Acarbose + Metformin
Uses of Acarbose + Metformin
Acarbose + Metformin is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus and belongs to the group of anti-diabetic medications.
This combination is particularly useful when diet and exercise alone does not provide adequate control over blood sugar levels.
Side effects of Acarbose + Metformin
Nausea
Diarrhoea
Flatulence (gas)
Abdominal pain
Rash or itching
How Acarbose + Metformin works
Acarbose + Metformin is an antidiabetic combination.
Acarbose, one of the ingredients, is an alpha-glucosidase inhibitor. It works by slowing down how the intestines break down complex carbohydrates into simple sugars. This means that less sugar goes into your bloodstream and your blood sugar levels do not rise as much after meals.
Metformin, the second ingredient, is a biguanide. It acts in several ways: it reduces the amount of sugar your liver makes, it decreases the amount of sugar your gut absorbs from food, and it makes your body more sensitive to insulin. This means your body can use insulin more effectively to remove sugar from your blood.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Acarbose + Metformin is available for oral administration in the form of tablets.
Age and Dose Restrictions
This medicine is primarily meant for adults. It may be prescribed to children above 12 years of age under specific circumstances, as advised by the doctor.
Contraindications
Acarbose + Metformin is contraindicated in patients with known hypersensitivity to acarbose or metformin.
This medicine should not be used by patients with severe renal impairment or those with severe hepatic dysfunction.
Patients with diabetic ketoacidosis should avoid using this combination.
Conditions that may cause tissue hypoxia like cardiovascular collapse, severe infection, and acute myocardial infarction also serve as contraindications.
Other Medications to Avoid
Acarbose + Metformin may interact with insulin and other antidiabetic medications (such as glipizide, glyburide), diuretics (such as furosemide, hydrochlorothiazide), corticosteroids (such as prednisone, dexamethasone), thyroid hormones (such as levothyroxine), calcium channel blockers (such as amlodipine, nifedipine), and nonsteroidal anti-inflammatory drugs (NSAIDs) (such as ibuprofen, naproxen).
Overdose and Missed Dose
Overdose of this combination may lead to lactic acidosis, mainly due to metformin. If you suspect an overdose, immediately consult your doctor.
If you miss a dose of this medication, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects of Acarbose + Metformin are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage gastrointestinal side effects like diarrhoea and nausea.
Maintaining a regular eating schedule can help manage flatulence and abdominal pain.
Use in Driving and Operating Machinery
Acarbose + Metformin does not usually affect your ability to drive or operate heavy machinery. However, if you experience dizziness or lightheadedness after taking this medication, you should avoid such activities.
Use in Pregnancy and Lactation
The use of Acarbose + Metformin during pregnancy and breastfeeding should be based on the doctor's advice.
Caution in Other Conditions
Patients with acute or chronic metabolic acidosis should exercise caution when taking Acarbose + Metformin.
This medicine should be used with care in patients with temporary metabolic stresses like fever or trauma.
Special Dietary and Lifestyle Recommendations
Regular monitoring of blood sugar levels is recommended for patients with diabetes.
Maintaining a healthy and balanced diet, and avoiding high sugar foods and drinks can help manage blood sugar levels.
Regular physical activity or exercise can help control blood sugar levels.
Limiting alcohol intake is important as alcohol consumption can affect blood glucose levels.
Regular health screenings and check-ups are recommended to monitor the progress of the patient's condition.
Frequently asked questions
Does Acarbose + Metformin result in weight loss?
There is no clear evidence that Acarbose + Metformin directly causes weight loss. However, it may help to manage weight as it aids in the control of blood sugar spikes after meals, which can indirectly influence weight control. It is important to remember that a healthy diet and regular exercise are also crucial in managing diabetes and maintaining a healthy weight.
Can I stop taking Acarbose + Metformin once my blood sugar levels are under control?
No, you should not stop taking Acarbose + Metformin without consulting your doctor. The medication is meant to manage your blood sugar levels consistently. If you stop taking it suddenly, your blood sugar levels might increase again. Your doctor will guide you on how to manage your medication based on your health condition.
Is Acarbose + Metformin safe to use for a long time?
Acarbose + Metformin is generally safe for long-term use if taken as directed by your doctor. Regular monitoring of kidney function and blood glucose levels is advised while using this medicine.
Can I take Acarbose + Metformin if I have liver disease?
If you have severe liver disease, you should not take Acarbose + Metformin as it can potentially exacerbate the condition. Always inform your doctor about any underlying health conditions before initiating any medication.
Will taking Acarbose + Metformin affect my mood or energy levels?
There is no specific data suggesting that Acarbose + Metformin can directly affect mood or energy levels. However, controlling blood sugar levels effectively can generally improve overall health, wellbeing and energy levels.
Can I take vitamin supplements while on Acarbose + Metformin?
Yes, you can take vitamin supplements while on Acarbose + Metformin. However, Metformin may lower Vitamin B12 levels. Hence, monitoring of Vitamin B12 levels is recommended. Always consult your doctor before starting any new supplements.
Can Acarbose + Metformin cause skin reactions?
Yes, in rare cases, Acarbose + Metformin can cause skin reactions like rash, urticaria (hives), and itching. If you experience any such symptoms, contact your doctor immediately.
Acarbose + Metformin in other salts
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