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Anti Rh-d Immunoglobulin

Uses of Anti Rh-d Immunoglobulin

  • The primary use of Anti Rh-D Immunoglobulin is to manage conditions related to the Rhesus D (Rh D) antigen, particularly in preventing the sensitisation of Rh-negative pregnant women to the antigen. It falls under the category of immune globulins.

  • Aside from its main use, it may also be given following events like miscarriage, abortion, and ectopic pregnancy or after procedures like amniocentesis, which could potentially allow foetal blood to enter maternal circulation.

Side effects of Anti Rh-d Immunoglobulin

  • Pain and tenderness at the injection site

  • Mild fever

  • Headache

  • Dizziness

  • Malaise

How Anti Rh-d Immunoglobulin works

  • Anti Rh-D Immunoglobulin belongs to the category of medications known as immunoglobulins.

  • It contains antibodies that specifically target and neutralise the Rh-D antigen on red blood cells. In this way, it prevents the mother's immune system from producing its own harmful anti-D antibodies. The anti-D antibodies in Anti Rh-D Immunoglobulin work by binding to Rh-positive foetal red blood cells that may have entered the mother's bloodstream during pregnancy or childbirth.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama Ahmed Dental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Anti Rh-D Immunoglobulin is available as an injection intended for intramuscular administration.

Age and Dose Restrictions

  • This medicine is specifically designed for use in adult women, particularly those who are pregnant.

Contraindications

  • Anti Rh-D Immunoglobulin is contraindicated in Rh-positive women. It is also contraindicated in Rh-negative women who are already sensitised to the Rh-D antigen.

Other Medications to Avoid

  • This medicine may interact with live virus vaccines (such as measles, mumps, and rubella). It is recommended that such vaccines be administered at least three months before or after the administration of Anti Rh-D Immunoglobulin.

Overdose and Missed Dose

  • Overdose of Anti Rh-D Immunoglobulin may lead to increased severity of side effects such as fever or pain at the injection site. In such cases, it is advisable to consult a doctor immediately.

  • If a dose is missed during the prescribed time frame after childbirth or a sensitising event, it should be administered as soon as possible.

Management of Side Effects


Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • To manage mild fever or headache, resting and staying hydrated may help relieve symptoms.

  • If experiencing pain or tenderness at the injection site, applying a cold pack may reduce discomfort.

Use in Driving and Operating Machinery

  • Anti Rh-D Immunoglobulin does not impair the ability to drive or operate heavy machinery. However, if you experience dizziness or malaise after receiving the injection, it is advisable to avoid such activities until these feelings subside.

Use in Pregnancy and Lactation

  • Anti-Rh-D Immunoglobulin is specifically used during pregnancy to prevent haemolytic disease of the newborn. It is safe for pregnant women when administered as directed but should be used under medical supervision. However, please consult a doctor before taking this medicine if you are breastfeeding.

Caution in Other Conditions

  • Caution is advised in women with bleeding disorders or thrombocytopenia when using Anti Rh-D Immunoglobulin. There are no specific contraindications related to other conditions, but individual health circumstances should always be discussed with a doctor prior to administration.

Special Dietary and Lifestyle Recommendations

  • While Anti Rh-D Immunoglobulin itself does not require specific dietary changes, maintaining overall good health during pregnancy can benefit both mother and baby.

  • Consuming a balanced diet rich in iron can help manage and prevent anaemia, often a concern during pregnancy.

  • Staying adequately hydrated and engaging in moderate exercise, as recommended by a doctor, can also support overall health during pregnancy.

  • It is important to attend all prenatal appointments and discuss any concerns regarding medications or health conditions with a healthcare provider.

Frequently asked questions

No, Anti Rh-D Immunoglobulin is not a steroid. It is a type of medication used to manage conditions related to Rh incompatibility.

There is no evidence or reported side effect suggesting that Anti Rh-D Immunoglobulin affects sleep.

Anti Rh-D Immunoglobulin is not known to affect fertility. It is used to manage potential complications in pregnancy related to Rh incompatibility.

There are no specific diet restrictions associated with the use of Anti Rh-D Immunoglobulin.

Anti Rh-D Immunoglobulin is typically not taken daily but administered at certain times during pregnancy, post-childbirth, or after certain events. It should always be used according to the doctor's instructions.

The effectiveness of Anti Rh-D Immunoglobulin varies from person to person based on individual physiological factors. Speak with your doctor for more information.

Anti Rh-D Immunoglobulin is usually administered at particular times during pregnancy or post childbirth, rather than at a specific time of day. Its administration should always be under the supervision of a doctor.

Terms & Conditions

Available medicines for ANTI RH-D IMMUNOGLOBULIN
Rhogam Uf 300 MCG Injection 1 ML
Rhogam Uf 300 MCG Injection 1 ML
Johnson & Johnson
Pack of 1 ML
₹2101.25
MRP ₹2562.50
18.00% OFF
Antid 150mcg Injection 1ml
Antid 150mcg Injection 1ml
Bharat Serums & Vaccines Ltd
Pack of 1 ML
₹2398.50
MRP ₹2925.00
18.00% OFF
Antid 300mcg Injection 1ml
Antid 300mcg Injection 1ml
Bharat Serums & Vaccines Ltd
Pack of 1 ML
₹3553.76
MRP ₹4333.85
18.00% OFF
Immuno Rho 300 MCG Injection 1
Immuno Rho 300 MCG Injection 1
United Biotech (p) Ltd
Pack of 1 Units
₹1353.00
MRP ₹1650.00
18.00% OFF
Rhoclone 300 MCG Injection 1
Rhoclone 300 MCG Injection 1
Bharat Serums & Vaccines Ltd
Pack of 1 UNIT
₹1964.84
MRP ₹2396.15
18.00% OFF
Rhoclone 150mcg Injection 1ml
Rhoclone 150mcg Injection 1ml
Bharat Serums & Vaccines Ltd
Pack of 1 ML
₹1696.61
MRP ₹2069.04
18.00% OFF
Rhogam 300 MCG Injection 15 ML
Rhogam 300 MCG Injection 15 ML
Johnson & Johnson
Pack of 15 ML
₹2000.72
MRP ₹2439.90
18.00% OFF

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