leads to seizures.

Pregnancy

Caution is advised while taking Pentanerv 300 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Pentanerv 300 Tablet 10 is secreted into human milk. Therefore, it's recommended to consult your doctor if you are breastfeeding, as the benefits need to outweigh the risks.

Alcohol

Both alcohol and gabapentin can cause drowsiness and fatigue, and when taken together, these effects may be amplified. It is not recommended to take alcohol consumption while taking gabapentin use to gauge its effects.

Liver

Pentanerv 300 Tablet 10 doesn't have any known significant interactions with liver health. However, if you have liver health issues, consultation with your doctor is advised before starting this medicine.

Kidney

If you have kidney health issues, be careful while taking Pentanerv 300 Tablet 10. This medicine may pose a risk due to its elimination through the kidneys. Always consult your doctor in such cases.

Using Machines & Driving

As Pentanerv 300 Tablet 10 may cause dizziness and somnolence, it's important not to drive or operate heavy machinery until you know how the medicine affects you.

Allergy

If you know you're allergic to gabapentin or any other ingredient in Pentanerv 300 Tablet 10, avoid taking this medicine. In case of an allergic reaction, seek immediate medical help.

Children

For children aged 6 years and above, Pentanerv 300 Tablet 10 can be used as prescribed by the doctor. It's not suitable for children below this age.

Older Patients

Older patients may be more susceptible to the side effects of Pentanerv 300 Tablet 10. If patients are above 70 years of age or have liver and kidney issues, caution is advised, and they should use this medication under medical supervision.

Drug-Drug Interactions

Pentanerv 300 Tablet 10 interacts with the following medicines:

Sedatives: If you're taking medicines such as diazepam or lorazepam, which have calming effects, combining them with Pentanerv 300 Tablet 10 could result in increased drowsiness and sedative effects.
Kidney function affecting medicines: Medicines such as furosemide or hydrochlorothiazide that affect kidney function may increase gabapentin levels in the blood due to reduced renal clearance.

Drug-Food Interactions

There are no known specific food interactions with Pentanerv 300 Tablet 10.

Drug-Disease Interactions

Pentanerv 300 Tablet 10 interacts with the following diseases:

Renal Impairment: If you have kidney disease, gabapentin levels might be elevated in your body due to reduced renal clearance. This could lead to an increased risk of adverse reactions.
Central Nervous System (CNS) Depression: In conditions causing CNS depression, such as brain injury or certain brain diseases, adding Pentanerv 300 Tablet 10 could potentially exaggerate the depressive effects on the brain.

Daily Dose

The recommended dose of Pentanerv 300 Tablet 10 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor. For further details regarding dosage, read the package insert.

Over Dose

If you accidentally take more Pentanerv 300 Tablet 10 than prescribed, you might experience symptoms like dizziness, double vision, or drowsiness. In such cases, you should inform your doctor.

Missed Dose

If you forget to take your regular dose of Pentanerv 300 Tablet 10, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular dosage schedule. Never adjust your dosage without consulting your doctor.

Store Pentanerv 300 Tablet 10 at room temperature, ideally between 20°C to 25°C.
Keep the medicine away from direct light and moisture.
Ensure the packaging is securely closed after use.
Always keep this medicine out of reach from children.
Make sure you use the medicine before its expiry date.

If you or your child are taking Pentanerv 300 Tablet 10 for managing epilepsy, try to maintain regular sleep patterns. Disturbed sleep can potentially trigger seizures.
For those using this medicine to manage neuropathic pain, such as postherpetic neuralgia, gentle exercises like walking can help in reducing pain levels. However, consult your doctor for specific exercise recommendations.

Fact Box

Drug Category	Analgesic, Anticonvulsant
Therapeutic Category	Neuropathic Pain Reliever
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Postherpetic Neuralgia, Partial Seizures

What is Pentanerv 300 Tablet 10 used for?

This medicine is used to manage neuropathic pain, like the pain following shingles, and to help control certain types of seizures in adults and children over 6 years old.

How does Pentanerv 300 Tablet 10 work?

Pentanerv 300 Tablet 10 contains gabapentin, which helps reduce pain by altering the way your body senses pain. It also works by preventing seizures by reducing abnormal electrical activity in the brain.

Can I drive or operate machinery after taking this medicine?

You should avoid driving or operating machinery until you know how Pentanerv 300 Tablet 10 affects you, as it may cause drowsiness and affect your ability to concentrate.

Can I take Pentanerv 300 Tablet 10 if I have kidney problems?

If you have kidney problems, please consult your doctor before taking Pentanerv 300 Tablet 10, as it may increase the risk of side effects due to its removal through the kidneys.

Are there any side effects of taking Pentanerv 300 Tablet 10?

Yes, common side effects include dizziness, sleepiness, nausea, vomiting, and fatigue. Consult your doctor if they persist or worsen.

Is it safe to take Pentanerv 300 Tablet 10 during pregnancy or breastfeeding?

Please consult your doctor before taking this medicine during pregnancy or breastfeeding, as its effects on the baby are not fully known.

What should I do in case of an overdose of Pentanerv 300 Tablet 10?

In case of an overdose, seek immediate medical help. Symptoms may include dizziness, blurred vision, slurred speech, and drowsiness.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

References

GABAPENTIN- gabapentin capsule. (n.d.). DailyMed. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0936a88f-b569-49c4-951b-14e8f6273b53
Gabapentin and Prodrugs. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/categories/DBCAT003963
Gabapentin: MedlinePlus drug information. (n.d.). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a694007.html
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3446, Gabapentin. Retrieved June 20, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Gabapentin.
Myrick, H., Anton, R., Voronin, K., Wang, W., & Henderson, S. (2007). A double-blind evaluation of gabapentin on alcohol effects and drinking in a clinical laboratory paradigm. Alcoholism, clinical and experimental research, 31(2), 221–227. https://doi.org/10.1111/j.1530-0277.2006.00299.x

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