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Amlodipine + Chlorthalidone

Uses of Amlodipine + Chlorthalidone

  • Amlodipine + Chlorthalidone is primarily used to manage high blood pressure. It belongs to a group of medicines known as calcium channel blockers and diuretics.

Side effects of Amlodipine + Chlorthalidone

  • Dizziness

  • Headache

  • Fatigue

  • Swelling of ankles and feet (Peripheral oedema)

  • Nausea

How Amlodipine + Chlorthalidone works

  • Amlodipine + Chlorthalidone is a combination medicine used to manage high blood pressure.

  • Amlodipine belongs to the group of medicines known as calcium channel blockers. It relaxes and widens your blood vessels by preventing calcium from entering muscle cells in the walls of your blood vessels. This causes your blood vessels to relax and widen, which decreases the resistance to blood flow and hence reduces your blood pressure.

  • Chlorthalidone is a diuretic, sometimes referred to as a 'water pill.' It helps your body get rid of extra water and salt by increasing urine output. This reduction in fluid volume also helps lower your blood pressure.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amlodipine + Chlorthalidone is available for use in the form of tablets.

Age and Dose Restrictions

  • This medicine is meant for use by adults only.

Contraindications

  • Amlodipine + Chlorthalidone is contraindicated in patients with severe kidney or liver impairment.

  • It is also contraindicated for those with a history of allergies to amlodipine, chlorthalidone, or other sulfonamide-derived medications.

  • Patients with gout should not use this medication due to its potential to raise uric acid levels.

Other Medications to Avoid

  • This combination may interact with NSAIDs (such as ibuprofen and naproxen), lithium, digoxin, bile acid sequestrants (like cholestyramine and colestipol), antifungals (such as ketoconazole), and antibiotics (like rifampin).

Overdose and Missed Dose

  • An overdose of Amlodipine + Chlorthalidone may result in marked hypotension, excessive peripheral vasodilation, electrolyte depletion, and dehydration. Immediate medical attention should be sought if an overdose is suspected.

  • If you miss a dose of this medicine, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening symptoms, please consult your doctor.

  • To manage dizziness or lightheadedness, try lying down until the sensations pass.

  • If experiencing peripheral oedema, elevating the feet can help reduce swelling.

Use in Driving and Operating Machinery

  • Amlodipine + Chlorthalidone may cause dizziness or fatigue, affecting your ability to drive or operate heavy machinery. Avoid engaging in such activities until you know how this medication affects you.

Use in Pregnancy and Lactation

  • Amlodipine + Chlorthalidone is not recommended during pregnancy or while breastfeeding due to potential risks to the baby. It is advised to consult a doctor if you are pregnant or planning to become pregnant while using this medicine.

Caution in Other Conditions

  • Caution is advised when using Amlodipine + Chlorthalidone in elderly patients as they may be more sensitive to its effects.

  • Patients with diabetes should monitor their blood sugar levels regularly while using this medicine, as it may affect glucose control.

Special Dietary and Lifestyle Recommendations

  • Reducing salt intake can be beneficial to support blood pressure management while using Amlodipine + Chlorthalidone.

  • Incorporating regular cardiovascular exercises like walking, jogging, or swimming into your routine can help maintain healthy blood pressure levels.

  • It is advisable to maintain a healthy weight to help manage hypertension effectively.

  • Avoiding excessive consumption of alcohol can also aid in controlling blood pressure.

  • Stress management techniques such as yoga, meditation, or deep breathing exercises can be beneficial in managing hypertension.

Frequently asked questions

Amlodipine + Chlorthalidone is primarily used to manage high blood pressure (hypertension). It is a combination medication which includes amlodipine, a calcium channel blocker, and chlorthalidone, a diuretic.

This medicine works by combining the effects of its two active ingredients. Amlodipine relaxes the blood vessels, while chlorthalidone helps reduce fluid buildup by promoting urine production. Together, they help to reduce high blood pressure.

No specific food items need to be avoided while taking this medicine. However, it is always recommended to maintain a healthy diet and lifestyle for the best results from any blood pressure medication.

While side effects vary among individuals, sleep disturbances are not commonly reported with Amlodipine + Chlorthalidone.

There are no known effects of Amlodipine + Chlorthalidone on fertility in either men or women.

No, this medicine should only be taken as per a doctor's instructions. Blood pressure management requires regular monitoring and dosage adjustments, which can only be done by a healthcare professional.

The time required for this medication to show its effect can vary among individuals. However, blood pressure changes are usually observed within a few hours to a few days of taking the medicine.

Terms & Conditions


Available medicines for AMLODIPINE + CHLORTHALIDONE
Enzochlor Tablet 10
Enzochlor Tablet 10
Druto Laboratories
Pack of 10 Units
₹75.33
MRP ₹91.86
18.00% OFF
Amlodac Ch Tablet 10
Amlodac Ch Tablet 10
Zydus Cadila
Pack of 10 Units
₹132.72
MRP ₹161.85
18.00% OFF
Amlong Ct Tablet 10
Amlong Ct Tablet 10
Micro Labs Ltd
Pack of 10 Units
₹53.30
MRP ₹65.00
18.00% OFF
Amlovas Ch 5/6.25 MG Tablet 10
Amlovas Ch 5/6.25 MG Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹47.56
MRP ₹58.00
18.00% OFF
Amlovas Ch 5/12.5 MG Tablet 10
Amlovas Ch 5/12.5 MG Tablet 10
Macleods Pharmaceuticals Pvt.ltd
Pack of 10 Units
₹56.58
MRP ₹69.00
18.00% OFF

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