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Amoxicillin + Cloxacillin

Uses of Amoxicillin + Cloxacillin

  • The main use of Amoxicillin + Cloxacillin is to manage various types of bacterial infections. This combination belongs to the group of antibiotics.

  • Additionally, it can manage respiratory tract infections like pneumonia and bronchitis, skin and soft tissue infections like cellulitis and boils, urinary tract and kidney infections, dental and oral infections, and bone and joint infections.

Side effects of Amoxicillin + Cloxacillin

  • Nausea

  • Vomiting

  • Diarrhoea

  • Stomach pain

  • Skin rash

How Amoxicillin + Cloxacillin works

  • Amoxicillin + Cloxacillin is an antibiotic combination.

  • Amoxicillin works on bacteria by interfering with their cell wall synthesis. It binds to and inactivates penicillin-binding proteins (PBPs) located within the bacterial cell wall. These proteins are essential for cross-linking peptidoglycan chains that provide the cell wall with strength. When they are inhibited, the cell wall weakens, and the bacteria break down and die.

  • Cloxacillin also inhibits bacterial cell wall synthesis, but it also resists being broken down by the bacterial enzyme penicillinase. This makes it effective against some bacteria that are resistant to other penicillins.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amoxicillin + Cloxacillin is available as tablets, capsules, and suspension for oral administration, and as injection to be administered via the intramuscular or intravenous route.

Age and Dose Restrictions

  • This medicine is intended for adults and children. The specific age appropriateness varies from newborns to the elderly depending on health conditions and individual dosage requirements.

Contraindications

  • This medicine is contraindicated in patients with known allergy to any penicillin or cephalosporin antibiotics and individuals who have a history of severe allergic reactions (anaphylaxis) to these antibiotics.

Other Medications to Avoid

  • This combination may interact with oral contraceptives (such as ethinylestradiol and norgestrel), anticoagulants (like warfarin), antacids (such as aluminium hydroxide), iron supplements (like ferrous sulphate), and uricosurics (such as probenecid).

Overdose and Missed Dose

  • Symptoms of overdose include nausea, vomiting, diarrhoea, and kidney dysfunction. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double-dose to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

  • For minor stomach upset or nausea, consider taking this medicine with food.

  • For diarrhoea, maintain hydration by drinking plenty of water.

  • Should a mild skin rash occur, reduce exposure to direct sunlight.

Use in Driving and Operating Machinery

  • This medication may impair your alertness. If you experience dizziness or drowsiness after taking it, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Amoxicillin + Cloxacillin falls under pregnancy category B. It is generally considered safe during pregnancy but should only be used under a doctor's supervision.

  • Although Amoxicillin is compatible with breastfeeding, Cloxacillin enters breast milk. If breastfeeding, monitor the infant for potential effects like diarrhoea or candidiasis and consult your doctor before use.

Caution in Other Conditions

  • Caution is advised when using Amoxicillin + Cloxacillin in patients with kidney impairment and a history of gastrointestinal diseases related to antibiotic use, such as colitis.

Special Dietary and Lifestyle Recommendations

  • Ensure adequate hydration to help mitigate potential renal issues from antibiotic therapy.

  • Consider incorporating probiotic-rich foods like yoghurt into your diet to support gut health during antibiotic treatment.

  • Maintain a balanced diet rich in fruits and vegetables to support overall health and recovery during infection management.

  • Regular hand washing and avoiding close contact with sick individuals can help prevent the spread of infections that might require antibiotic treatment.

  • Adequate rest is crucial for recovery when managing bacterial infections.

Frequently asked questions

Yes, it may reduce the effectiveness of oral contraceptives. Discuss with your doctor on the use of additional contraception while on this medicine.

Although not common, nervous system effects such as anxiety and confusion can occur. If you experience such symptoms, consult your doctor immediately.

It is usually recommended to avoid alcohol while taking this medication as it may increase the risk of side effects and can also interfere with the effectiveness of the medication.

No, you should continue the course as prescribed by your doctor, even if your symptoms improve.

No, it cannot be used to manage viral infections. It is an antibiotic medicine used to manage bacterial infections only.

No. The combination is an antibiotic medication made up of active ingredients that belong to the penicillin group of antibiotics.

You should continue with your regular balanced diet unless advised otherwise by your doctor.

Terms & Conditions


Available medicines for AMOXICILLIN + CLOXACILLIN
Emlox 500 MG Capsule 10
Emlox 500 MG Capsule 10
Zydus Cadila
Pack of 10 Units
₹21.52
MRP ₹26.25
18.00% OFF
Novaclox Nf Capsule 10
Novaclox Nf Capsule 10
Cipla Ltd.
Pack of 10 Units
₹56.93
MRP ₹94.38
39.68% OFF
Nodimox Plus 500 Capsule 10
Nodimox Plus 500 Capsule 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹50.02
MRP ₹61.00
18.00% OFF
Blumox Plus Capsule 15
Blumox Plus Capsule 15
Blue Cross Laboratories Ltd
Pack of 15 Units
₹70.93
MRP ₹86.50
18.00% OFF
Almox C 125/125mg Tablet 10
Almox C 125/125mg Tablet 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹18.45
MRP ₹22.50
18.00% OFF
Warclox 500/500 MG Capsule 9
Warclox 500/500 MG Capsule 9
Pfizer Ltd
Pack of 9 Units
₹21.30
MRP ₹25.98
18.00% OFF
Closomox Kid 125/125 MG Tablet 10
Closomox Kid 125/125 MG Tablet 10
Osho Pharma Pvt Ltd
Pack of 10 Units
₹9.02
MRP ₹11.00
18.00% OFF
Megaclox Capsule 10
Megaclox Capsule 10
Cipla Ltd.
Pack of 10 Units
₹57.66
MRP ₹115.55
50.10% OFF

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