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Ambroxol + Guaifenesin + Levosalbutamol

Expectorants

Uses of Ambroxol + Guaifenesin + Levosalbutamol

  • Ambroxol + Guaifenesin + Levosalbutamol combines three expectorants medicines prescribed for managing productive cough linked with bronchospasm in conditions such as bronchitis and bronchial asthma.
  • It is also indicated for all conditions characterised by persistent mucus, wheezing, and chest congestion.

Side effects of Ambroxol + Guaifenesin + Levosalbutamol

  • Increased heart rate
  • Palpitations 
  • Dizziness 
  • Headache
  • Drowsiness
  • Vomiting
  • Nausea
  • Sweating

How Ambroxol + Guaifenesin + Levosalbutamol works

  • Ambroxol serves as a mucolytic agent. Elevated Nitric oxide (NO) levels are linked to inflammatory processes and specific airway dysfunctions. NO amplifies the activation of soluble guanylate cyclase, leading to increased cGMP accumulation. Ambroxol has demonstrated its ability to inhibit the NO-dependent activation of soluble guanylate cyclase. This inhibition may suppress excessive mucus secretion, thereby reducing phlegm viscosity and enhancing the mucociliary transport of bronchial secretions.
  • Guaifenesin has the potential to act as an irritant to gastric vagal receptors, eliciting efferent parasympathetic reflexes that induce the glandular exocytosis of a less viscous mucus mixture. This process may provoke coughing. The combined effect can help flush out tenacious, congealed mucopurulent material from obstructed small airways, resulting in a transient improvement in dyspnea or the work of breathing.
  • Levosalbutamol induces relaxation in the smooth muscles of all airways, spanning from the trachea to the terminal bronchioles. Elevated cyclic AMP concentrations are linked to the inhibition of mediator release from cells within the airways. Functioning as a functional agonist, levosalbutamol relaxes the airways independent of the specific spasmogen involved, providing protection against various bronchoconstrictor challenges.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Ambroxol + Guaifenesin + Levosalbutamol is available for use via the oral route (syrup, suspension, solution).

Age and Dose Restrictions

  • This combination is meant for adults and children above 2 years of age.

Contraindications

  • Ambroxol + Guaifenesin + Levosalbutamol is contraindicated in patients with known allergies to ambroxol, guaifenesin, levosalbutamol and who have cardiac disease and thyrotoxicosis.

Use In Driving And Operating Machinery

  • Ambroxol + Guaifenesin + Levosalbutamol may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.

Overdose and Missed Dose

  • Overdose of this combination can cause angina, hypertension, tachycardia, nervousness, headache, tremor, palpitations, dry mouth, nausea, dizziness, fatigue, and insomnia. Inform your doctor regarding these effects and follow the advice accordingly.
  • If you forget an Ambroxol + Guaifenesin + Levosalbutamol dose, take it as soon as you remember. However, avoid repeating the dose.

Use in Pregnancy and Lactation

  • Ambroxol + Guaifenesin + Levosalbutamol is not recommended during pregnancy and while breastfeeding.

Other Medications To Avoid With This Medicine

  • The combination of Ambroxol + Guaifenesin + Levosalbutamol may potentially interact with certain medications, and it is crucial to be cautious about concurrent use. Medicines that affect the cardiovascular system, like beta-blockers or other sympathomimetic agents, may have additive effects when combined with levosalbutamol, possibly leading to increased heart rate or blood pressure. Additionally, medications that influence the central nervous system or have sedative effects may interact with levosalbutamol, potentially intensifying side effects such as dizziness or nervousness. It is advisable to avoid concurrent use with monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants, as they may potentiate cardiovascular effects. It is imperative to inform the doctor about all medications, including prescription, over-the-counter, and herbal supplements, to ensure the safe and effective use of Ambroxol + Guaifenesin + Levosalbutamol.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking Ambroxol + Guaifenesin + Levosalbutamol.
  • For individuals taking Ambroxol + Guaifenesin + Levosalbutamol, adopting specific diet and lifestyle practices can complement their respiratory health. Firstly, maintaining proper hydration is crucial, as it helps optimise the effectiveness of mucolytic agents like ambroxol and guaifenesin. Staying well-hydrated can aid in loosening and expelling mucus from the airways. Additionally, individuals are advised to refrain from smoking and minimise exposure to environmental pollutants, as these can exacerbate respiratory conditions.

Frequently asked questions

This combination takes a few minutes to a few hours to work after consumption.

Exercise caution if you are allergic to this combination and have a history of heart, liver or kidney problems.

Do not stop taking this combination without consulting your doctor, even if you feel healthy.

Consult your doctor before taking this combination if you have kidney or liver issues to ensure its safety and proper dosage.

Terms & Conditions


Available medicines for Ambroxol + Guaifenesin + Levosalbutamol
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₹77.60
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