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Brimonidine

Uses of Brimonidine

  • Brimonidine is primarily used for managing increased intraocular pressure (IOP) in patients suffering from conditions such as open-angle glaucoma and ocular hypertension. This medication is categorised as an alpha-adrenergic agonist

  • Occasionally, doctors may recommend Brimonidine in conjunction with other medicines to effectively manage these conditions

Side effects of Brimonidine

  • Redness of the eye

  • Itching or burning sensation in the eye

  • Blurred vision

  • Dry eyes

  • Headache

How Brimonidine works

  • Brimonidine is an alpha-2 adrenergic receptor agonist

  • It operates through a dual mechanism. Firstly, it reduces the production of aqueous humour, which is a clear fluid in the eye, by the ciliary body. Secondly, it enhances the outflow of this fluid via the uveoscleral pathway. The combination of these actions helps in decreasing high intraocular pressure (IOP), a condition commonly associated with glaucoma and ocular hypertension

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Brimonidine is available for use via the ocular route (ophthalmic solution)

Age and Dose Restrictions

  • This medication is meant for adults and children above the age of two years

Contraindications

  • Brimonidine is contraindicated in patients with known hypersensitivity to this medicine or any other component of the formulation. Also, it is contraindicated in neonates and infants below 2 years of age

Other Medications to Avoid

  • Brimonidine may interact with monoamine oxidase inhibitors (such as phenelzine, and tranylcypromine), tricyclic antidepressants (such as amitriptyline, and nortriptyline), CNS depressants like sedatives (such as chlordiazepoxide) and tranquillisers (like haloperidol), blood pressure medications like beta-blockers (such as atenolol, metoprolol), antihypertensives (like amlodipine, enalapril), and cardiac glycosides (like digoxin)

Overdose and Missed Dose

  • An overdose of Brimonidine may cause symptoms such as hypotension, hypertension, bradycardia, tachycardia, hypothermia, and hypoxia among others. If you observe these symptoms, promptly consult your doctor

  • If you miss a dose of this medication, administer it as soon as you remember However, if it is almost time for your next dose, skip the missed one and continue with your regular schedule

Management of Side Effects

Most side effects of Brimonidine are temporary, generally harmless, and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor

  • Drinking water can help manage dry mouth

  • Rest and relaxation techniques may assist in relieving headaches and fatigue

Use in Driving and Operating Machinery

  • Brimonidine may cause drowsiness or blurred vision which may affect your ability to drive or operate heavy machinery. Avoid such activities if you experience these effects after using this medicine.

Use in Pregnancy and Lactation

  • It is advised to consult a doctor before using Brimonidine during pregnancy and breastfeeding.

Caution in Other Conditions

  • Caution should be exercised when administering Brimonidine to patients with severe cardiovascular disease, depression, or blood circulation disorders.

  • Elderly patients may also need to take extra caution as they may be more sensitive to the effects of the medicine.

Special Dietary and Lifestyle Recommendations

  • Regular eye check-ups are recommended for individuals diagnosed with ocular hypertension or glaucoma.

  • Protect your eyes from direct sunlight by wearing sunglasses whenever needed.

  • Avoid activities that cause a lot of eye strain, such as excessive reading, watching TV for prolonged periods, or working long hours on a computer.

  • Limit caffeine consumption as it can increase eye pressure.

Frequently asked questions

No, Brimonidine is not a steroid. It belongs to the class of medicines known as alpha-adrenergic agonists, which are used to manage conditions associated with increased eye pressure such as glaucoma and ocular hypertension.

Brimonidine may cause drowsiness as a side effect in some patients. If you feel drowsy after taking Brimonidine, it is important to avoid activities that require alertness such as driving until you feel alert again.

Brimonidine does not affect fertility. However, each individual reacts differently to medications and if you have concerns, you should consult your doctor.

Yes, it is safe to use Brimonidine daily for as long as it is prescribed by your doctor to manage your condition.

The exact time frame varies among individuals, but generally, Brimonidine starts to work within hours after administration.

The best time to administer Brimonidine will be determined by your doctor based on your medical condition and other factors.

The duration of use for Brimonidine depends on your medical condition and response to the medicine. It should only be used as long as prescribed by your doctor.

Terms & Conditions


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