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Amlodipine + Hydrochlorothiazide + Losartan

Uses of Amlodipine + Hydrochlorothiazide + Losartan

  • Amlodipine + Hydrochlorothiazide + Losartan is primarily used to manage high blood pressure. It belongs to the category of antihypertensive medicines.

Side effects of Amlodipine + Hydrochlorothiazide + Losartan

  • Fatigue

  • Dizziness

  • Nausea

  • Muscle cramps

  • Nasopharyngitis

How Amlodipine + Hydrochlorothiazide + Losartan works

  • Amlodipine, a calcium channel blocker, works by relaxing and widening the blood vessels. It does this by preventing calcium from entering muscle cells in the heart and blood vessel walls.

  • Hydrochlorothiazide is a type of water pill or diuretic. It removes extra water and certain electrolytes from the body through urine, helping to relax the blood vessels and decrease blood pressure.

  • Losartan is an angiotensin II receptor blocker (ARB). By blocking the action of a substance in the body that causes blood vessels to tighten, it helps blood vessels to relax and lower blood pressure. Together, these ingredients work in harmony to effectively manage high blood pressure.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amlodipine + Hydrochlorothiazide + Losartan is available for use via oral route in the form of tablets.

Age and Dose Restrictions

  • This medicine is meant for adults.

Contraindications

  • This combination is contraindicated in patients with anuria (inability to produce urine), severe liver impairment, refractory hypokalemia, hyponatremia, hypercalcemia and symptomatic hyperuricemia.

Other Medications to Avoid

  • This combination may interact with NSAIDs (such as ibuprofen and naproxen), diuretics (like furosemide and torsemide) and ACE inhibitors (including lisinopril and ramipril).

Overdose and Missed Dose

  • An overdose of Amlodipine + Hydrochlorothiazide + Losartan may result in severe hypotension, electrolyte disturbances, and stupor. If you observe these symptoms or any other unusual effects, inform your doctor immediately.

  • If you forget to take this medicine, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a forgotten one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • If you experience dizziness or lightheadedness after taking this medicine, sit or lie down until you feel better.

  • Staying well hydrated may help to reduce some side effects such as dry mouth and thirst.

Use in Driving and Operating Machinery

  • Amlodipine + Hydrochlorothiazide + Losartan may cause dizziness or fatigue. Avoid driving or operating heavy machinery if you feel dizzy or tired after taking this medicine.

Use in Pregnancy and Lactation

  • This medicine is contraindicated in the 2nd and 3rd trimesters of pregnancy.

  • Consult your doctor before using this medicine during breastfeeding.

Caution in Other Conditions

  • Patients with impaired kidney function, liver disease, hypokalemia (low potassium levels in the blood), hyponatremia (low sodium levels in the blood) and hypercalcemia (high calcium levels in the blood) should use this medicine with caution. Always discuss your medical history with your doctor before starting this medication.

Special Dietary and Lifestyle Recommendations

  • Reduce your intake of sodium (salt) and try to maintain a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and low-fat dairy products.

  • Try to keep active for at least 150 minutes a week. Regular exercise can help lower your blood pressure and keep it under control.

  • Try to maintain a healthy body weight. Being overweight can increase your blood pressure.

  • Try to reduce stress in your life as much as possible. High levels of stress can lead to temporary increases in blood pressure.

Frequently asked questions

No, Amlodipine + Hydrochlorothiazide + Losartan is not a steroid. This combination of medications is used to manage high blood pressure: Amlodipine is a calcium channel blocker, Hydrochlorothiazide is a diuretic, and Losartan is an angiotensin II receptor blocker (ARB).

Amlodipine + Hydrochlorothiazide + Losartan is not directly associated with affecting sleep disturbances. However, any changes in sleep patterns should be reported to your doctor.

Amlodipine + Hydrochlorothiazide + Losartan is not directly associated with affecting fertility in men or women. If you have concerns about fertility, it is recommended to consult your doctor.

It is safe to take Amlodipine + Hydrochlorothiazide + Losartan as prescribed by your doctor. It is formulated for daily use to control high blood pressure.

Amlodipine + Hydrochlorothiazide + Losartan starts working within a few hours of administration. However, it may take several weeks for you to notice the full benefit of the medicine.

The best time to take Amlodipine + Hydrochlorothiazide + Losartan is as directed by your doctor. It may be taken with or without food at the same time each day.

Abrupt discontinuation of this medicine might lead to a sudden increase in blood pressure levels. Always consult your doctor before stopping any medication.

Terms & Conditions


Amlodipine + Hydrochlorothiazide + Losartan in other salts

AMLODIPINEAMLODIPINE + HYDROCHLOROTHIAZIDE + TELMISARTANAMLODIPINE + METOPROLOLAMLODIPINE + OLMESARTAN MEDOXOMILAMLODIPINE + TELMISARTANS-AMLODIPINEHYDROCHLOROTHIAZIDE + TELMISARTANHYDROCHLOROTHIAZIDE + LOSARTANHYDROCHLOROTHIAZIDE + OLMESARTAN MEDOXOMILAMLODIPINE + ATENOLOLLOSARTANAMLODIPINE + RAMIPRILHYDROCHLOROTHIAZIDE + RAMIPRILAMLODIPINE + ENALAPRILLOSARTAN + RAMIPRILAMLODIPINE + METOPROLOL SUCCINATEAMLODIPINE + VALSARTANAMLODIPINE + ATORVASTATINAMLODIPINE + LISINOPRILAMLODIPINE + LOSARTANHYDROCHLOROTHIAZIDE + QUINAPRILAMLODIPINE + HYDROCHLOROTHIAZIDEAMILORIDE + HYDROCHLOROTHIAZIDEAMLODIPINE + INDAPAMIDEAMLODIPINE + CHLORTHALIDONEAMLODIPINE + NEBIVOLOL NEBIVOLOL + S-AMLODIPINEAMLODIPINE + PERINDOPRILATENOLOL + S-AMLODIPINEATENOLOL + LOSARTANHYDROCHLOROTHIAZIDEENALAPRIL + LOSARTANATORVASTATIN + S-AMLODIPINELOSARTAN + S-AMLODIPINES-AMLODIPINE + TELMISARTANHYDROCHLOROTHIAZIDE + S-AMLODIPINERAMIPRIL + S-AMLODIPINEATENOLOL + HYDROCHLOROTHIAZIDEHYDROCHLOROTHIAZIDE + METOPROLOL SUCCINATEBISOPROLOL + HYDROCHLOROTHIAZIDEHYDROCHLOROTHIAZIDE + METOPROLOLCHLORTHALIDONE + LOSARTANAMLODIPINE + BISOPROLOLHYDROCHLOROTHIAZIDE + VALSARTANHYDROCHLOROTHIAZIDE + IRBESARTANHYDROCHLOROTHIAZIDE + LOSARTAN + RAMIPRILENALAPRIL + HYDROCHLOROTHIAZIDEAMLODIPINE + CHLORTHALIDONE + TELMISARTANHYDROCHLOROTHIAZIDE + NEBIVOLOLS-AMLODIPINE + S-METOPROLOLAMLODIPINE + HYDROCHLOROTHIAZIDE + OLMESARTAN MEDOXOMILHYDROCHLOROTHIAZIDE + LISINOPRILATENOLOL + HYDROCHLOROTHIAZIDE + LOSARTANAMLODIPINE + CHLORTHALIDONE + OLMESARTAN MEDOXOMILHYDROCHLOROTHIAZIDE + RAMIPRIL + TELMISARTAN
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