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Benzalkonium Chloride + Fluorometholone + Tobramycin

Uses of Benzalkonium Chloride + Fluorometholone + Tobramycin

  • The primary use of Benzalkonium Chloride + Fluorometholone + Tobramycin is to manage bacterial eye infections and related inflammation. This combination belongs to the class of antimicrobial, corticosteroid, and aminoglycoside medications.

  • This medication is also indicated for managing inflammations of the palpebral and bulbar conjunctiva, cornea, and anterior eye segment, as well as corticosteroid-responsive inflammatory eye conditions.

Side effects of Benzalkonium Chloride + Fluorometholone + Tobramycin

  • Eye irritation

  • Stinging in the eyes

  • Elevated intraocular pressure

  • Glaucoma

  • Cataracts

How Benzalkonium Chloride + Fluorometholone + Tobramycin works

  • Benzalkonium Chloride acts as an antimicrobial agent. Being a quaternary ammonium compound, it disrupts the cell membranes of bacteria, causing leakage of their contents and ultimately, their death.

  • Fluorometholone is a corticosteroid that reduces inflammation in the eyes. It achieves this by inhibiting actions such as swelling (edema), formation of fibrous tissue (fibrin deposition), widening of blood vessels (capillary dilation), and migration of immune cells (phagocytic migration).

  • Tobramycin is an antibiotic belonging to the aminoglycoside group. It stops bacterial growth by sticking to a part of the bacteria called the 30S ribosomal subunit, disrupting protein formation. This method specifically works against many types of gram-negative bacteria.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Benzalkonium Chloride + Fluorometholone + Tobramycin is available as an ophthalmic suspension or eye drops, which are meant for ocular or topical application on the eyes.

Age and Dose Restrictions

  • This combination medicine is generally intended for use in adults and children who are 2 years of age and older.

Contraindications

  • The use of this medicine is contraindicated in patients with known hypersensitivity reactions to benzalkonium chloride, fluorometholone or tobramycin.

  • It is also not recommended for patients with viral diseases of the cornea and conjunctiva like herpes simplex keratitis, vaccinia or varicella.

  • Patients with Mycobacterial or fungal infections of the eye should also avoid this medication.

Other Medications to Avoid

  • This combination may interact with nonsteroidal anti-inflammatory medicines (like ibuprofen and naproxen), other aminoglycosides (such as amikacin) and loop diuretics (like furosemide).

Overdose and Missed Dose

  • Overdosing on Benzalkonium Chloride + Fluorometholone + Tobramycin could lead to an increase in side effects such as eye irritation, blurred vision or increased intraocular pressure. If you suspect an overdose, consult your doctor immediately.

  • In case you miss a dose, apply it as soon as you remember. However, if it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not double up on doses.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If the medicine causes eye irritation or discomfort, resting your eyes can help.

  • Be sure to wash your eyes with clean water if you experience an increase in redness or itchiness.

  • If you feel a stinging sensation upon application, wait for it to subside. But if it persists, inform your doctor.

Use in Driving and Operating Machinery

  • Benzalkonium Chloride + Fluorometholone + Tobramycin may cause temporary blurred vision after application. Therefore, it is advised not to drive or operate heavy machinery until your vision is clear.

Use in Pregnancy and Lactation

  • It is advised to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution should be exercised in patients with glaucoma, corneal thinning, or compromised corneal integrity as Benzalkonium Chloride + Fluorometholone + Tobramycin may exacerbate these conditions.

Special Dietary and Lifestyle Recommendations

  • Maintain good eye hygiene to avoid further infection.

  • Avoid touching or rubbing your eyes to prevent the spread of infection.

  • Wear sunglasses to protect your eyes from harmful UV rays which can exacerbate eye inflammation.

  • Stay hydrated to keep your eyes moist and comfortable.

  • Include foods rich in Vitamin A and Vitamin C in your diet to support eye health.

Frequently asked questions

You may notice an improvement in your symptoms after a few days, but it's essential to use the medication for the entire duration prescribed by your doctor.

Benzalkonium Chloride + Fluorometholone + Tobramycin is not associated with impacting mood. However, different people can react differently to medications. If you notice significant mood changes while using this medicine, consult your doctor.

Benzalkonium Chloride + Fluorometholone + Tobramycin is not associated with affecting hormone levels in the body. However, if you notice any unusual symptoms, you should consult your doctor.

