Ampicillin + Sulbactam

Dosage Forms Available

• Ampicillin + Sulbactam is administered via the intravenous or intramuscular route (powder for reconstitution).

Age and Dose Restrictions

• This combination medicine is recommended for use in both adults and paediatric patients aged one year and older.

Contraindications

• This medicine should not be administered to those who have severe hypersensitivity to any penicillin, cephalosporin, or beta-lactam antibiotic. It is also contraindicated in those who have had a history of cholestatic jaundice or hepatic dysfunction due to prior use of Ampicillin + Sulbactam. It is not used in pediatric patients for intra-abdominal infections.

Other Medications to Avoid

• Ampicillin + Sulbactam Ampicillin and Sulbactam may interact with other antibiotics (such as erythromycin), anticoagulants (like warfarin, heparin), and diuretics (such as furosemide, aminoglycosides). Additionally, it may interact with gout medications (probenecid and allopurinol), which can impact the effectiveness and safety of the treatment.

Overdose and Missed Dose

• Overdose of Ampicillin + Sulbactam may lead to an increased risk of side effects and complications such as neurological adverse effects like convulsions can occur. If you think you have taken too much of this medicine, consult your doctor immediately.

• If you miss a dose, take it as soon as you remember. But if it is close to your next dose, then skip the missed one and continue with your regular schedule. Do not double the dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Staying hydrated may help manage side effects like diarrhoea and nausea.

• Resting and relaxing may help alleviate headaches and dizziness.

Use in Driving and Operating Machinery

• Ampicillin + Sulbactam may cause side effects such as dizziness. If you experience these side effects, it is advisable to avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• This combination is classified as Pregnancy Category B. It should only be used during pregnancy and lactation if clearly needed and recommended by a doctor.

Caution in Other Conditions

• Patients with impaired renal function may need to have their dosage adjusted, as both ampicillin and sulbactam are primarily eliminated unchanged in the urine.

Special Dietary and Lifestyle Recommendations

• For managing bacterial infections, it's important to maintain good personal hygiene.

• Adequate rest may also help your body fight off infections more effectively.