Pregalup Syrup 200 Ml

Pegalup Solution 200ml

Lupin Ltd

BOTTLE of 100 ML
BOTTLE of 200 ML

MRP ~~₹427.45~~

₹350.51

₹2.14/ML

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Composition

Polyethylene Glycol (13.125 Gm) + Potassium Chloride (0.0466 Gm) + Sodium Bicarbonate (0.1785 Gm) + Sodium Chloride (0.3507 Gm)

Pegalup Oral Solution is primarily used to cleanse the bowel before colonoscopy or other intestinal procedures. It belongs to the category of osmotic laxatives, a group of medicines that help to clear the bowel by increasing the water content in the stool.

In addition to preparation for colonoscopy, this Oral Solution is also beneficial for other diagnostic procedures like barium enema X-rays where a clean intestinal tract is required for optimal visualisation. It is, thereby, an effective solution for ensuring a thoroughly clean bowel.

It's important to consult your doctor about the appropriate dosage and frequency of this medicine based on your health condition. Before starting this oral solution, be sure to keep your doctor informed about any ongoing medications or pre-existing diseases. If you experience any side effects, do not hesitate to notify your doctor right away. For best results, continue using this as prescribed by your doctor.

Pegalup Oral Solution is used for the following health conditions:

Preparing the colon for colonoscopy procedures
Cleaning the bowel before other intestinal procedures
Maintaining fluid and electrolyte balance during bowel cleansing.

Directions for Use of Pegalup Solution 200ml

Follow these instructions while taking Pegalup Oral Solution:

Use a measuring cup to measure the correct dose of the Oral Solution.
This medicine is sugar-based and needs caution for use in diabetic patients. If you have diabetes, consult your doctor before taking this medicine.
Keep the bottle well-capped after use.
Remember to consume additional clear liquids before, during and after taking this medicine to maintain hydration.

Pegalup Oral Solution is taken orally.

Pegalup Oral Solution may have the following common side effects:

Nausea.
Abdominal fullness
Bloating: This can cause your stomach to feel swollen, tight or hard.
Abdominal cramps
Vomiting
Anal irritation

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pegalup Oral Solution. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Pegalup Oral Solution with food to alleviate this effect.
Abdominal cramps: Consider taking this medicine at night if it causes you discomfort during the day.

Pegalup Oral Solution contains four active ingredients each having its unique role:

Polyethylene Glycol (13.125 GM): This non-absorbable, osmotically active compound stays within the colon and increases the water content in the stool, thereby softening it and aiding in bowel movement.
Sodium Chloride (0.3507 GM): Being osmotically active, sodium chloride helps maintain the electrolyte balance in your body and manages fluid distribution and osmotic pressure.
Sodium Bicarbonate (0.1785 GM): Similar to sodium chloride, sodium bicarbonate also contributes to maintaining electrolyte balance.
Potassium Chloride (0.0466 GM): This ingredient prevents a condition called hypokalemia, which can occur due to loss of potassium in stools as a result of the laxative action.

Pregnancy

If you're pregnant, proceed with caution while taking Pegalup Oral Solution. It's best to consult your doctor before starting this medicine.

Breastfeeding

While lactating, breastfeeding isn't recommended during the usage of Pegalup Oral Solution and for 24 hours after the last dose. Please discuss this with your doctor.

Alcohol

The interaction between Pegalup Oral Solution and alcohol is unknown. To be safe, it's advisable to consult your doctor before consume.

Liver

Pegalup Oral Solution should be used with caution if you have liver issues, especially if you have advanced liver disease. Ensure that you consult your doctor before starting on this medicine.

Kidney

If you've had kidney problems in the past, use Pegalup Oral Solution with caution. It might be necessary to adjust the dosage or monitor your condition more closely.

Using Machines & Driving

There's no known impact of Pegalup Oral Solution on the ability to operate machinery or drive. However, if you feel unwell after taking the medicine, do not drive or operate machinery till you feel better.

Allergy

If you're allergic to any of the components of Pegalup Oral Solution, avoid using it. Make sure to share your allergy history with your doctor before starting this medicine.

Children

Pegalup Oral Solution is safe for use in children aged 6 months and older but must be administered under medical supervision.

Older Patients

Older patients should use Pegalup Oral Solution with care as they may have a higher risk of fluid-electrolyte imbalance and renal dysfunction. Your doctor will guide you based on your health condition.

