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Nebivolol + S-amlodipine

Uses of Nebivolol + S-amlodipine

  • Nebivolol + S-Amlodipine is primarily used for managing hypertension and belongs to the category of cardioselective beta-blockers and calcium channel blockers.

  • This combination can also be employed as a substitute in patients who are already being treated with separate tablets of nebivolol and S-amlodipine.

Side effects of Nebivolol + S-amlodipine

  • Headache

  • Fatigue

  • Dizziness

  • Slow heart rate (Bradycardia)

  • Fluid retention (Oedema)

How Nebivolol + S-amlodipine works

  • Nebivolol + S-Amlodipine is a combination medication used for managing hypertension.

  • Nebivolol is a third-generation beta-blocker. It works by selectively blocking beta-1 receptors in the heart. This reduces heart rate and the force of the heart's contraction, thereby lowering the heart's workload and its demand for oxygen. Moreover, it stimulates nitric oxide release, causing blood vessels to dilate or widen.

  • S-Amlodipine is a calcium channel blocker. It inhibits L-type calcium channels in vascular smooth muscle cells and the heart muscle, preventing calcium from entering these cells. This causes the arterial muscles to relax, thereby reducing peripheral vascular resistance and lowering blood pressure. It also dilates coronary arteries and arterioles.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Nebivolol + S-Amlodipine is available for oral administration in the form of tablets.

Age and Dose Restrictions

  • This medication is primarily meant for adults.

  • It may also be used in adolescents aged 18 and above.

Contraindications

  • Nebivolol + S-Amlodipine is contraindicated in patients with severe bradycardia or heart block, decompensated heart failure, severe hepatic impairment (Child-Pugh class C), and a history of bronchial asthma or severe COPD.

  • It should not be used by individuals with known hypersensitivity to either component of the medicine.

Other Medications to Avoid

  • Nebivolol + S-Amlodipine may interact with other blood pressure lowering medicines (such as enalapril, losartan), certain calcium channel blockers (such as diltiazem, verapamil), and beta-blockers (such as metoprolol, propranolol). It can also interact with medications affecting liver enzymes (such as ketoconazole, rifampin), and other antihypertensive agents (such as clonidine, hydralazine).

Overdose and Missed Dose

  • Overdosing on Nebivolol + S-Amlodipine may lead to severe hypotension and slow heart rate. Contact your doctor immediately if you suspect an overdose.

  • If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Headaches can be managed by drinking plenty of water and resting in a dark, quiet room.

  • Fatigue can be managed by adjusting the timing of medication to bedtime.

  • Peripheral oedema can be managed with leg elevation and reducing salt intake.

Use in Driving and Operating Machinery

  • Nebivolol + S-Amlodipine may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Consult your doctor before using Nebivolol + S-Amlodipine during pregnancy or while breastfeeding. The potential risks and benefits should be thoroughly discussed.

Caution in Other Conditions

  • Nebivolol + S-Amlodipine should be used with caution in patients with severe renal impairment, moderate hepatic impairment, peripheral vascular disease or Raynaud's syndrome, metabolic syndrome or diabetes mellitus, thyrotoxicosis, and depression.

Special Dietary and Lifestyle Recommendations

  • Following a low-salt diet can help control high blood pressure.

  • Regular physical activity is recommended to manage hypertension effectively.

  • Reduction in alcohol consumption can also help in managing high blood pressure.

  • Limiting caffeine intake may help decrease blood pressure levels.

  • A balanced diet rich in fruits, vegetables, whole grains, lean proteins and low-fat dairy products should be part of your lifestyle.

Frequently asked questions

No, Nebivolol + S-Amlodipine is not designed or recommended for weight loss. It is a medication primarily used to manage hypertension.

Though it is unlikely, mood changes are a potential side effect of many medications, including Nebivolol + S-Amlodipine. If you notice significant emotional changes after starting this medication, consult your doctor.

Certain skin reactions could occur as a rare side effect of Nebivolol + S-Amlodipine. If you notice any unusual skin symptoms while taking this medication, contact your doctor immediately.

Yes, regular activity and exercise are generally encouraged even if you are taking Nebivolol + S-Amlodipine. However, heavy exercise might affect your blood pressure, so it is best to discuss your exercise routine with your doctor.

Certain herbal supplements could interact with Nebivolol + S-Amlodipine and affect its effectiveness or safety. Always consult your doctor before starting any new supplements while on this medication.

No direct link has been established between Nebivolol + S-Amlodipine and changes in menstrual cycle. If you notice irregularities in your menstrual cycle after starting this medication, consult your doctor.

Moderate alcohol consumption should not significantly affect the action of Nebivolol + S-Amlodipine. However, excessive alcohol may enhance some of the side effects of this medication, such as light-headedness or dizziness. It is always best to consult your doctor about alcohol use while on this medication.

Terms & Conditions


Available medicines for NEBIVOLOL + S-AMLODIPINE
Amlovas Sn 5/2.5 MG Tablet 10
Amlovas Sn 5/2.5 MG Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
â‚ą51.22
MRP â‚ą62.46
18.00% OFF
Nebicard Sm Tablet 10
Nebicard Sm Tablet 10
Torrent Pharmaceuticals Ltd.
Pack of 10 Units
â‚ą190.81
MRP â‚ą232.70
18.00% OFF
Nebivol Sa Tablet 10
Nebivol Sa Tablet 10
Knoll Healthcare Pvt. Ltd.
Pack of 10 Units
â‚ą84.98
MRP â‚ą170.30
50.10% OFF
Nebistar Sa Tablet 15
Nebistar Sa Tablet 15
Lupin Ltd
Pack of 15 Units
â‚ą309.26
MRP â‚ą377.15
18.00% OFF
Cardiolol S 5/2.5 MG Tablet 10
Cardiolol S 5/2.5 MG Tablet 10
Cubit Healthcare
Pack of 10 Units
â‚ą103.73
MRP â‚ą126.50
18.00% OFF
Nebicure Sa Tablet 10
Nebicure Sa Tablet 10
Accilex Nutricorp
Pack of 10 Units
â‚ą65.60
MRP â‚ą80.00
18.00% OFF
Asivol A 5/2.5mg Tablet 10
Asivol A 5/2.5mg Tablet 10
As Pharmaceutical (india) Pvt Ltd
Pack of 10 Units
â‚ą56.58
MRP â‚ą69.00
18.00% OFF
Nubeta Sm Tablet 10
Nubeta Sm Tablet 10
Abbott Healthcare Pvt. Ltd
Pack of 10 Units
â‚ą153.44
MRP â‚ą187.12
18.00% OFF

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