Cordarone X 200 Mg Tablet 15

Cordarone X Tablet 15

Sanofi India Ltd.

Strip of 15 Units

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Composition

Amiodarone (200 Mg)

Cordarone X Tablet is used for managing certain serious types of ventricular arrhythmias that are life-threatening when other treatments have failed or are not well-tolerated. This medicine is part of a group known as Class III antiarrhythmic agents.

Beyond its primary use, this tablet is also employed to prevent the recurrence of these ventricular arrhythmias. By managing these arrhythmias, it helps to maintain a regular heart rhythm which is crucial for proper heart function and overall health.

Before starting this medicine, you should consult your doctor who will decide the appropriate dosage and frequency based on your specific condition. It's important to let your doctor know about any pre-existing health conditions or ongoing medications. If while taking this medicine, you notice any side effects, do inform your doctor right away.

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Cordarone X Tablet is used for the following:

Managing life-threatening recurrent ventricular arrhythmias
Controlling serious heart rhythm disorders that haven't responded to other treatments

Directions for Use of Cordarone X Tablet 15

Here's how to take Cordarone X Tablet:

Swallow the tablet whole with a glass of water.
Avoid breaking, crushing, or chewing the tablet.
Take this medicine as advised by your doctor; do not go beyond the instructed dose.
It's crucial not to stop taking this medicine without first consulting your doctor.

Cordarone X Tablet is taken orally.

Cordarone X Tablet may have the following side effects:

Pulmonary toxicity: This refers to a condition where your lungs might get damaged, which can cause symptoms like shortness of breath and coughing.
Hepatotoxicity: This means that the tablet could have harmful effects on your liver, leading to elevated liver enzymes.
Thyroid dysfunction: This could result in either hypothyroidism, where your thyroid gland does not produce enough hormones, or hyperthyroidism, when it produces too many.
Bradycardia: Meaning your heart rate might become slower than usual.
Visual disturbances: This could include deposits on the cornea, halos around lights or blurred vision.
Gastrointestinal disturbances: Such as nausea, vomiting and loss of appetite.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Cordarone X Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Hepatotoxicity: If you experience symptoms related to liver damage, consult your doctor immediately.
Gastrointestinal disturbances: If you feel nauseous or lose your appetite after taking this medicine, try having it after meals to lessen these effects.

Cordarone X Tablet contains amiodarone (200 mg) and it works in the following ways:

Prolongation of Cell-Action Potential: Amiodarone lengthens the period during which your heart muscle cells can conduct electricity. This helps to slow down the heart rate and maintain a regular rhythm.
Noncompetitive Inhibition of α- and β-Adrenergic Receptors: Amiodarone also influences particular receptors in your heart called α- and β-adrenergic receptors. By reducing their activity, it further helps in maintaining regular heart rhythm.

Through these mechanisms, amiodarone in Cordarone X Tablet effectively manages serious ventricular arrhythmias that are life-threatening.

Pregnancy

Cordarone X Tablet is contraindicated during pregnancy. If you are pregnant or planning to become pregnant, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Cordarone X Tablet if you are breastfeeding. It's highly recommended to consult your doctor to understand the potential risks and benefits.

Alcohol

Although there isn't a direct interaction between Cordarone X Tablet and alcohol, it's best to limit alcohol consumption while on this medication. Discuss any concerns with your doctor.

Liver

Liver health issues can be a concern with Cordarone X Tablet, especially as it may affect liver function. If you have liver problems, ensure you have a discussion with your doctor before starting this medication.

Kidney

If you have a history of any kidney problems, caution is advised before using Cordarone X Tablet. Always consult your doctor before taking this medicine.

Using Machines & Driving

Cordarone X Tablet may cause visual disturbances which can affect your ability to drive or operate machinery. It's advisable to avoid such activities if you experience these side effects.

Allergy

If you are allergic to amiodarone or any other ingredients in Cordarone X Tablet, refrain from taking this medicine. Always inform your doctor about any known allergies before starting a new medication.

Children

This medicine is not typically prescribed for children under 18 years of age. Always consult your doctor before giving Cordarone X Tablet to a child.

Older Patients

Older patients should take Cordarone X Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age or have liver and kidney issues, always discuss them with your doctor who will guide you based on your health status.

