Home/Drugs By Ailments / Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine)

Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine)

Uses of Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine)

  • The primary use of Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (Pyridoxine) is the management of neuropathic pain, more specifically in treatment of painful symptoms of diabetic neuropathy and other nerve pain. This medicine belongs to the group of neuroprotective and pain-modulating medications.

Side effects of Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine)

  • Dizziness

  • Drowsiness

  • Headache

  • Blurred vision

  • Dry mouth

How Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine) works

  • Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (Pyridoxine) is a neuroprotective and pain-modulating combination used for managing neuropathic pain.

  • Alpha Lipoic Acid is a potent antioxidant. It protects brain and nerve tissues, helping to delay or reverse nerve cell damage.

  • Folic Acid provides crucial nutrients to nerves and assists in cell division and DNA synthesis.

  • Methylcobalamin is an active form of Vitamin B12, assisting in the formation and regeneration of nerve cells. It plays a role in the production of the myelin sheath, which serves as a protective layer for nerve fibres.

  • Pregabalin acts as an anticonvulsant and pain modulator. By binding to voltage-gated calcium channels in nerves, it reduces the release of neurotransmitters that signal pain.

  • Vitamin B6 (Pyridoxine) has an essential role in nerve function and the synthesis of neurotransmitters. It also serves as a coenzyme in various metabolic processes within the body.

  • Together, these ingredients work synergistically to provide neuropathic pain relief and neuroprotection.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (Pyridoxine) is available in capsule form.

Age and Dose Restrictions

  • This combination is intended for use by adults.

Contraindications

  • This combination is contraindicated for individuals with severe renal impairment.

  • It is also contraindicated in those who have a known hypersensitivity to any of the individual components of the formula.

Other Medications to Avoid

  • This combination may interact with central nervous system depressants (such as opioids, benzodiazepines, and alcohol), antidiabetic medicines (like sulfonylureas and meglitinides), medications affecting liver enzymes (such as rifampicin and cimetidine), and anti-Parkinson medications (such as levodopa).

Overdose and Missed Dose

  • An overdose may lead to symptoms such as dizziness, drowsiness, confusion, and blurred vision. If these occur, it is crucial to contact a doctor immediately.

  • If you miss a dose of this combination, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten capsule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this combination. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • For dry mouth, sipping water regularly or using sugar-free candies can be helpful.

  • If experiencing constipation, consider increasing dietary fibre and staying hydrated.

Use in Driving and Operating Machinery

  • This combination may impair your ability to drive or operate machinery safely. It is advisable not to engage in such activities if you experience dizziness or blurred vision after taking this medication.

Use in Pregnancy and Lactation

  • The safety of Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (Pyridoxine) during pregnancy or lactation has not been established. It is recommended to consult a doctor before using this combination during these periods.

Caution in Other Conditions

  • Individuals with diabetes should exercise caution when using this medicine owing to the potential risk of weight gain and oedema associated with Pregabalin.

Special Dietary and Lifestyle Recommendations

  • Regular physical activity can help improve blood circulation, which is beneficial for managing conditions like diabetic neuropathy.

  • Avoid excessive alcohol consumption, as it can worsen neuropathic pain.

  • Consider incorporating foods high in antioxidants, such as berries, nuts, and green leafy vegetables, to help combat oxidative stress on nerve tissues.

Frequently asked questions

This combination is primarily used to manage neuropathic pain, particularly in individuals with diabetic neuropathy. However, it could potentially be used for other types of nerve pain as well, depending on the doctor's recommendation.

No, this combination is not a steroid. It consists of vitamins, an antioxidant, and an anticonvulsant which collectively help in managing neuropathic pain.

Yes, due to its pain-relieving properties, it might indirectly improve sleep by reducing discomfort from nerve pain. Pregabalin, one of its ingredients, can also cause drowsiness as a side effect.

No concrete evidence suggests that this combination affects fertility. However, if you are trying to conceive and have concerns, it is best to consult your doctor.

Pregabalin, one of the components, may cause weight gain and oedema in some individuals, particularly those with diabetes. If you experience unusual weight gain while on this medication, consult your doctor for advice.

Yes, it is generally safe to take daily as prescribed by your doctor. The duration of treatment depends on the condition being managed and individual response to the medication.

This combination usually requires a prescription and is not available over the counter due to its specific use in managing neuropathic pain.

Terms & Conditions


Alpha Lipoic Acid + Folic Acid + Methylcobalamin + Pregabalin + Vitamin B6 (pyridoxine) in other salts

ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE) + VITAMIN D3 (CHOLECALCIFEROL)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEASCORBIC ACID + BIOTIN + CALCIUM PANTOTHENATE + FOLIC ACID + METHYLCOBALAMIN + NIACINAMIDE + RIBOFLAVIN + THIAMINE MONONITRATE + ZINC SULPHATEASCORBIC ACID + ELEMENTAL MANGANESE + ELEMENTAL SELENIUM + ELEMENTAL ZINC + FOLIC ACID + NIACINAMIDE + PYRIDOXINE HYDROCHLORIDE + RIBOFLAVIN / VITAMIN B2 + VITAMIN A + VITAMIN EBIOTIN + CYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL CHROMIUM + ELEMENTAL COPPER + ELEMENTAL MANGANESE + FOLIC ACID + GRAPE SEED EXTRACT + IODINE + MAGNESIUM + RIBOFLAVIN / VITAMIN B2 + SELENIUM + THIAMINE / VITAMIN B1 + VITAMIN A / RETINOL + VITAMIN B3 / NIACIN + VITAMIN B5 / PANTOTHENIC ACID + VITAMIN B6 / PYRIDOXINE + VITAMIN C / ASCORBIC ACID + VITAMIN D3 (CHOLECALCIFEROL) + VITAMIN E + ZINCCALCIUM PHOSPHATE + COPPER SULPHATE PENTAHYDRATE + CYANOCOBALAMIN / VITAMIN B12 + D-PANTHENOL + FOLIC ACID + LIGHT MAGNESIUM OXIDE + NICOTINAMIDE + POTASSIUM IODIDE + VITAMIN A + VITAMIN B1 + VITAMIN B2 + VITAMIN D3 (CHOLECALCIFEROL) + ZINC SULPHATE MONOHYDRATECHROMIUM PICOLINATE + CYANOCOBALAMIN + ELEMENTAL SELENIUM + FOLIC ACID + NICOTINAMIDE + PYRIDOXINE HYDROCHLORIDE + ZINC SULPHATE MONOHYDRATEELEMENTAL CALCIUM + L-METHYLFOLATE CALCIUM + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATE + VITAMIN D3 (CHOLECALCIFEROL)METHYLCOBALAMIN + PREGABALINFERROUS ASCORBATE + FOLIC ACIDFOLIC ACIDRIBOFLAVIN + PYRIDOXINE + VITAMIN B12 + NIACINAMIDE + CALCIUM + FOLIC ACID + BIOTIN + ASCORBIC ACIDMETHYLCOBALAMINPREGABALINL METHYL FOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEPREGABALIN + NORTRIPTYLINEPREGABALIN + NORTRIPTYLINE + METHYLCOBALAMINGABAPENTIN + METHYLCOBALAMINBIOTIN + FOLIC ACIDL METHYLFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEFOLIC ACID + IRON + ZINCDOCOSAHEXAENOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + BENFOTIAMINE + FOLIC ACID + INOSITOL + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)DULOXETINE + METHYLCOBALAMINALPHA LIPOIC ACID + BENFOTIAMINE + ELEMENTAL CHROMIUM + INOSITOL + METHYLCOBALAMINFOLIC ACID + IRONDOCOSAHEXAENOIC ACID + L METHYLFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATECYANOCOBALAMIN / VITAMIN B12 + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDALPHA LIPOIC ACID + GABAPENTIN + METHYLCOBALAMINELEMENTAL IRON + FOLIC ACID + GLYCINEALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + THIAMINE MONONITRATE + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + METHYLCOBALAMINALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + ELEMENTAL CHROMIUM + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINEFOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 / PYRIDOXINE + VITAMIN D3 (CHOLECALCIFEROL)FERROUS FUMARATE + FOLIC ACIDALPHA LIPOIC ACID + BENFOTIAMINE + BIOTIN + CHROMIUM PICOLINATE + FOLIC ACID + METHYLCOBALAMIN + VITAMIN B6 (PYRIDOXINE)ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PYRIDOXINE HYDROCHLORIDE + VITAMIN D3 (CHOLECALCIFEROL)FERROUS ASCORBATE + FOLIC ACID + ZINC SULPHATECYANOCOBALAMIN / VITAMIN B12 + FERRIC AMMONIUM CITRATE + FOLIC ACIDCAPSAICIN + DICLOFENAC DIETHYLAMINE + MENTHOL + METHYL SALICYLATE + PREGABALINCYANOCOBALAMIN + L-LYSINE + NICOTINAMIDE + SORBITOL + VITAMIN B6 (PYRIDOXINE)METHYLCOBALAMIN + NICOTINAMIDE + VITAMIN B6 / PYRIDOXINED-PANTHENOL + METHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINEMETHYLCOBALAMIN + NIACINAMIDE + VITAMIN B6 / PYRIDOXINECYANOCOBALAMIN + ELEMENTAL IRON + ELEMENTAL ZINC + FOLIC ACIDCYANOCOBALAMIN + ELEMENTAL IRON + FOLIC ACIDFERROUS ASCORBATE + FOLIC ACID + METHYLCOBALAMINACECLOFENAC + PREGABALINEPALRESTAT + METHYLCOBALAMINDOXYLAMINE + FOLIC ACID + VITAMIN B6 / PYRIDOXINEALPHA LIPOIC ACID + METFORMINCALCIUM-5 METHYLTETRAHYDROFOLATE + METHYLCOBALAMIN + PYRIDOXAL 5 PHOSPHATEFOLIC ACID + LACTIC ACID BACILLUS + NIACINAMIDE + RIBOFLAVIN / VITAMIN B2CALCIUM CITRATE + FOLIC ACID + VITAMIN D3 (CHOLECALCIFEROL)DIACEREIN + GLUCOSAMINE SULFATE POTASSIUM CHLORIDE + METHYL SULFONYL METHANE + METHYLCOBALAMINDOXYLAMINE + FOLIC ACID + VITAMIN B6 (PYRIDOXINE)
Available medicines for ALPHA LIPOIC ACID + FOLIC ACID + METHYLCOBALAMIN + PREGABALIN + VITAMIN B6 (PYRIDOXINE)
Pregalon Capsule 10
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