Biphasic Lispro

Dosage Forms Available

• Biphasic Lispro is available as a suspension for injection, provided in several delivery forms including vials, cartridges, and pre-filled pens.

• This medication is administered through the subcutaneous route, which involves injecting it into the fatty layer just beneath the skin.

Age and Dose Restrictions

• Biphasic Lispro is suitable for use in both adults and children. It can be administered to children who are diagnosed with diabetes and require insulin management.

Contraindications

• This medicine is contraindicated in patients with hypoglycaemia.

• It is also contraindicated for individuals who have shown allergic reactions to insulin lispro or any other components of the formulation.

Other Medications to Avoid

• This medicine may interact with oral diabetes medications (such as metformin and sulfonylureas), beta-blockers (like propranolol and atenolol), corticosteroids (including prednisone and hydrocortisone), and diuretics (such as furosemide and hydrochlorothiazide).

Overdose and Missed Dose

• An overdose of Biphasic Lispro may lead to severe hypoglycemia, characterized by confusion, excessive sweating, trembling, and even loss of consciousness. Immediate medical attention is crucial in such cases.

• If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next scheduled dose. Do not double the next dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage hypoglycemia, carrying a glucose source like candy or glucose tablets can help quickly counteract low blood sugar levels.

• For injection site reactions such as pain or irritation, rotating the site of injection can help alleviate these issues.

Use in Driving and Operating Machinery

• Biphasic Lispro does not directly impair your ability to drive or operate machinery. However, caution should be exercised since hypoglycemia can cause dizziness and blurred vision.

Use in Pregnancy and Lactation

• The use of this medicine during pregnancy or breastfeeding is not recommended without a doctor's advice. It is best to consult your doctor before taking this medication if you are pregnant or nursing..

Caution in Other Conditions

• Caution is advised when administering Biphasic Lispro to patients with liver or kidney disease. These conditions can alter insulin metabolism and effectiveness, necessitating careful monitoring and potentially adjusted dosages.

Special Dietary and Lifestyle Recommendations

• Incorporate a balanced diet that controls carbohydrate intake to help manage blood sugar levels effectively. Consider consulting a nutritionist for a tailored meal plan.

• Regular physical activity can significantly aid in managing diabetes by improving blood glucose control and reducing the need for insulin.

• Maintain regular monitoring of blood glucose levels to help adjust dietary choices and insulin dosages accurately.

• Staying hydrated by drinking adequate amounts of water daily can support overall health and aid in blood sugar regulation.

• Avoid skipping meals to prevent sudden changes in blood glucose levels that could necessitate adjustments in insulin dosage.