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Benzalkonium Chloride + Bromfenac

Uses of Benzalkonium Chloride + Bromfenac

  • The primary use of Benzalkonium Chloride + Bromfenac is in managing postoperative inflammation and pain following cataract surgery. This combination belongs to the group of nonsteroidal anti-inflammatory medicines (NSAIDs) and antimicrobial preservatives.

  • It is also used in various ophthalmic solutions due to its dual role: Benzalkonium chloride serves as a preservative to maintain the sterility of the product and prevent microbial growth, while bromfenac has anti-inflammatory and analgesic effects.

Side effects of Benzalkonium Chloride + Bromfenac

  • Eye irritation

  • Stinging sensation

  • Corneal damage

  • Allergic reactions

  • Minor ocular discomfort

How Benzalkonium Chloride + Bromfenac works

  • Benzalkonium Chloride + Bromfenac is an antimicrobial and anti-inflammatory combination.

  • Benzalkonium Chloride is an antimicrobial preservative. It works by disrupting the cell membranes of harmful microorganisms, causing leakage of their contents and leading to their death. This action helps to maintain the sterility of the ophthalmic solution and prevents microbial growth.

  • Bromfenac is a nonsteroidal anti-inflammatory medicine. It works by inhibiting the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. These enzymes are responsible for making prostaglandins, which contribute to inflammation and pain. By inhibiting these enzymes, Bromfenac reduces the production of prostaglandins, thereby reducing inflammation and pain in the eye.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Bromfenac is administered topically to the eyes (eye drops).

Age and Dose Restrictions

  • This combination of Benzalkonium Chloride + Bromfenac is meant for use in adults and children above 12 years of age.

Contraindications

  • This medicine is contraindicated in patients with known allergies to bromfenac, benzalkonium chloride, or any other ingredients in the formulation. It is also contraindicated in patients with active ocular infections and known bleeding disorders.

Other Medications to Avoid

  • Benzalkonium Chloride + Bromfenac cmay interact with other ocular medications, including additional nonsteroidal anti-inflammatory eye drops (like ketorolac), other eye drops containing preservatives (such as thimerosal), and other corticosteroid eye drops (like prednisolone).

Overdose and Missed Dose

  • In case you happen to put a few extra drops of this medicine in your eye, do not panic. Rinse your eyes with clean water at room temperature. If any symptoms persist or worsen, inform your doctor.

  • If you miss a dose, administer it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If stinging or burning is bothersome, gently flush your eyes with clean, lukewarm water to alleviate discomfort.

  • Use sunglasses to protect your eyes from bright light and glare, especially when outdoors or in bright environments.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Bromfenac may cause temporary blurring of vision. Patients should avoid driving or operating heavy machinery until their vision is clear.

Use in Pregnancy and Lactation

  • Pregnant or breastfeeding women should consult their doctor before using Benzalkonium Chloride + Bromfenac.

Caution in Other Conditions

  • Patients with known allergies to NSAIDs should exercise caution when using Benzalkonium Chloride + Bromfenac.

  • Individuals with a history of bleeding disorders should also be cautious while using this medicine.

Special Dietary and Lifestyle Recommendations

  • Regular eye check-ups can help monitor your eye health and detect any potential complications early.

  • Avoid direct exposure to heat, dust, and pollution as they can increase eye irritation.

  • Protect your eyes from harmful ultraviolet rays by wearing sunglasses when outside in bright sunlight.

  • Ensure good hygiene while handling the eye dropper to prevent contamination.

Frequently asked questions

While Benzalkonium Chloride + Bromfenac is primarily used in managing postoperative eye inflammation and pain, it does not causes any significant changes in mood.

Yes, Benzalkonium Chloride + Bromfenac can be used by those following a vegetarian or vegan diet. The medicine does not contain any animal-derived ingredients.

While some natural remedies may help soothe irritated or slightly inflamed eyes, they are not proven alternatives to this combination, especially for managing postoperative inflammation and pain. It is advised to consult your doctor before trying any substitutes.

The exact half-life of the combination is not specified, but it typically depends on multiple factors, including the individual's age, health condition, and the specific dosage used.

Benzalkonium Chloride + Bromfenac is not known to cause addiction or dependency as it does not contain any addictive substances.

In general, taking this medicine should not have any effect on menstruation. However, if you notice any irregularities or have concerns, do consult your doctor.

Benzalkonium Chloride + Bromfenac is not associated with having any considerable impact on appetite. If you experience any unusual symptoms while using this medicine, consult your doctor.

Terms & Conditions


Benzalkonium Chloride + Bromfenac in other salts

BENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINBROMFENACBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBENZALKONIUM CHLORIDE + GANCYCLOVIR
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