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Amoxicillin + Sulbactam

Uses of Amoxicillin + Sulbactam

  • Amoxicillin + Sulbactam is primarily used for the management of various bacterial infections. It is part of the antibiotics group of medicines.

  • In addition to its primary use, it is also indicated for skin and skin structure infections, intra-abdominal infections, gynaecological infections, community-acquired pneumonia, hospital-acquired pneumonia, and bone and joint infections.

Side effects of Amoxicillin + Sulbactam

  • Diarrhoea

  • Nausea

  • Vomiting

  • Skin rash

  • Itching

How Amoxicillin + Sulbactam works

  • Amoxicillin + Sulbactam is a combination antimicrobial medicine.

  • Amoxicillin, a member of the penicillin family, works by inhibiting the synthesis of bacterial cell walls. This action disrupts the structure of harmful bacteria, preventing them from growing and multiplying.

  • Sulbactam is a beta-lactamase inhibitor. Some bacteria produce an enzyme called beta-lactamase that can break down penicillins like Amoxicillin, making them ineffective. Sulbactam blocks this enzyme, preserving the effectiveness of Amoxicillin and widening its spectrum of activity against different kinds of bacteria.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Amoxicillin + Sulbactam can be taken orally (tablet, dry syrup) and administered through the intramuscular or intravenous (injection) route.

Age and Dose Restrictions

  • This combination medicine is meant for adults as well as children. However, the specific dosage and method of administration would vary based on age, weight, and the specific condition being managed.

Contraindications

  • Use of Amoxicillin + Sulbactam is contraindicated in individuals with known severe hypersensitivity to penicillins, cephalosporins or other beta-lactams.

  • The medicine should also be avoided by patients who have a history of severe hepatic dysfunction or cholestatic jaundice associated with previous use of this combination.

Other Medications to Avoid

  • This combination may interact with uricosuric agents (such as probenecid) and xanthine oxidase inhibitors (such as allopurinol).

Overdose and Missed Dose

  • An overdose of Amoxicillin + Sulbactam might lead to symptoms of antibiotic-associated colitis, including persistent diarrhoea. If you accidentally take more than the prescribed dose, consult your doctor immediately.

  • In case you forget to take this medicine, take it as soon as you remember. However, if it is already time for your next dose, skip the missed one and continue with your regular schedule. Do not double dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience nausea or vomiting, try taking this medicine with food.

  • Drinking plenty of fluids can help manage diarrhoea.

  • For skin rash or itching, avoid hot showers as they can make itching worse. Use a moisturizing cream or lotion for relief.

Use in Driving and Operating Machinery

  • Amoxicillin + Sulbactam has no or negligible influence on the ability to drive and use machines. However, if you experience dizziness or any other side effects that may affect your concentration, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

  • Amoxicillin + Sulbactam should only be used during pregnancy or lactation if prescribed by your doctor.

Caution in Other Conditions

  • Patients with renal impairment should exercise caution when taking Amoxicillin + Sulbactam as dose adjustments may be required.

  • Also, patients with hepatic impairment should use this medicine with caution and under close medical supervision.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, whole grains, and lean proteins which can help strengthen the immune system.

  • Regularly engage in physical activities to keep the body active and healthy.

  • Avoid close contact with people who have infections to prevent the spread of bacteria.

  • Regular hand washing is recommended to prevent bacterial infections.

Frequently asked questions

No, Amoxicillin + Sulbactam is not a steroid. It is an antibiotic, specifically a combination of a penicillin-type antibiotic and a beta-lactamase inhibitor.

Amoxicillin + Sulbactam is not directly associated with affecting sleep. However, if you experience sleep disturbances after taking this medicine, consult your doctor.

Amoxicillin + Sulbactam is not associated with affecting fertility. If you have concerns about this, consult your doctor before taking this medicine.

Yes, it is safe to take Amoxicillin + Sulbactam daily as long as it is prescribed by your doctor. Do not exceed the recommended dose and duration of treatment.

After oral administration, Amoxicillin and Sulbactam are rapidly absorbed from the gastrointestinal tract, with peak levels reached within 1-2 hours and 30-60 minutes respectively, indicating that the medicine starts working soon after intake.

The best time to take this medicine would be as directed by your doctor. The research data indicates that food does not interfere with the absorption of Amoxicillin + Sulbactam, which means it can be taken with or without meals.

Amoxicillin + Sulbactam is not directly associated with affecting menstruation. However, if you have concerns, consult your doctor for personalized advice.

Terms & Conditions


Available medicines for AMOXICILLIN + SULBACTAM
Amphy Ibl 500/500 MG Tablet 10
Amphy Ibl 500/500 MG Tablet 10
Profic Organics
Pack of 10 Units
₹442.80
MRP ₹540.00
18.00% OFF
Amphy Ibl 250/250 MG Dry Syrup 30 ML
Amphy Ibl 250/250 MG Dry Syrup 30 ML
Profic Organics
Pack of 30 ML
₹134.48
MRP ₹164.00
18.00% OFF
Amphy 250/125 MG Injection 5 ML
Amphy 250/125 MG Injection 5 ML
Profic Organics
Pack of 5 ML
₹46.33
MRP ₹56.50
18.00% OFF
Amphyibl 750/250 MG Tablet 10
Amphyibl 750/250 MG Tablet 10
Profic Organics
Pack of 10 Units
₹381.30
MRP ₹465.00
18.00% OFF
Synbeta 500/500 MG Tablet 10
Synbeta 500/500 MG Tablet 10
Alniche Life Sciences Pvt.ltd
Pack of 10 Units
₹340.30
MRP ₹415.00
18.00% OFF
Amphy 1000/50 MG Injection 10 ML
Amphy 1000/50 MG Injection 10 ML
Profic Organics
Pack of 10 ML
₹170.56
MRP ₹208.00
18.00% OFF
Amphy Ibl 500 MG Tablet 10
Amphy Ibl 500 MG Tablet 10
Profic Organics
Pack of 10 Units
₹287.00
MRP ₹350.00
18.00% OFF
Aggreso 1000 MG Tablet 10
Aggreso 1000 MG Tablet 10
Innokon Laboratories Pvt Ltd
Pack of 10 Units
₹639.60
MRP ₹780.00
18.00% OFF

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