Rocaltrol Capsule 10

Name: Rocaltrol Capsule 10
Brand: ROCALTROL
SKU: TM-CACR1-005332
Price: 280.09 INR
Availability: InStock

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Composition

Calcitriol/ Cholecalciferol (0.25 Mcg)

Rocaltrol Capsule is primarily used to manage low blood calcium levels, a condition known as hypocalcemia. This medication falls under the class of vitamin D analogues.

Besides managing hypocalcemia, this capsule plays a vital role in addressing bone disorders. These disorders often arise from chronic kidney disease or conditions like hypoparathyroidism and postmenopausal osteoporosis. The capsule is also used as adjunctive therapy to prevent osteoporosis induced by corticosteroids.

Before you start taking this capsule, it's important to consult your doctor who will guide you on the correct dosage and frequency. You should inform your doctor about any pre-existing conditions or ongoing medicines before starting this medicine. If you notice any side effects, promptly notify your doctor and continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Rocaltrol Capsule is used for the following:

Regulating low blood calcium levels, also known as hypocalcaemia
Management of bone disorders in chronic kidney disease patients undergoing dialysis
Handling lower calcium levels and associated bone diseases in individuals with hypoparathyroidism
Management and prevention of bone weakening in women after menopause, a condition known as postmenopausal osteoporosis
Supplementing regular treatment for prevention of bone thinning caused by long-term use of corticosteroids, known as corticosteroid-induced osteoporosis

Directions for Use of Rocaltrol Capsule 10

Here are some instructions to follow when taking Rocaltrol Capsule:

Rocaltrol Capsule is to be taken orally.
Swallow the capsule whole with a glass of water. Avoid breaking or chewing it.
You can take this medicine with or without food.
Always take the medicine as advised by your doctor. Do not self-adjust the dose or duration of treatment.
Remember not to discontinue taking this medicine without consulting your doctor first.

Rocaltrol Capsule is taken orally.

Taking Rocaltrol Capsule may result in some side effects. These can include:

Hypercalcaemia: This is an excess of calcium in your blood which can cause you to feel tired or weak.
Hypercalciuria: This is when there is too much calcium in your urine, which could potentially lead to kidney stones.
Nausea
Vomiting
Constipation
Abdominal pain
Pruritus: This is another name for intense itching of the skin.
Rash
Headache
Drowsiness
Confusion
Bone pain
Muscle weakness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Rocaltrol Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage some common side effects:

Nausea/Vomiting: Try taking Rocaltrol Capsule with food to reduce these feelings.
Constipation: Consider taking the capsule with plenty of water and maintain a diet high in fibre.

Rocaltrol Capsule contains calcitriol (0.25 mcg) which acts in the following ways:

Binding to Vitamin D Receptor: Calcitriol binds to the vitamin D receptor (VDR) present in target tissues like the intestine, bones, and parathyroid glands. This interaction helps regulate calcium absorption in the body.
Stimulates Bone Mineralisation: By acting on bones, calcitriol aids in bone mineralization or hardening of bones by depositing minerals such as calcium and phosphate onto the bone matrix.
Reduces Parathyroid Hormone Production: Calcitriol also affects your parathyroid glands, reducing the synthesis and secretion of parathyroid hormone (PTH). This hormone plays a key role in regulating calcium levels in your body.

This combined action helps maintain normal calcium and phosphate levels in the blood and promotes healthy bone formation.

Pregnancy

If you are pregnant, exercise caution whilst taking Rocaltrol Capsule. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding mothers should use Rocaltrol Capsule carefully. Always discuss your specific circumstances with your doctor before starting this medication.

Alcohol

Combining Rocaltrol Capsule with alcohol can impair calcium absorption and metabolism. It's best to limit or avoid alcohol to maintain the effectiveness of this medicine and support bone health.

Liver

If you have a history of liver problems, exercise caution when starting Rocaltrol Capsule. Discussing your liver health with your doctor prior to commencing this medicine is recommended.

Kidney

For those with a history of kidney issues, it's essential to be cautious when taking Rocaltrol Capsule. Consultation with a doctor before starting this medication is strongly suggested.

Using Machines & Driving

Rocaltrol Capsule may cause drowsiness or confusion in some individuals. If you experience these symptoms, avoid driving vehicles or operating heavy machinery.

Allergy

If you are allergic to calcitriol or any other ingredients of Rocaltrol Capsule, avoid using this medicine. Always inform your doctor about your allergies before starting any new medication.

Children

This medicine isn't generally recommended for children under 18 years of age. Always consult with a doctor before giving any medication to a child.

