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Alprazolam + Fluoxetine

Uses of Alprazolam + Fluoxetine

  • Alprazolam + Fluoxetine is primarily used for the management of major depressive disorder (MDD). It belongs to the group of benzodiazepines and selective serotonin reuptake inhibitor (SSRI) antidepressants.

  • Besides MDD, this combination medicine may also be used in certain cases to manage generalised anxiety disorder (GAD), panic disorder, and obsessive-compulsive disorder (OCD).

Side effects of Alprazolam + Fluoxetine

  • Drowsiness

  • Dizziness

  • Fatigue

  • Dry mouth

  • Changes in appetite or weight

How Alprazolam + Fluoxetine works

  • Alprazolam + Fluoxetine is a psychiatric combination medication.

  • Alprazolam is a benzodiazepine. It amplifies the activity of gamma-aminobutyric acid (GABA), a natural chemical that sends signals throughout your nervous system. When GABA attaches to its receptors in the brain, it reduces the activity of the nerve cells, causing a calming effect on the mind and body.

  • Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin, a neurotransmitter in our brain that helps maintain mental balance. By blocking the reabsorption (reuptake) of serotonin into neurons, more serotonin is available in the synaptic space between neurons, which helps brain cells send and receive chemical messages, boosting mood.

  • Together, these medicines work in harmony to efficiently manage symptoms of anxiety and depression by simultaneously enhancing GABA and serotonin activity in the brain.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Alprazolam + Fluoxetine is available in the form of tablets for oral consumption.

Age and Dose Restrictions

  • This medicine is primarily intended for use in adults. It can also be given to older adolescents, typically those aged 16 years and above, under the supervision of a doctor.

Contraindications

  • Alprazolam + Fluoxetine is contraindicated in patients with known hypersensitivity to either alprazolam or fluoxetine.

  • It cannot be used by patients who have recently (within the last 14 days) taken monoamine oxidase inhibitors (MAOIs).

Other Medications to Avoid

  • Alprazolam + Fluoxetine can interact with benzodiazepines (e.g., diazepam and clonazepam), opioids (e.g., morphine and fentanyl), anticonvulsants (e.g., carbamazepine and phenytoin), antifungal agents (e.g., ketoconazole and itraconazole), and certain antidepressants (e.g., amitriptyline and nortriptyline).

Overdose and Missed Dose

  • Overdose of Alprazolam + Fluoxetine can potentially lead to severe drowsiness, confusion, tremors, convulsions, and even loss of consciousness. In such cases, immediate medical attention is required.

  • If you forget to take a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dose schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If drowsiness or dizziness is experienced, avoid tasks requiring mental alertness, such as operating machinery or driving.

  • For dry mouth, frequent sips of water or sucking on ice cubes may be helpful.

  • Gastrointestinal disturbances may be managed by eating smaller, more frequent meals.

Use in Driving and Operating Machinery

  • Alprazolam + Fluoxetine may cause side effects such as drowsiness and dizziness that can impair your ability to drive or operate machinery. It is advised to avoid such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Alprazolam + Fluoxetine should be used during pregnancy and breastfeeding only if the potential benefit justifies the potential risk to the baby. Always consult your doctor before using this medication during these periods.

Caution in Other Conditions

  • Caution should be exercised when using Alprazolam + Fluoxetine in patients with kidney or liver diseases since these conditions may affect how this medicine is processed in the body.

Special Dietary and Lifestyle Recommendations

  • Regular relaxation and breathing exercises can help manage anxiety and stress.

  • A balanced diet rich in fruits, vegetables, lean proteins, and whole grains can contribute to overall well-being and mental health.

  • Avoid alcohol and caffeine, as they can potentially worsen anxiety and sleep problems associated with depression and anxiety disorders.

  • Regular physical activity can help improve mood and reduce anxiety.

Frequently asked questions

No, Alprazolam + Fluoxetine is not a steroid. It is a combination medicine that contains alprazolam, a benzodiazepine, and fluoxetine, a selective serotonin reuptake inhibitor (SSRI) antidepressant.

Yes, Alprazolam + Fluoxetine may affect your sleep patterns. It can cause insomnia or abnormal dreams as side effects. It is always best to consult your doctor if you notice any changes in your sleep after starting this medicine.

The safety of daily use of Alprazolam + Fluoxetine depends on the individual's health condition and the doctor's prescription. It should be taken as directed by the doctor.

The onset of anti-anxiety effects may be noticed within a few days of starting treatment, while the full antidepressant effect may take several weeks to manifest.

Alprazolam + Fluoxetine can be taken at any time as directed by your doctor, but it is usually recommended to be taken once daily in the morning.

Alprazolam + Fluoxetine is not available over the counter. You will need a valid prescription from a doctor to obtain this medication.

Yes, Alprazolam + Fluoxetine can help manage mood swings, as it is used in managing depression and anxiety disorders. Alprazolam is a benzodiazepine that has calming effects, and fluoxetine acts as an antidepressant.

Terms & Conditions


Available medicines for ALPRAZOLAM + FLUOXETINE
Alzonex Plus 0.25/20 MG Tablet 10
Alzonex Plus 0.25/20 MG Tablet 10
Marc Pharma
Pack of 10 Units
₹40.59
MRP ₹49.50
18.00% OFF
Pronil Forte 0.25/20 MG Capsule 10
Pronil Forte 0.25/20 MG Capsule 10
Psychotropics India Ltd
Pack of 10 Units
₹62.46
MRP ₹76.17
18.00% OFF
F & A 0.25/20 MG Tablet 10
F & A 0.25/20 MG Tablet 10
Midas Care Pharmaceuticals Pvt Ltd
Pack of 10 Units
₹38.54
MRP ₹47.00
18.00% OFF
Faa Plus 0.25/20 MG Tablet 10
Faa Plus 0.25/20 MG Tablet 10
Gentech Healtcare Ltd
Pack of 10 Units
₹56.23
MRP ₹68.57
18.00% OFF
Exiten Plus 0.25/20 MG Tablet 10
Exiten Plus 0.25/20 MG Tablet 10
Synokem Pharmaceuticals Ltd
Pack of 10 Units
₹45.59
MRP ₹55.60
18.00% OFF
Azo F 0.25/20 MG Tablet 10
Azo F 0.25/20 MG Tablet 10
Allenge India
Pack of 10 Units
₹26.24
MRP ₹32.00
18.00% OFF
Cnl Plus 0.25/20 MG Tablet 10
Cnl Plus 0.25/20 MG Tablet 10
Clyde Biotech (p) Ltd
Pack of 10 Units
₹34.85
MRP ₹42.50
18.00% OFF
Eleflu 0.25/20 MG Tablet 10
Eleflu 0.25/20 MG Tablet 10
Lancer Pharmaceuticals Pvt. Ltd
Pack of 10 Units
₹25.58
MRP ₹31.20
18.00% OFF

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