Nebivolol + S-Amlodipine is primarily used for managing hypertension and belongs to the category of cardioselective beta-blockers and calcium channel blockers.
This combination can also be employed as a substitute in patients who are already being treated with separate tablets of nebivolol and S-amlodipine.
Headache
Fatigue
Dizziness
Slow heart rate (Bradycardia)
Fluid retention (Oedema)
Nebivolol + S-Amlodipine is a combination medication used for managing hypertension.
Nebivolol is a third-generation beta-blocker. It works by selectively blocking beta-1 receptors in the heart. This reduces heart rate and the force of the heart's contraction, thereby lowering the heart's workload and its demand for oxygen. Moreover, it stimulates nitric oxide release, causing blood vessels to dilate or widen.
S-Amlodipine is a calcium channel blocker. It inhibits L-type calcium channels in vascular smooth muscle cells and the heart muscle, preventing calcium from entering these cells. This causes the arterial muscles to relax, thereby reducing peripheral vascular resistance and lowering blood pressure. It also dilates coronary arteries and arterioles.
Doctor of Medicine
BMS, FMC, MD Resident
Nebivolol + S-Amlodipine is available for oral administration in the form of tablets.
This medication is primarily meant for adults.
It may also be used in adolescents aged 18 and above.
Nebivolol + S-Amlodipine is contraindicated in patients with severe bradycardia or heart block, decompensated heart failure, severe hepatic impairment (Child-Pugh class C), and a history of bronchial asthma or severe COPD.
It should not be used by individuals with known hypersensitivity to either component of the medicine.
Nebivolol + S-Amlodipine may interact with other blood pressure lowering medicines (such as enalapril, losartan), certain calcium channel blockers (such as diltiazem, verapamil), and beta-blockers (such as metoprolol, propranolol). It can also interact with medications affecting liver enzymes (such as ketoconazole, rifampin), and other antihypertensive agents (such as clonidine, hydralazine).
Overdosing on Nebivolol + S-Amlodipine may lead to severe hypotension and slow heart rate. Contact your doctor immediately if you suspect an overdose.
If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for the missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Headaches can be managed by drinking plenty of water and resting in a dark, quiet room.
Fatigue can be managed by adjusting the timing of medication to bedtime.
Peripheral oedema can be managed with leg elevation and reducing salt intake.
Nebivolol + S-Amlodipine may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery.
Consult your doctor before using Nebivolol + S-Amlodipine during pregnancy or while breastfeeding. The potential risks and benefits should be thoroughly discussed.
Nebivolol + S-Amlodipine should be used with caution in patients with severe renal impairment, moderate hepatic impairment, peripheral vascular disease or Raynaud's syndrome, metabolic syndrome or diabetes mellitus, thyrotoxicosis, and depression.
Following a low-salt diet can help control high blood pressure.
Regular physical activity is recommended to manage hypertension effectively.
Reduction in alcohol consumption can also help in managing high blood pressure.
Limiting caffeine intake may help decrease blood pressure levels.
A balanced diet rich in fruits, vegetables, whole grains, lean proteins and low-fat dairy products should be part of your lifestyle.
Frequently asked questions
No, Nebivolol + S-Amlodipine is not designed or recommended for weight loss. It is a medication primarily used to manage hypertension.
Though it is unlikely, mood changes are a potential side effect of many medications, including Nebivolol + S-Amlodipine. If you notice significant emotional changes after starting this medication, consult your doctor.
Certain skin reactions could occur as a rare side effect of Nebivolol + S-Amlodipine. If you notice any unusual skin symptoms while taking this medication, contact your doctor immediately.
Yes, regular activity and exercise are generally encouraged even if you are taking Nebivolol + S-Amlodipine. However, heavy exercise might affect your blood pressure, so it is best to discuss your exercise routine with your doctor.
Certain herbal supplements could interact with Nebivolol + S-Amlodipine and affect its effectiveness or safety. Always consult your doctor before starting any new supplements while on this medication.
No direct link has been established between Nebivolol + S-Amlodipine and changes in menstrual cycle. If you notice irregularities in your menstrual cycle after starting this medication, consult your doctor.
Moderate alcohol consumption should not significantly affect the action of Nebivolol + S-Amlodipine. However, excessive alcohol may enhance some of the side effects of this medication, such as light-headedness or dizziness. It is always best to consult your doctor about alcohol use while on this medication.
Nebivolol + S-amlodipine in other salts
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