Older Patients

Older patients should use Rocaltrol Capsule under medical supervision as they may be more susceptible to its side effects, and may have underlying liver or kidney issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Thiazide Diuretics: Medicines like hydrochlorothiazide or bendroflumethiazide, when taken with Rocaltrol Capsule, may increase the risk of high calcium levels (hypercalcemia) in your blood.
Cardiac Glycosides: Medicines like digoxin or digitoxin may interact with Rocaltrol Capsule, ramping up the risk of irregular heart rhythms (cardiac arrhythmias).
Cholesterol Lowering Agents: Medications such as cholestyramine and colestipol can lower the absorption of calcitriol, the main ingredient in Rocaltrol Capsule.

Drug-Food Interactions

Consuming large amounts of dairy products or fish liver oils while taking this medication could increase your risk of hypercalcaemia.

Drug-Disease Interactions

Hypercalcaemia: Patients with high levels of calcium in their blood should be careful as Rocaltrol Capsule increases calcium absorption, potentially exacerbating their condition.
Malabsorption Syndrome: Those with this condition have trouble absorbing nutrients from food; they may not absorb enough calcitriol from Rocaltrol Capsule for it to work effectively.
Kidney Stones: People who've had kidney stones should use caution when taking this medicine as it could increase calcium levels in urine, causing stones to form again.

Daily Dose

The daily dose of Rocaltrol Capsule should be as prescribed by your doctor. The dosage may vary based on factors like the condition's severity and your response to treatment. It's crucial to follow your doctor's prescribed dosage and avoid exceeding it without consulting them.

Over Dose

If you accidentally take more Rocaltrol Capsules than prescribed, you may experience symptoms such as nausea, constipation, weakness, or confusion. If these symptoms persist or worsen, inform your doctor.

Missed Dose

If you forget to take your regular dose of Rocaltrol Capsule as instructed, try to take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.

Store your Rocaltrol Capsule at room temperature, ideally between 20°C to 25°C.
Keep them shielded from light and moisture to maintain their effectiveness.
Place the capsules in a safe spot, out of the reach of children.
Always check the expiry date on the pack before use.

Ensure sufficient intake of calcium and phosphate through diet or supplements, as these minerals are essential for maintaining healthy bones and teeth, a key aspect managed by Rocaltrol Capsule.
If you have kidney issues, which Rocaltrol Capsule helps manage, limit the intake of high-potassium foods like bananas and oranges. Always consult your doctor for specific dietary recommendations.

Fact Box

Drug Category	Vitamin D Analog
Therapeutic Category	Vitamin D Supplement
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Chronic Kidney Disease, Hypoparathyroidism, Postmenopausal Osteoporosis

What is Rocaltrol Capsule used for?

Rocaltrol Capsule manages low blood calcium levels and bone disorders linked with chronic kidney disease, hypoparathyroidism, and postmenopausal osteoporosis.

How does Rocaltrol Capsule work?

The calcitriol in Rocaltrol Capsule binds to receptors in the body, increasing calcium absorption, stimulating bone mineralisation, and reducing parathyroid hormone synthesis.

How should I take Rocaltrol Capsule?

Rocaltrol Capsule is taken orally with or without food. Always follow your doctor's instructions on dosage and frequency.

What precautions should be taken when using Rocaltrol Capsule?

Avoid use if allergic to calcitriol, or if you have high calcium levels, malabsorption syndrome or a history of kidney stones.

Are there any side effects of Rocaltrol Capsule?

Potential side effects include high calcium levels in the blood or urine, nausea, vomiting, constipation, confusion, muscle weakness and bone pain.

Can other medicines interact with Rocaltrol Capsule?

Yes. Medicines like thiazide diuretics, digitalis, cholestyramine and colestipol, mineral oil and orlistat, and ketoconazole may interact with Rocaltrol Capsule.

How should I store my Rocaltrol Capsules?

Store at room temperature between 20°C to 25°C. Protect from light and moisture, and keep away from children.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

3 Corporate Park , Sion-Trombay Road , Chembur, Mumbai 400 071 India

Country of origin: INDIA

References

U.S. Food and Drug Administration. (1998). Rocaltrol (Calcitriol) NDA #021068. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/98/021068a_appltr_prntlbl.pdf
Roche Hexagon. (1998). ROCALTROL brand of calcitriol CAPSULES and ORAL SOLUTION. https://www.accessdata.fda.gov/drugsatfda_docs/label/1998/21068lbl.pdf
DailyMed - CALCITRIOL- calcitriol 0.25 mcg capsule. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c3d5546b-ccd4-4988-9d86-9f0b29e12128
Calcitriol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00136
Calcitriol: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682335.html

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