Acetylcysteine + Vitamin B6 / Pyridoxine

Dosage Forms Available

• Acetylcysteine + Vitamin B6 / Pyridoxine can be taken orally (tablets, capsules, and effervescent granules).

Age and Dose Restrictions

• Acetylcysteine + Vitamin B6 / Pyridoxine is meant for adults and children above the age of 12 years.

Contraindications

• Acetylcysteine + Vitamin B6 / Pyridoxine is contraindicated in individuals with known hypersensitivity to either Acetylcysteine or Pyridoxine.

• It is also contraindicated in individuals with active peptic ulcer disease and those with hereditary fructose intolerance, especially when taking the effervescent granule formulation.

Other Medications to Avoid

• Acetylcysteine + Vitamin B6 / Pyridoxine may interact with antitussives (such as codeine and dextromethorphan) and antibiotics (like ampicillin, erythromycin and tetracycline).

Overdose and Missed Dose

• Overdosing on Acetylcysteine + Vitamin B6 / Pyridoxine may cause adverse effects such as nausea, vomiting, diarrhoea, abdominal pain and could potentially lead to kidney stones or severe sensory neuropathy. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one. Do not double your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless, resolving when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of fluids may help manage side effects such as nausea, vomiting, or diarrhoea.

• Taking this medication with food may help lessen stomach-related side effects.

Use in Driving and Operating Machinery

• Acetylcysteine + Vitamin B6 / Pyridoxine may cause dizziness or drowsiness. If you experience these side effects, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Consult your doctor before using Acetylcysteine + Vitamin B6 / Pyridoxine during pregnancy and breastfeeding.

Caution in Other Conditions

• Patients with asthma should exercise caution when taking Acetylcysteine as it can potentially cause bronchospasm.

• Caution should also be taken by patients with bleeding disorders as this combination may increase the risk of bleeding.

Special Dietary and Lifestyle Recommendations

• To manage Chronic Kidney Disease (CKD), limit high-sodium foods, avoid high-protein diets and maintain a balanced diet that includes adequate amounts of vitamins and minerals.

• A heart-healthy lifestyle including regular exercise, maintaining a healthy weight, and consuming a balanced diet rich in fruits, vegetables, lean proteins, and whole grains can help manage elevated homocysteine levels.