The main use of Amoxicillin + Cloxacillin is to manage various types of bacterial infections. This combination belongs to the group of antibiotics.
Additionally, it can manage respiratory tract infections like pneumonia and bronchitis, skin and soft tissue infections like cellulitis and boils, urinary tract and kidney infections, dental and oral infections, and bone and joint infections.
Nausea
Vomiting
Diarrhoea
Stomach pain
Skin rash
Amoxicillin + Cloxacillin is an antibiotic combination.
Amoxicillin works on bacteria by interfering with their cell wall synthesis. It binds to and inactivates penicillin-binding proteins (PBPs) located within the bacterial cell wall. These proteins are essential for cross-linking peptidoglycan chains that provide the cell wall with strength. When they are inhibited, the cell wall weakens, and the bacteria break down and die.
Cloxacillin also inhibits bacterial cell wall synthesis, but it also resists being broken down by the bacterial enzyme penicillinase. This makes it effective against some bacteria that are resistant to other penicillins.
BDS, MDS
BMS, FMC, MD Resident
Amoxicillin + Cloxacillin is available as tablets, capsules, and suspension for oral administration, and as injection to be administered via the intramuscular or intravenous route.
This medicine is intended for adults and children. The specific age appropriateness varies from newborns to the elderly depending on health conditions and individual dosage requirements.
This medicine is contraindicated in patients with known allergy to any penicillin or cephalosporin antibiotics and individuals who have a history of severe allergic reactions (anaphylaxis) to these antibiotics.
This combination may interact with oral contraceptives (such as ethinylestradiol and norgestrel), anticoagulants (like warfarin), antacids (such as aluminium hydroxide), iron supplements (like ferrous sulphate), and uricosurics (such as probenecid).
Symptoms of overdose include nausea, vomiting, diarrhoea, and kidney dysfunction. If you suspect an overdose, seek immediate medical attention.
If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double-dose to make up for a missed one.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.
For minor stomach upset or nausea, consider taking this medicine with food.
For diarrhoea, maintain hydration by drinking plenty of water.
Should a mild skin rash occur, reduce exposure to direct sunlight.
This medication may impair your alertness. If you experience dizziness or drowsiness after taking it, avoid driving or operating heavy machinery.
Amoxicillin + Cloxacillin falls under pregnancy category B. It is generally considered safe during pregnancy but should only be used under a doctor's supervision.
Although Amoxicillin is compatible with breastfeeding, Cloxacillin enters breast milk. If breastfeeding, monitor the infant for potential effects like diarrhoea or candidiasis and consult your doctor before use.
Caution is advised when using Amoxicillin + Cloxacillin in patients with kidney impairment and a history of gastrointestinal diseases related to antibiotic use, such as colitis.
Ensure adequate hydration to help mitigate potential renal issues from antibiotic therapy.
Consider incorporating probiotic-rich foods like yoghurt into your diet to support gut health during antibiotic treatment.
Maintain a balanced diet rich in fruits and vegetables to support overall health and recovery during infection management.
Regular hand washing and avoiding close contact with sick individuals can help prevent the spread of infections that might require antibiotic treatment.
Adequate rest is crucial for recovery when managing bacterial infections.
Frequently asked questions
Yes, it may reduce the effectiveness of oral contraceptives. Discuss with your doctor on the use of additional contraception while on this medicine.
Although not common, nervous system effects such as anxiety and confusion can occur. If you experience such symptoms, consult your doctor immediately.
It is usually recommended to avoid alcohol while taking this medication as it may increase the risk of side effects and can also interfere with the effectiveness of the medication.
No, you should continue the course as prescribed by your doctor, even if your symptoms improve.
No, it cannot be used to manage viral infections. It is an antibiotic medicine used to manage bacterial infections only.
No. The combination is an antibiotic medication made up of active ingredients that belong to the penicillin group of antibiotics.
You should continue with your regular balanced diet unless advised otherwise by your doctor.
Amoxicillin + Cloxacillin in other salts
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