Drug-Drug Interactions

Cordarone X Tablet interacts with the following medicines:

Beta-blockers: When atenolol or propranolol is combined with this medicine, there is an increased risk of slow heart rate and conduction disturbances.
Statins: Medicines like atorvastatin and simvastatin can have their muscle toxicity enhanced by Cordarone X Tablet.
CYP3A4 inhibitors: Medicines such as ketoconazole or erythromycin can increase amiodarone levels in the body when taken alongside Cordarone X Tablet, enhancing the risk of side effects.

Drug-Food Interactions

Food can enhance the absorption of Cordarone X Tablet. It's a good idea to take your dosage with a meal.

Drug-Disease Interactions

Cordarone X Tablet interacts with the following diseases:

Pulmonary Disease: Amiodarone, present in this medication, has been associated with severe lung damage. If you have any lung condition, be cautious while taking this medicine.
Liver Disease: People with liver disease should be careful as Cordarone X Tablet could worsen their condition.
Thyroid Disorders: Both hypothyroidism and hyperthyroidism may occur during amiodarone therapy. Regular thyroid function tests are advisable when taking this medicine.
Bradycardia and Conduction Disturbances: If you have a slow heart rate or disorders related to electrical conduction within the heart, be careful while taking Cordarone X Tablet.

Daily Dose

Always take the Cordarone X Tablet in the dose and frequency as advised by your doctor. The dosage can vary depending on individual factors such as your medical condition and how you're responding to the medicine. It's crucial not to alter your dose without first consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Cordarone X Tablet, you might experience symptoms like a slower heart rate, disturbances in heart rhythm, and low blood pressure. Always take only the prescribed dose and reach out to your doctor if you suspect an overdose.

Missed Dose

If you forget to take a dose of Cordarone X Tablet, take it as soon as you remember. However, if it’s nearly time for your next dose, skip the missed dose and go back to your regular schedule. Don't increase your dose or take extra medicine to make up for a missed dose. Always consult your doctor for further guidance.

Store Cordarone X Tablet in a tight, light-resistant container.
Maintain the storage temperature between 20°C and 25°C.
Protect the medicine from direct light and moisture.
Keep this medicine out of the reach of children.
Always check the expiry date before use and discard if it has passed.

Limit your caffeine intake. Since Cordarone X Tablet is used to manage severe heart rhythm disorders, excessive caffeine can trigger irregular heartbeats.
Engage in light physical activity like walking or gentle yoga. Regular exercise can help maintain a healthy heart rhythm. However, do consult your doctor before starting any new exercise regime.

Fact Box

Drug Category	Class III Antiarrhythmic
Therapeutic Category	Heart Medication
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Ventricular Arrhythmias

What is Cordarone X Tablet used for?

It's used to manage serious, life-threatening ventricular arrhythmias when other medicines have failed or can't be tolerated.

How does Cordarone X Tablet work?

The active ingredient, amiodarone, prolongs heart cell action duration and inhibits certain nerve signals, helping prevent ventricular arrhythmias.

Can I take Cordarone X Tablet with food?

Yes, taking this medicine with food can enhance its absorption, making it more effective in managing arrhythmias.

What are some possible side effects of Cordarone X Tablet?

Side effects can include lung and liver issues, thyroid dysfunction, slow heartbeat, visual disturbances, and increased sensitivity to sunlight.

Can I stop taking Cordarone X Tablet abruptly?

No, you shouldn't stop taking this medicine without consulting your doctor as it may cause health issues.

Can Cordarone X Tablet interact with other medicines?

Yes, it can interact with many medicines including digoxin and warfarin. Always inform your doctor about all the medicines you're taking.

How should I store my Cordarone X Tablets?

Store at room temperature (20°C to 25°C), away from light and moisture in a tight container, out of children's reach.

Certified Content

Written by

Dr Vatsalya D Ghanekar

Medical Content Writer | 5 years

MD Ayurveda

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

References

Pfizer, Inc. (1985). CORDARONE. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/018972s054lbl.pdf
CORDARONE. (2021). AMIODARONE TABLETS I.P. CORDARONE [Pharmaceutical]. In CORDARONE (pp. 1–3). https://www.sanofi.in/dam/jcr:777ac12e-6472-46b5-9ebb-e2b12f85f989/Cordarone%C2%AE%20and%20Cordarone%C2%AE%20X%20Tablets%20--%20PI.pdf
DailyMed - AMIODARONE HYDROCHLORIDE tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=3e8db251-e3c5-4fba-be9a-6044a92f0beb
Amiodarone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01118
Florek, J. B., Lucas, A., & Girzadas, D. (2023, November 12). Amiodarone. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK482154/

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