Drug-Drug Interactions

Pegalup Oral Solution interact with the following medicines:

Diuretics: Medicines such as furosemide and hydrochlorothiazide may interact with Pegalup Oral Solution, potentially increasing the risk of fluid and electrolyte imbalance.
ACE Inhibitors: Medicines like enalapril or lisinopril when taken with Pegalup Oral Solution might elevate potassium levels in your blood, which can lead to hyperkalemia.
NSAIDs: Non-Steroidal Anti-Inflammatory medicine like ibuprofen and naproxen, when used concurrently with Pegalup Oral Solution, can accentuate the risk of fluid and electrolyte imbalance.
Stimulant Laxatives: Using stimulant laxatives like bisacodyl or senna together with Pegalup Oral Solution can increase the risk of mucosal ulcerations and ischemic colitis.

Drug-Food Interactions

There are no specific known food interactions with Pegalup Oral Solution. However, during its use, it is crucial to maintain a proper intake of clear fluids for optimal hydration.

Drug-Disease Interactions

Pegalup Oral Solution interacts with the following diseases:

Congestive Heart Failure: Patients suffering from this condition should be cautious while using Pegalup Oral Solution as it may exacerbate fluid and electrolyte imbalances.
Advanced Liver Disease: As Pegalup Oral Solution could potentially worsen fluid and electrolyte disturbances, individuals with advanced liver diseases need to be careful while using this medicine.
Renal Impairment: Patients with kidney problems should be cautious since Pegalup Oral Solution can intensify fluid imbalances and might need dosage adjustment or increased monitoring.

Daily Dose

The daily dose of Pegalup Oral Solution should be taken as recommended by your doctor. Your dosage might be adjusted depending on factors such as the severity of your condition and how you respond to the medication. It's vital to stick to the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you take more Pegalup Oral Solution than instructed, you may experience intensified diarrhoea and increased fluid loss. It's important to manage these symptoms suitably and keep an eye on your fluid-electrolyte balance. In severe cases with impaired kidney function, dialysis might be needed.

Missed Dose

If you forget to take a dose of Pegalup Oral Solution, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose without checking with your doctor first.

Store Pegalup Oral Solution in a cool, dry place, ideally at a temperature not exceeding 30°C.
Keep it away from direct sunlight and excessive moisture.
Ensure it is out of reach of children at all times

As Pegalup Oral Solution is used for bowel cleansing, incorporate a high-fibre diet into your meals. This includes fruits, vegetables, whole grains and lentils which can help maintain regular bowel movements.
Stay well-hydrated. Drinking plenty of water not only aids in digestion but also helps prevent dehydration caused by diarrhoea that may occur after taking Pegalup Oral Solution.

Fact Box

Drug Category	Osmotic Laxative
Therapeutic Category	Bowel Cleanse
Available Dosage Types	Oral Solution
Habit Forming	No
Ailment	Colonoscopy Preparation, Bowel Cleanse for Diagnostic Procedures

What is Pegalup Oral Solution used for?

It's used to cleanse your colon before a colonoscopy or other intestinal procedures.

How does Pegalup Oral Solution work?

This medicine works by increasing the water content in your stool, promoting bowel movements and maintaining fluid and electrolyte balance.

Are there any potential side effects with Pegalup Oral Solution?

You might experience nausea, abdominal fullness, bloating, abdominal cramps, vomiting or anal irritation. Contact your doctor if these persist.

Can I take other medicines while using Pegalup Oral Solution?

Be cautious, as it may alter the absorption of oral medicines taken within 1 hour of starting the regimen.

Is Pegalup Oral Solution safe during pregnancy and breastfeeding?

The data on use during pregnancy is inadequate. Breastfeeding is not recommended during use and for 24 hours after the last dose.

What precautions should I take while using Pegalup Oral Solution?

Use it with caution if you have an impaired gag reflex, reflux, unconsciousness, altered mental status or certain health conditions.

What should I do in case of an overdose of Pegalup Oral Solution?

Overdose may intensify diarrhoea and fluid loss. Seek medical help immediately and ensure adequate hydration.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

References

Polyethylene glycol 3350: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a603032.html
Potassium chloride: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00761
Sodium bicarbonate: (n.d.). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8427947/
Sodium chloride: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09153

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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