Nebivolol + S-amlodipine

Dosage Forms Available

• Nebivolol + S-Amlodipine is available for oral administration in the form of tablets.

Age and Dose Restrictions

• This medication is primarily meant for adults.

• It may also be used in adolescents aged 18 and above.

Contraindications

• Nebivolol + S-Amlodipine is contraindicated in patients with severe bradycardia or heart block, decompensated heart failure, severe hepatic impairment (Child-Pugh class C), and a history of bronchial asthma or severe COPD.

• It should not be used by individuals with known hypersensitivity to either component of the medicine.

Other Medications to Avoid

• Nebivolol + S-Amlodipine may interact with other blood pressure lowering medicines (such as enalapril, losartan), certain calcium channel blockers (such as diltiazem, verapamil), and beta-blockers (such as metoprolol, propranolol). It can also interact with medications affecting liver enzymes (such as ketoconazole, rifampin), and other antihypertensive agents (such as clonidine, hydralazine).

Overdose and Missed Dose

• Overdosing on Nebivolol + S-Amlodipine may lead to severe hypotension and slow heart rate. Contact your doctor immediately if you suspect an overdose.

• If you miss a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Headaches can be managed by drinking plenty of water and resting in a dark, quiet room.

• Fatigue can be managed by adjusting the timing of medication to bedtime.

• Peripheral oedema can be managed with leg elevation and reducing salt intake.

Use in Driving and Operating Machinery

• Nebivolol + S-Amlodipine may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Consult your doctor before using Nebivolol + S-Amlodipine during pregnancy or while breastfeeding. The potential risks and benefits should be thoroughly discussed.

Caution in Other Conditions

• Nebivolol + S-Amlodipine should be used with caution in patients with severe renal impairment, moderate hepatic impairment, peripheral vascular disease or Raynaud's syndrome, metabolic syndrome or diabetes mellitus, thyrotoxicosis, and depression.

Special Dietary and Lifestyle Recommendations

• Following a low-salt diet can help control high blood pressure.

• Regular physical activity is recommended to manage hypertension effectively.

• Reduction in alcohol consumption can also help in managing high blood pressure.

• Limiting caffeine intake may help decrease blood pressure levels.

• A balanced diet rich in fruits, vegetables, whole grains, lean proteins and low-fat dairy products should be part of your lifestyle.