Amiodarone
Uses of Amiodarone
Amiodarone is primarily used to manage life-threatening ventricular arrhythmias such as ventricular tachycardia and ventricular fibrillation. It belongs to the group of medicines known as antiarrhythmics.
It is also indicated for the management of atrial fibrillation and atrial flutter. In addition, it can be used for individuals who have had a recent heart attack and are at high risk of developing arrhythmias. Furthermore, Amiodarone is sometimes administered to patients undergoing heart surgery to prevent the occurrence of arrhythmias.
Side effects of Amiodarone
Nausea or vomiting
Loss of appetite
Fatigue or weakness
Insomnia or sleep disturbances
Skin discoloration
How Amiodarone works
Amiodarone is an antiarrhythmic medicine.
It works by blocking potassium channels in the heart, which play a crucial role in maintaining regular heartbeat. This blocking action helps to lengthen the action potential duration and refractory period in heart muscle cells, making them less likely to produce abnormal electrical signals that lead to irregular heartbeats.
Certified content
Written By
Doctor of Medicine
Reviewed By
BAMS, APG, PG
Expert Advice
Dosage Forms Available
Amiodarone can be taken via oral (tablet) and infusion (intravenous) route.
Age and Dose Restrictions
This medication is usually prescribed for adults aged 18 and above.
Contraindications
This medicine is contraindicated in patients with known allergies to Amiodarone.
It should be avoided in patients with severe sinus node dysfunction, cardiogenic shock, or second or third-degree heart block unless they have a functioning artificial pacemaker.
Other Medications to Avoid
Amiodarone can interact with heart medication (such as digoxin), and blood thinning medication (such as warfarin).
Overdose and Missed Dose
An overdose of Amiodarone can result in severe side effects like low blood pressure, heart block, and liver problems. Immediate medical intervention is needed if an overdose is suspected.
If a dose of Amiodarone is missed, it should be taken as soon as remembered. If the time for the next dose is near, then the missed dose should be skipped, and the regular schedule should be continued.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water may help to manage some digestive side effects like constipation.
Skin discolouration can be managed by applying sunscreen and avoiding excessive sun exposure.
Use in Driving and Operating Machinery
Amiodarone may cause dizziness or blurred vision. Therefore, patients should avoid driving or operating heavy machinery until they are sure about their reaction to the medication.
Use in Pregnancy and Lactation
Amiodarone is not generally recommended during pregnancy or breastfeeding. If required, it should only be used under medical supervision.
Caution in Other Conditions
Patients with existing lung, liver or thyroid conditions should exercise extreme caution when taking Amiodarone.
Regular monitoring of these conditions is important while taking this medication.
Special Dietary and Lifestyle Recommendations
Ensure adequate hydration while on the medication.
Regular heart checkups and consistent monitoring of blood pressure are advised.
Frequently asked questions
Can Amiodarone be taken with milk?
No, it is not necessary to take Amiodarone with milk. It can be taken with a full glass of water. This medicine should be swallowed whole and not crushed or chewed.
Does Amiodarone affect blood pressure?
Although Amiodarone is not typically used for managing blood pressure, If you notice symptoms of low blood pressure such as dizziness or fainting, seek immediate medical attention.
Does Amiodarone cause weight gain?
Weight gain is not a common side effect of Amiodarone. However, if you notice unexplained weight gain or swelling in your feet or ankles, contact your doctor as this could be a sign of a serious problem.
Is Amiodarone safe for diabetics?
Amiodarone may be used in patients with diabetes, but close monitoring is necessary. Diabetes can increase the risk of heart disease and arrhythmias, so it is important to control your blood sugar while on this medication.
Is there a natural alternative to Amiodarone?
There are no natural alternatives to Amiodarone that have been shown to be effective for managing arrhythmias. Always consult your doctor before starting any alternative or complementary therapies.
Is Amiodarone vegan-friendly?
The specific composition of amiodarone tablets may vary among manufacturers. It is important to check with your pharmacist or the manufacturer to determine whether a specific brand is suitable for vegans.
What is the best time to take Amiodarone?
Amiodarone should be taken as per your doctor's instructions.
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