Amlodipine + Perindopril

Dosage Forms Available

• Amlodipine + Perindopril is available in tablet form for oral administration.

Age and Dose Restrictions

• Amlodipine + Perindopril is generally recommended for adults and children above 18 years of age.

Contraindications

• This medicine is contraindicated in patients with known hypersensitivity to perindopril, amlodipine, or any of the excipients.

• It is also contraindicated for patients with a history of angioedema related to previous ACE inhibitor therapy and patients with hereditary or idiopathic angioedema.

Other Medications to Avoid

• Amlodipine + Perindopril may interact with potassium supplements and potassium-sparing diuretics (eg., potassium chloride and spironolactone), non-steroidal anti-inflammatory medicines (eg., ibuprofen), and antidiabetic agents (eg., metformin).

Overdose and Missed Dose

• An overdose of Amlodipine + Perindopril may cause excessive peripheral vasodilation, marked and probably prolonged hypotension, shock, stupor, electrolyte disturbances, renal failure, hyperventilation, tachycardia, bradycardia, dizziness, anxiety, and cough. If you suspect an overdose, it is important to seek immediate medical attention.

• If you miss a dose of this medicine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water can help manage dizziness.

• Taking the medication with meals can help manage nausea or abdominal pain.

Use in Driving and Operating Machinery

• This medicine may affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness or fatigue after taking this medicine.

Use in Pregnancy and Lactation

• This medicine is not recommended during pregnancy and breastfeeding unless specifically advised by a healthcare professional due to the lack of specific data. Consult a doctor before taking this medicine during these periods.

Caution in Other Conditions

• Patients with renal impairment, aortic stenosis, hepatic impairment, hypovolemia, hyperkalemia, or collagen vascular diseases should exercise caution while taking Amlodipine + Perindopril.

Special Dietary and Lifestyle Recommendations

• Maintain a low-sodium diet to help control your blood pressure.

• Try to reduce stress through activities like meditation or yoga.