Amlodipine + Lisinopril
Uses of Amlodipine + Lisinopril
The main use of Amlodipine + Lisinopril is the management of hypertension (high blood pressure). It falls under the category of antihypertensive medicines.
In addition to managing hypertension, it can also be prescribed for certain types of angina (chest pain), thereby helping prevent serious heart issues like heart attacks and strokes.
Side effects of Amlodipine + Lisinopril
Cough
Fatigue
Nausea
Headache
Dizziness
How Amlodipine + Lisinopril works
Amlodipine + Lisinopril is an antihypertensive combination.
Amlodipine is a calcium channel blocker. It works by relaxing and dilating the blood vessels. This occurs as it blocks calcium from entering vascular smooth muscle cells, which prevents constriction, allowing blood to flow more easily.
Lisinopril is an angiotensin-converting enzyme inhibitor. It works by blocking the enzyme that converts angiotensin I to angiotensin II. This results in dilated blood vessels, reduced aldosterone secretion, and suppressed renin-angiotensin-aldosterone system, thereby reducing blood pressure.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Amlodipine + Lisinopril is available for use via the oral route in the form of tablets.
Age and Dose Restrictions
Amlodipine + Lisinopril is suitable for adults and children above the age of 18 years.
Contraindications
This medicine is contraindicated in patients with known allergies to either amlodipine or lisinopril or any other ACE inhibitor.
Other Medications to Avoid
Amlodipine + Lisinopril may interact with potassium-sparing diuretics (such as spironolactone and triamterene) and NSAIDs (like ibuprofen and naproxen).
Overdose and Missed Dose
An overdose of Amlodipine + Lisinopril could cause symptoms such as low blood pressure, rapid heart rate, or even kidney failure. If you suspect an overdose, seek medical attention immediately.
If you miss a dose of Amlodipine + Lisinopril, take it as soon as you remember. However, if it is near the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, consult your doctor.
Most side effects like dizziness or headache can be managed by sitting or lying down until the symptoms pass.
Drinking plenty of water may help with minor side effects like dry mouth or thirst.
Use in Driving and Operating Machinery
Amlodipine + Lisinopril may cause dizziness or fatigue. If affected, avoid driving or operating heavy machinery until these symptoms pass.
Use in Pregnancy and Lactation
Amlodipine + Lisinopril is not recommended during pregnancy or breastfeeding. Always consult a doctor before using this medication if you are pregnant or breastfeeding.
Caution in Other Conditions
Patients with liver or kidney impairment should exercise caution when taking Amlodipine + Lisinopril as dose adjustment may be needed.
People on a low-salt diet or taking diuretics should also be cautious due to the increased risk of hypotension and kidney dysfunction.
Special Dietary and Lifestyle Recommendations
Maintain a low-sodium diet to help manage hypertension.
High levels of stress can contribute to high blood pressure. Practice stress management techniques such as deep breathing exercises and meditation.
Frequently asked questions
Can Amlodipine + Lisinopril cause sleep disturbances?
Amlodipine + Lisinopril is not typically associated with causing sleep disturbances. However, everyone reacts to medications differently. If you notice any changes in your sleep patterns, it is advisable to consult your doctor.
Will taking Amlodipine + Lisinopril affect my fertility?
Amlodipine + Lisinopril is not commonly associated with affecting fertility in men or women. However, if you have concerns about fertility, you should discuss them with your doctor.
Can the use of Amlodipine + Lisinopril result in weight gain?
Weight gain is not a typical side effect of Amlodipine + Lisinopril. However, each person's response to medication is unique, If you have concerns about weight change, it's important to discuss this with your doctor.
Does the effectiveness of Amlodipine + Lisinopril reduce over time?
The effectiveness of Amlodipine + Lisinopril should not diminish over time. If you feel that your medication is not working as well as it did initially, consult your doctor.
I have been prescribed Amlodipine + Lisinopril for hypertension; can I stop once my blood pressure is under control?
No, do not stop taking Amlodipine + Lisinopril without consulting your doctor. Stopping the medication abruptly can lead to a sudden increase in blood pressure, also known as rebound hypertension.
Are there any natural alternatives to Amlodipine + Lisinopril?
While certain lifestyle changes like a balanced diet, regular exercise, and stress management can help manage high blood pressure, they cannot replace the need for medication like Amlodipine + Lisinopril. Always consult your doctor before making any changes to your treatment regimen.
Can Amlodipine + Lisinopril be crushed or broken?
Amlodipine + Lisinopril is taken orally with or without food. Your doctor will decide on the appropriate dosage based on your blood pressure goals and response to the medication.
Amlodipine + Lisinopril in other salts
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