Berberine

Dosage Forms Available

• Berberine is available for oral administration in the form of capsules, tablets, powders, and liquid extracts.

• For topical application, particularly for canker sores, Berberine is available as a gel.

Age and Dose Restrictions

• Berberine is typically used by adults of age above 18 years. It should not be given to newborns due to the potential risk of worsening jaundice. Children should only take Berberine under strict doctor supervision.

Contraindications

• Individuals with severe liver or kidney disease should avoid taking Berberine.

• This medicine is also contraindicated in patients with bowel obstruction and acute gallbladder or digestive inflammation.

Other Medications to Avoid

• Berberine may interact with diabetes medications (like insulin or metformin), high blood pressure medications (like ACE inhibitors or beta-blockers), antibiotics (such as azithromycin), antifungals (like fluconazole), sedatives (like benzodiazepines), blood thinners (such as warfarin), and immunosuppressant medication such as cyclosporine.

Overdose and Missed Dose

• Overdosing on Berberine can cause symptoms such as lethargy, difficulty breathing, skin flushing or low blood pressure. If you suspect an overdose, seek medical attention immediately.

• If you miss a dose of Berberine, take it as soon as you remember. Do not double up on doses to compensate for a missed dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• Drinking plenty of water may help manage digestive symptoms such as constipation or abdominal pain.

• Resting in a quiet, dimly lit room may help relieve headaches.

• If you experience skin rash, avoid scratching or rubbing the affected area.

Use in Driving and Operating Machinery

• Berberine may cause dizziness or fatigue in some people. If you experience these effects, do not drive or operate heavy machinery until you feel capable.

Use in Pregnancy and Lactation

• Berberine should be avoided during pregnancy and breastfeeding due to potential risks to the baby. Always consult your doctor before taking this medicine if you are pregnant or nursing.

Caution in Other Conditions

• Individuals with low blood pressure should exercise caution when taking Berberine as it may further lower blood pressure.

• If you have a scheduled surgery, discontinue the use of Berberine two weeks before the procedure.

Special Dietary and Lifestyle Recommendations

• Maintain a balanced diet rich in fruits, vegetables, lean proteins and whole grains to support overall health.

• Regular physical activity can help manage conditions like diabetes, high cholesterol and high blood pressure, which are often managed with Berberine.

• Make sure you get adequate sleep each night, as lack of sleep can exacerbate many health conditions.