Amiloride + Hydrochlorothiazide

Dosage Forms Available

• Amiloride + Hydrochlorothiazide is available for use via the oral route (tablets).

Age and Dose Restrictions

• This medicine is generally intended for use in adults.

Contraindications

• Amiloride + Hydrochlorothiazide is contraindicated in patients who have known allergies to either amiloride or hydrochlorothiazide.

• It should not be used by individuals with severe kidney disease, difficulty urinating (anuria), or high potassium levels (hyperkalemia).

Other Medications to Avoid

• Amiloride + Hydrochlorothiazide can interact with several medications including potassium supplements and potassium-saving diuretics (such as spironolactone), lithium-containing medicines, certain pain relievers like non-steroidal anti-inflammatory medicines (NSAIDs such as ibuprofen and diclofenac), heart medication (such as digoxin), medications for diabetes (like thiazolidinedione and metformin), and specific cholesterol-lowering medicines (like cholestyramine and colestipol).

Overdose and Missed Dose

• Taking too much Amiloride + Hydrochlorothiazide can lead to serious side effects like dehydration, low blood pressure, and electrolyte imbalances. If you suspect an overdose, seek immediate medical attention.

• If you miss a dose of this medicine, take it when you remember. However, if it is near the time for your next dose, skip the missed dose and continue with your regular schedule. Never double your dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage dizziness, try getting up slowly from a sitting or lying position.

• To manage increased urination, try to take your dose in the morning to avoid disturbing your sleep with frequent trips to the bathroom.

Use in Driving and Operating Machinery

• Some patients may feel dizzy after taking Amiloride + Hydrochlorothiazide. This could affect your ability to drive or operate machinery. If you experience this side effect, please avoid these activities until you feel well enough.

Use in Pregnancy and Lactation

• Amiloride + Hydrochlorothiazide should only be used during pregnancy or breastfeeding if absolutely necessary and the benefits outweigh potential risks. Always consult your doctor before using this medication during these periods.

Caution in Other Conditions

• Due to its diuretic action, Amiloride + Hydrochlorothiazide should be used with caution in patients with liver disease or kidney disease.

• It may also affect sugar levels, so patients with diabetes should monitor their blood sugar regularly while taking this combination.

Special Dietary and Lifestyle Recommendations

• Monitoring your salt intake is important while taking Amiloride + Hydrochlorothiazide as it helps control fluid balance and blood pressure.

• Regular physical activity can help manage hypertension and improve overall health. Seek advice from your doctor about a suitable exercise routine.

• Limit alcohol and caffeine intake as they can increase blood pressure and potentially decrease the effectiveness of this medication.

• It is also beneficial to maintain a potassium-balanced diet while taking this medicine but avoid excessive potassium intake.