Alfuzosin
Uses of Alfuzosin
The primary use of Alfuzosin is for the management of symptoms associated with benign prostatic hyperplasia, a condition characterized by the noncancerous enlargement of the prostate gland in men. This medication is part of a group of medicines known as alpha-1 adrenergic receptor blockers or alpha blockers.
Side effects of Alfuzosin
Dizziness
Fatigue
Nausea
Abdominal pain
Decreased sexual desire or performance
How Alfuzosin works
Alfuzosin is an Alpha-1 Adrenergic Receptor Blocker.
This medicine works by selectively binding to and blocking the alpha-1 adrenergic receptors found in specific areas. These include the prostate gland, prostatic capsule, bladder neck, and prostatic urethra.
By inhibiting these receptors, Alfuzosin allows the smooth muscles in these tissues to relax. This action helps improve urine flow and alleviates the symptoms associated with a condition called benign prostatic hyperplasia (BPH), which is an enlargement of the prostate gland.
It is important to note that Alfuzosin helps manage BPH symptoms but does not reduce the size of the prostate gland.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Alfuzosin can be taken orally in the form of extended-release tablets.
Age and Dose Restrictions
This medicine is typically recommended for adult men.
Contraindications
Alfuzosin is contraindicated in patients with known allergies to alfuzosin or any of its constituents. It is also contraindicated in patients with moderate to severe liver impairment, severe kidney impairment, and those taking other alpha blockers or medications for erectile dysfunction.
Other Medications to Avoid
Alfuzosin may interact with other alpha blockers (e..g, doxazosin, tamsulosin), medications for erectile dysfunction (e..g, sildenafil, tadalafil), certain antifungals (e.g., ketoconazole, itraconazole), specific antibiotics (clarithromycin, telithromycin), HIV protease inhibitors (e.g., ritonavir), and antidepressants (e.g., nefazodone).
Overdose and Missed Dose
An overdose of Alfuzosin may lead to severe symptoms like extreme dizziness, fainting, and low blood pressure. Immediate medical attention should be sought in case of overdose.
If you miss a dose of this medicine, take it as soon as you remember. However, skip the missed dose if it is nearly time for your next scheduled dose. Do not double up the dose to make up for the missed one.
Management of Side Effects
Most side effects are temporary and usually resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.
Drinking plenty of water can help manage side effects like dizziness and headache.
Rest and relaxation techniques can assist in managing fatigue or tiredness caused by this medicine.
Use in Driving and Operating Machinery
Alfuzosin may cause dizziness or fatigue. Hence, it is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you.
Use in Pregnancy and Lactation
Alfuzosin is recommended for adult men and therefore it's not applicable for pregnant or lactating women.
Caution in Other Conditions
Patients with liver or heart problems should take Alfuzosin with caution. Caution should also be exercised if you are scheduled for cataract or glaucoma surgery. In these situations, your doctor may recommend a different treatment plan or a more frequent monitoring routine.
Special Dietary and Lifestyle Recommendations
Limiting caffeine and alcohol intake can help reduce urinary symptoms associated with BPH.
Practice "double voiding" – urinate as much as possible, relax for a moment, then urinate again – to help empty the bladder completely.
Frequently asked questions
Is Alfuzosin a type of steroid medicine?
No, Alfuzosin is not a steroid. It belongs to a class of medications known as alpha-1 adrenergic receptor blockers or alpha blockers.
Can Alfuzosin affect my sleep patterns?
Alfuzosin may cause drowsiness in some people, but it does not typically disrupt normal sleep patterns. However, if you experience severe sleep disturbances, do consult your doctor immediately.
Will taking Alfuzosin have any impact on fertility?
Alfuzosin has not been shown to significantly affect fertility in men. However, this medicine can cause decreased libido or erectile dysfunction in some cases, which might indirectly influence fertility.
While I am on Alfuzosin, do I need to follow any specific dietary rules?
No specific dietary restrictions are necessary while taking Alfuzosin. However, it is generally recommended that you take this medication immediately after the same meal each day to enhance its effectiveness.
Is it safe for me to take Alfuzosin every day?
Yes, it is safe to take Alfuzosin daily as directed by your doctor. Always follow your doctor's instructions about the duration and dosage of this medication.
After I take my dose of Alfuzosin, how long does it usually take for the medicine to start working?
The exact time can vary depending on individual responses, but generally, you should start noticing improvement in your symptoms within a few days to weeks of starting Alfuzosin treatment.
Is there an alternative to Alfuzosin for managing benign prostatic hyperplasia?
There are several alternatives to Alfuzosin for managing BPH, including other alpha blockers and medications like 5-alpha reductase inhibitors. However, the right medication for you should be decided by your doctor based on your specific condition and health history.
Alfuzosin in other salts
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