Amitriptyline + Pregabalin

Dosage Forms Available

• Amitriptyline + Pregabalin is available as oral tablets and capsules. These are meant to be taken by mouth with water, as directed by the doctor.

• It is important to follow the instructions provided by the doctor for proper administration of this medication.

Age and Dose Restrictions

• This medicine is meant for adults and adolescents who are older than 16 years of age.

Contraindications

• Amitriptyline + Pregabalin is contraindicated in patients with known hypersensitivity to either of the active ingredients.

• It is also not recommended for individuals who have recently suffered a heart attack.

Other Medications to Avoid

• Amitriptyline + Pregabalin may interact with other antidepressants (such as fluoxetine and selegiline), anticonvulsants (like gabapentin and levetiracetam), and sedatives (including diazepam or lorazepam).

Overdose and Missed Dose

• If you accidentally take more than your prescribed dose of Amitriptyline + Pregabalin, you may experience symptoms such as severe drowsiness or confusion. In such cases, contact your doctor immediately or seek urgent medical attention.

• If you miss a dose of this medication, take it as soon as you remember. If it is already time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double up your dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and usually subside without intervention when this medication is discontinued. However, if you experience any severe side effects, please consult your doctor.

• Drinking plenty of water can help manage some of the common side effects, like dry mouth and constipation.

• If you experience confusion, taking your medication in the evening or before bedtime may be beneficial.

Use in Driving and Operating Machinery

• Amitriptyline + Pregabalin may cause drowsiness or dizziness. These side effects may affect your ability to drive or operate heavy machinery. It is advisable to avoid such activities until you know how this combination affects you.

Use in Pregnancy and Lactation

• Amitriptyline + Pregabalin should be used during pregnancy or breastfeeding only if the potential benefits outweigh the risks. Always consult your doctor before using this medication if you are pregnant or nursing.

Caution in Other Conditions

• Caution should be exercised when using Amitriptyline + Pregabalin in individuals with liver or kidney problems, diabetes, and certain psychiatric conditions.

• Individuals with a history of seizures or angle-closure glaucoma should also use this combination with caution.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet to help manage weight gain, a possible side effect of this medication.

• Regular but moderate physical activity can also aid in managing weight and improving overall well-being.

• For those experiencing constipation, a diet high in fibre combined with regular exercise can be beneficial.