Antid 300 Mcg Injection 1

Antid 300mcg Injection 1ml

Bharat Serums & Vaccines Ltd

Vial of 1 ML

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MRP ~~₹4333.85~~

₹3553.76

₹4333.85/ML

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Composition

Anti Rh-d Immunoglobulin (300 Mcg)

AntiD 300 mcg / 1ml liquid Injection falls under the category of medications known as 'immunising agents' prescribed to prevent rhesus disease. This injection is made with a particular immune system protein. It helps prevent a condition called hemolytic disease of the newborn (HDN) when there's a mismatch in blood types between the mother and baby.

During pregnancy, some women have a different blood type than their babies. This can lead to a risk of the mother's immune system attacking the baby's red blood cells, causing HDN. To avoid this problem, doctors give AntiD 300 mcg / 1ml liquid Injection to Rh-negative pregnant women at specific times during their pregnancy and after giving birth.

Before receiving an AntiD 300 mcg / 1ml liquid Injection, please let your doctor know if you've had a recent vaccination within the past 2 to 4 weeks, have any blood clotting issues, or suffer from thrombocytopenia (a reduced platelet count in your blood).

The uses of AntiD 300 mcg / 1ml liquid Injection are:

Prevents hemolytic disease of the newborn (HDN): The primary use of AntiD 300 mcg / 1ml liquid Injection is to prevent HDN in cases of Rh incompatibility between the mother and baby's blood types.
Postpartum administration: In addition to prenatal use, AntiD 300 mcg / 1ml liquid Injection may also be given to Rh-negative women after childbirth to prevent any potential issues in future pregnancies.

Directions for Use of Antid 300mcg Injection 1ml

Please remember that your healthcare professional should only administer this medicine. Do not attempt to self-administer it.

The AntiD 300 mcg / 1ml liquid Injection is administered intramuscularly (IM), which means it is injected into a muscle.

Side Effects of Antid 300mcg Injection 1ml

Common side effects of the AntiD 300 mcg / 1ml liquid Injection are as follows.

Injection site tenderness and pain
Fever
Headache
A feeling of discomfort

Managing the Side Effects:

Here’s how you can manage the side effects of the AntiD 300 mcg / 1ml liquid Injection

Injection site tenderness and pain: Apply a cold compress to the injection site to reduce discomfort. Avoid excessive movement or pressure on the area. If the tenderness persists or worsens, consult your doctor.
Fever: Rest and stay hydrated. You can take over-the-counter fever-reducing medications (if your doctor advises) to manage the fever. If the fever persists or becomes severe, seek medical attention.
Headache: Get plenty of rest and stay well-hydrated. Over-the-counter pain relievers, like (if safe for you) may help alleviate the headache. If the headache persists or worsens, consult your doctor.
A feeling of discomfort: Engage in relaxation techniques, such as deep breathing or meditation, to ease the discomfort. Maintain a comfortable environment and get adequate rest. If discomfort persists or becomes bothersome, seek guidance from your doctor.

The AntiD 300 mcg / 1ml liquid Injection contains a particular protein called recombinant Anti Rho-D immunoglobulin.
When injected into the mother's body, this protein helps stop the mother's immune system from attacking the baby's blood cells. It acts like a shield, protecting the baby's red blood cells from harm.
By doing this, the AntiD 300 mcg / 1ml liquid Injection ensures that the baby's blood cells remain healthy and intact.

Pregnancy

AntiD 300 mcg / 1ml liquid Injection is safe during pregnancy, and it is often prescribed to prevent HDN in cases of Rh incompatibility. However, always consult with your doctor before taking any medication during pregnancy.

Breastfeeding

There are no known harmful effects on breastfeeding infants when using AntiD 300 mcg / 1ml liquid Injection. It is safe for breastfeeding mothers, but it is advisable to consult your doctor before administering the injection while breastfeeding.

Alcohol

There are no known interactions between AntiD 300 mcg / 1ml liquid Injection and alcohol. However, it is generally recommended to avoid alcohol consumption during pregnancy for the overall well-being of both mother and baby.

Liver

AntiD 300 mcg / 1ml liquid Injection is generally considered safe for patients with liver diseases. However, your doctor will carefully evaluate the benefits and possible risks before prescribing them.

Kidney

It is likely safe to use AntiD 300 mcg / 1ml liquid Injection for patients with kidney diseases. However, your doctor will thoroughly assess the benefits and risks to ensure your safety.

Using Machines & Driving

AntiD 300 mcg / 1ml liquid Injection is not known to cause drowsiness or affect the ability to operate machinery or drive.

Allergy

Inform your doctor if you have allergies or hypersensitivity to immunoglobulin products or other components of AntiD 300 mcg / 1ml liquid Injection.

Interactions of Antid 300mcg Injection 1ml

Drug-Drug Interactions

AntiD 300 mcg / 1ml liquid Injection may interact with the following vaccines. It may transiently impair the efficacy of these live attenuated virus vaccines.