Yes, there is no lactose in this medication, so it can be used by individuals with lactose intolerance.

Some natural remedies can help soothe eye inflammation and irritation but do not have the same antibacterial and anti-inflammatory properties as this medication. Always consult your doctor before trying any alternatives.

This medicine should be used for the duration recommended by your doctor. Prolonged use can lead to potential side effects such as increased risk of secondary eye infections, glaucoma, and cataracts.

Benzalkonium Chloride + Fluorometholone + Tobramycin is not associated with affecting sleep, but if an eye infection or inflammation is causing discomfort and affecting your sleep, relieving these symptoms may indirectly improve your sleep.

Terms & Conditions


Benzalkonium Chloride + Fluorometholone + Tobramycin in other salts

BENZALKONIUM CHLORIDE + CHOLINE SALICYLATE + LIDOCAINE / LIGNOCAINEBENZALKONIUM CHLORIDE + ZINC OXIDEBENZALKONIUM CHLORIDE + BROMFENAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + OFLOXACINBENZALKONIUM CHLORIDE + CYCLOPENTOLATEBENZALKONIUM CHLORIDE + CIPROFLOXACINBENZALKONIUM CHLORIDE + CIPROFLOXACIN + DEXAMETHASONEBENZALKONIUM CHLORIDE + FLUOROMETHOLONEFLUOROMETHOLONEFLUOROMETHOLONE + TOBRAMYCINBENZALKONIUM CHLORIDE + GATIFLOXACINDEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + OFLOXACINBENZALKONIUM CHLORIDE + NEPAFENACTOBRAMYCINBENZALKONIUM CHLORIDE + MOXIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + TOBRAMYCINMOXIFLOXACIN + TOBRAMYCINBENZALKONIUM CHLORIDE + CHOLINE SALICYLATEBENZALKONIUM CHLORIDE + DEXAMETHASONE + TOBRAMYCINBENZALKONIUM CHLORIDE + BRIMONIDINE + TIMOLOLALCAFTADINE + BENZALKONIUM CHLORIDEBENZALKONIUM CHLORIDE + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + FLUCONAZOLEBENZALKONIUM CHLORIDE + KETOROLAC + MOXIFLOXACINBENZALKONIUM CHLORIDE + LATANOPROSTBENZALKONIUM CHLORIDE + OLOPATADINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + BRIMONIDINEBENZALKONIUM CHLORIDE + PHENYLEPHRINE + TROPICAMIDEBENZALKONIUM CHLORIDE + BEPOTASTINEBENZALKONIUM CHLORIDE + BRIMONIDINE + BRINZOLAMIDEBENZALKONIUM CHLORIDE + BIMATOPROSTBENZALKONIUM CHLORIDE + BIMATOPROST + TIMOLOLBENZALKONIUM CHLORIDE + BRINZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + CYCLOSPORINBENZALKONIUM CHLORIDE + KETOROLAC + OLOPATADINEBENZALKONIUM CHLORIDE + DORZOLAMIDEBENZALKONIUM CHLORIDE + DORZOLAMIDE + TIMOLOLBENZALKONIUM CHLORIDE + GATIFLOXACIN + PREDNISOLONEBENZALKONIUM CHLORIDE + LATANOPROST + TIMOLOLBENZALKONIUM CHLORIDE + LOTEPREDNOLBENZALKONIUM CHLORIDE + LOTEPREDNOL + TOBRAMYCINBENZALKONIUM CHLORIDE + DEXAMETHASONE + MOXIFLOXACINBENZALKONIUM CHLORIDE + LOTEPREDNOL + MOXIFLOXACINBENZALKONIUM CHLORIDE + BROMFENACBENZALKONIUM CHLORIDE + MOXIFLOXACINBENZALKONIUM CHLORIDE + OLOPATADINEBENZALKONIUM CHLORIDE + PREDNISOLONEBENZALKONIUM CHLORIDE + TIMOLOL + TRAVOPROSTBENZALKONIUM CHLORIDE + TRAVOPROSTBENZALKONIUM CHLORIDE + NATAMYCINBENZALKONIUM CHLORIDE + CAMPHOR + MENTHOL + NAPHAZOLINE HYDROCHLORIDE + PHENYLEPHRINE HYDROCHLORIDEBENZALKONIUM CHLORIDE + NETARSUDILBENZALKONIUM CHLORIDE + GANCYCLOVIR
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