Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate is primarily used for the relief of cough due to minor throat and bronchial irritation, as well as for the symptomatic relief of allergic conditions. It belongs to the group of expectorants, antihistamines, and mucolytic agents.
Drowsiness
Dry mouth, nose, and throat
Dizziness
Nausea
Constipation
Ammonium chloride + chlorpheniramine maleate + sodium citrate is a combination medicine that belongs to the group of expectorant, antihistamine, and mucolytic properties.
Ammonium Chloride acts as an expectorant. It assists in drawing water into the airways, thinning mucus secretions, which in turn makes coughs more productive by irritating the mucous membranes.
Chlorpheniramine Maleate is an antihistamine. It helps with allergy symptoms by blocking a chemical in your body called histamine, which is responsible for causing a runny nose, watery eyes, itching, and sneezing. By stopping histamine, this medicine helps you feel more comfortable.
Sodium Citrate is a mucolytic agent. It helps by thinning and loosening mucus in your nose, throat, and lungs, making coughing easier. This helps to relieve coughing more effectively.
Doctor of Medicine
BMS, FMC, MD Resident
Dosage Forms Available
Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate is available as a liquid syrup formulation for oral administration.
Age and Dose Restrictions
This medication is meant for adults and children, but the dose for children depends on their age and weight. Advice from a doctor should be sought for child dosage.
Contraindications
This medicine is contraindicated in patients with known hypersensitivity to any of its active ingredients. It’s also not suitable for newborns, premature infants, or children under 2 years old. Additionally, it should not be used by nursing mothers, people taking monoamine oxidase inhibitors (MAOIs), or those with severe high blood pressure, coronary artery disease, peripheral vascular disease, or overactive thyroid.
Other Medications to Avoid
Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate can interact with monoamine oxidase inhibitors (such as phenelzine and tranylcypromine), CNS depressants (such as barbiturates and benzodiazepines), antihypertensives (like prazosin and losartan), anticoagulants (such as warfarin, heparin), antacids/anti-diarrheal medicines containing aluminium/magnesium (like Maalox and Pepto-Bismol), and potassium-depleting medicines (like prednisone and furosemide).
Overdose and Missed Dose
An overdose of this medicine may cause nausea, vomiting, excessive thirst, headache, rapid breathing, and increasing drowsiness. These can progress to serious conditions such as severe acidosis (an imbalance in the body's pH levels), low potassium levels in the blood, toxic psychosis, seizures, episodes of stopped breathing during sleep, involuntary muscle contractions, and cardiovascular issues like irregular heart rhythms and potential collapse. If you observe these symptoms, inform your doctor and follow their advice.
If you forget to take a dose of this medicine, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses to make up for the missed dose.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
To manage drowsiness or dizziness, avoid taking this medication during the day and take it before bedtime instead.
For dry mouth, try drinking plenty of water or sucking on ice chips.
Use in Driving and Operating Machinery
This medication may cause drowsiness, dizziness, or blurred vision. If you experience these side effects, avoid driving or operating heavy machinery until the effects subside.
Use in Pregnancy and Lactation
Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate should be used during pregnancy and lactation only if the potential benefits to the mother outweigh the potential risks to the fetus or infant. Always consult your doctor before using this medication while pregnant or breastfeeding.
Caution in Other Conditions
Caution is advised in patients with asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease, hypertension, and chronic lung diseases. Consult your doctor if you have these or other medical conditions before starting this medication.
Special Dietary and Lifestyle Recommendations
Drink plenty of fluids to help thin and loosen mucus.
Avoid allergens that may trigger symptoms like a runny nose, watery eyes, itching, and sneezing.
Maintain a healthy diet.
Frequently asked questions
No, this medication is only indicated for the relief of cough due to minor throat and bronchial irritation occurring with the common cold or inhaled irritants. It is not recommended for long-term use as it may cause dependence.
No, this combination does not contain steroids. It contains an expectorant (Ammonium Chloride), an antihistamine (Chlorpheniramine Maleate), and a mucolytic agent (Sodium Citrate).
Yes, this medicine provides relief from symptoms of allergic conditions such as seasonal allergies, hives, allergic conjunctivitis, and reactions to food or medications.
No, this combination is not specifically used for treating kidney stones. Sodium citrate may help prevent some types of stones by alkalizing the urine, but the other components do not address kidney stones directly.
Chlorpheniramine Maleate in the medicine can cause drowsiness or dizziness as one of its side effects.
This medication is not recommended for long-term use as it may cause dependence.
Take Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate in the evening or before bed, preferably after a meal to avoid drowsiness and stomach discomfort. If you have any specific concerns or conditions, consult your doctor.
Ammonium Chloride + Chlorpheniramine Maleate + Sodium Citrate in other salts
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