Varicella (live attenuated)
Measles, Mumps, and Rubella (MMR) vaccine

Drug-Disease Interactions

AntiD 300 mcg / 1ml liquid Injection can interact with conditions/diseases, including

Clotting disorders
Thrombocytopenia (decrease in number of platelets)

Daily Dose

The standard dosage intervals are usually around 28 to 30 weeks of gestation for Rh-negative pregnant women and within 72 hours after giving birth. AntiD 300 mcg /1ml liquid Injection dosage intervals may vary depending on individual medical circumstances and recommendations by doctors. AntiD 300 mcg / 1ml liquid Injections are generally administered at specific points during pregnancy and postpartum.

Over Dose

There are limited reports of overdose since trained professionals administer AntiD 300 mcg / 1ml liquid Injection. The specific symptoms of an overdose are not well-defined. If an overdose occurs, close patient monitoring is necessary, as there may be a risk of hemolysis, a condition where red blood cells break down.

Missed Dose

If you miss a dose of this injection, promptly schedule another appointment with your doctor. Inform the doctor about the missed dose during the appointment. It's essential to follow your doctor's instructions regarding the dosage to ensure the best possible outcome of the treatment.

The storage instructions for AntiD 300 mcg / 1ml liquid Injection are as follows:

Store the injection in a cool and dry place, away from direct sunlight.
Keep it in a refrigerator (2 - 8°C).
Do not freeze the injection to maintain its efficacy.
Follow any specific storage instructions your doctor provides or on the product label.

Follow your doctor's recommendations and undergo blood tests during pregnancy to determine your Rh factor (Rh-positive or negative).
Maintain a healthy diet to support your well-being and your baby's development.
Refrain from consuming alcohol and quit smoking during pregnancy to avoid potential complications.
Adhere to your doctor's prescription and take your medications regularly for a safe and healthy pregnancy.

Fact Box

Drug Category	Immunoglobulin preparation
Therapeutic Category	Haematological agent
Available Dosage Types	Injectable solution
Habit Forming	No
Ailment	Prevention of hemolytic disease of the newborn (HDN) in cases of Rh

Why is AntiD 300 mcg / 1ml liquid Injection given?

AntiD 300 mcg / 1ml is usually given to Rh-negative pregnant women to prevent hemolytic disease of the newborn (HDN) in cases of Rh incompatibility. It may also be administered after specific pregnancy-related procedures or complications.

Can AntiD 300 mcg / 1ml liquid Injection prevent miscarriage?

AntiD 300 mcg / 1ml is not explicitly used to prevent miscarriage. It is primarily given to prevent HDN in cases of Rh incompatibility during pregnancy.

Is AntiD 300 mcg / 1ml liquid Injection given in every pregnancy?

No, AntiD 300 mcg / 1ml injection is typically given to Rh-negative pregnant women during specific points in their pregnancy and postpartum to prevent HDN. Its administration depends on the individual's Rh status and other factors the doctor determines.

Does AntiD 300 mcg / 1ml liquid Injection affect the baby?

No, AntiD 300 mcg / 1ml is given to protect the baby from the potential consequences of Rh incompatibility, not to harm the baby. It helps prevent HDN, a condition that can lead to serious health issues for the baby.

How long does the effect of AntiD 300 mcg / 1ml liquid Injection last?

The effect of AntiD 300 mcg / 1ml injection lasts for a specific period, usually until the next administration is due, as prescribed by the doctor.

What happens if I miss my appointment of AntiD 300 mcg / 1ml liquid Injection?

If you miss your scheduled appointment for an AntiD 300 mcg / 1ml injection, it is essential to inform your doctor. They will guide you on the appropriate action and may reschedule the administration to ensure optimal protection against HDN.

Is the AntiD 300 mcg / 1ml liquid Injection painful?

The experience of pain during the injection may vary from person to person. However, healthcare professionals are trained to administer injections with minimal discomfort. If you have concerns about pain or discomfort, you can discuss them with your doctor.

Last Updated On 21 Nov. 2023 | 6:20AM (IST)

Certified Content

Written by

Dr. Nikhil Ambatkar

Clinical Health & Medical Writer | 6 years

Ph.D, M.Tech, B.Tech

Reviewed by

Dr. Betina Chandolia

Medical Content Manager | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

17TH FLOOR, HOECHST HOUSE NARIMAN POINT MUMBAI MH 400021 IN

Country of origin: INDIA

References

Rhophylac Rh (d) immune globulin intravenous (human) 0. (n.d.-c). https://www.fda.gov/media/75013/download
Package leaflet: Information for the user_Rhophylac®. (n.d.). Retrieved November 9, 2023, from https://www.medicines.org.uk/emc/files/pil.6791.pdf
NHS. (n.d.). NHS choices. https://www.nhs.uk/conditions/rhesus-disease/prevention/
National Institutes of Health. (n.d.). DailyMed - Rhophylac (human rho- D immune globulin solution. U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c1b5d801-336f-4541-a7d9-a8d4a110a4cc
About Rhophylac®. Rhophylac, Rho(D), Immune Globulin Intravenous (Human). (n.d.). https://www.rhophylac.com/about/about-rhophylac.aspx
Rhogam, Gamulin Rh (rho(d) immune globulin) dosing, indications, interactions, adverse effects, and more [Internet]. 2023 [cited 2023 Jul 20]. Available from: https://reference.medscape.com/drug/rhogam-hyperrho-s-d-rho-d-immune-globulin-343143

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